Comparative pharmacokinetic properties and antitumor activity of the marine HDACi Largazole and Largazole peptide isostere (Q35202369)

7 August 2017

Comparative pharmacokinetic properties and antitumor activity of the marine HDACi Largazole and Largazole peptide isostere (English)

1 reference

7 August 2017

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7

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1 June 2020

author name string

John L Pilon

1

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1 June 2020

Dane J Clausen

2

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1 June 2020

Ryan J Hansen

3

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1 June 2020

Paul J Lunghofer

4

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1 June 2020

Brad Charles

5

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1 June 2020

Barbara J Rose

6

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Daniel L Gustafson

8

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1 June 2020

James E Bradner

9

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1 June 2020

Robert M Williams

10

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1 June 2020

language of work or name

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24 January 2015

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Cancer Chemotherapy and Pharmacology

7 August 2017

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1 June 2020

volume

75

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1 June 2020

page(s)

671-682

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1 June 2020

issue

4

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https://scigraph.springernature.com/pub.10.1007/s00280-015-2675-1

1 June 2020

exact match

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cites work

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Structural Basis of the Antiproliferative Activity of Largazole, a Depsipeptide Inhibitor of the Histone Deacetylases

28 July 2018

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Total synthesis of largazole and analogues: HDAC inhibition, antiproliferative activity and metabolic stability.

28 July 2018

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Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.

28 July 2018

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Chemical phylogenetics of histone deacetylases

28 July 2018

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The HDAC inhibitor panobinostat (LBH589) inhibits mesothelioma and lung cancer cells in vitro and in vivo with particular efficacy for small cell lung cancer

28 July 2018

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Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold

28 July 2018

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Population pharmacokinetics of romidepsin in patients with cutaneous T-cell lymphoma and relapsed peripheral T-cell lymphoma

28 July 2018

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Synthesis and conformation-activity relationships of the peptide isosteres of FK228 and largazole

28 July 2018

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Total synthesis and biological mode of action of largazole: a potent class I histone deacetylase inhibitor

28 July 2018

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Structure and activity of largazole, a potent antiproliferative agent from the Floridian marine cyanobacterium Symploca sp.

28 July 2018

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Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

28 July 2018

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Discovery and development of SAHA as an anticancer agent

28 July 2018

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Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1.

28 July 2018

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Improving the decision-making process in the structural modification of drug candidates: enhancing metabolic stability

28 July 2018

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PANORAMA 2: panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma

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Total synthesis and molecular target of largazole, a histone deacetylase inhibitor

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MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo

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Crossref

https://api.crossref.org/works/10.1007%2FS00280-015-2675-1

10.1007/S00280-015-2675-1

21 January 2018

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1 June 2020

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