The prion protein and neuronal zinc homeostasis (Q35204580)

7 August 2017

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title

The prion protein and neuronal zinc homeostasis (English)

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7 August 2017

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Nigel M Hooper

2

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author name string

Nicole T Watt

series ordinal

1

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7 August 2017

1 August 2003

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7 August 2017

5

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Trends in Biochemical Sciences

inferred from page(s)

published in

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7 August 2017

28

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7 August 2017

8

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7 August 2017

406-410

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The galvanization of biology: a growing appreciation for the roles of zinc

7 August 2017

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7 January 2021

Carbonic anhydrase gating of attention: memory therapy and enhancement

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7 January 2021

Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Copper stimulates endocytosis of the prion protein

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Zn(2+): a novel ionic mediator of neural injury in brain disease.

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7 January 2021

Movement of zinc and its functional significance in the brain

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Release of endogenous Zn2+ from brain tissue during activity.

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7 January 2021

Mammalian zinc transporters

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7 January 2021

Zinc transport in the brain: routes of zinc influx and efflux in neurons

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7 January 2021

Eukaryotic zinc transporters and their regulation

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7 January 2021

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

1 reference

7 January 2021

Prion and prejudice: normal protein and the synapse

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Copper binding to the prion protein: structural implications of four identical cooperative binding sites

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Location and properties of metal-binding sites on the human prion protein.

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Copper binding to the octarepeats of the prion protein. Affinity, specificity, folding, and cooperativity: insights from circular dichroism

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7 January 2021

B lymphocytes and neuroinvasion

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7 January 2021

Consequences of manganese replacement of copper for prion protein function and proteinase resistance

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Mapping Cu(II) binding sites in prion proteins by diethyl pyrocarbonate modification and matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometric footprinting

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7 January 2021

Short peptides are not reliable models of thermodynamic and kinetic properties of the N-terminal metal binding site in serum albumin

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7 January 2021

Prion Protein Interaction with Glycosaminoglycan Occurs with the Formation of Oligomeric Complexes Stabilized by Cu(II) Bridges

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Internalization of mammalian fluorescent cellular prion protein and N-terminal deletion mutants in living cells

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Mounting evidence for the involvement of zinc and copper in Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Evidence of presynaptic location and function of the prion protein

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Brain copper content and cuproenzyme activity do not vary with prion protein expression level

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Molecular features of the copper binding sites in the octarepeat domain of the prion protein

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

More than just a membrane anchor

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Signal transduction through prion protein

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Cellular prion protein transduces neuroprotective signals

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7 January 2021

Functions of zinc in signaling, proliferation and differentiation of mammalian cells

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7 January 2021

Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities

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7 January 2021

Metal imbalance and compromised antioxidant function are early changes in prion disease

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7 January 2021

Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126.

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7 January 2021

TSE agent strains and PrP: reconciling structure and function.

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Strain-specific prion-protein conformation determined by metal ions

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https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

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7 January 2021

Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

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7 January 2021

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

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7 January 2021

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

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7 January 2021

Treatment of Alzheimer's disease with clioquinol

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7 January 2021

Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the protein

1 reference

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7 January 2021

Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2803%2900166-X

7 January 2021

10.1016/S0968-0004(03)00166-X

Identifiers

DOI

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7 August 2017

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PubMed ID

12932728