SLC13A5 is a novel transcriptional target of the pregnane X receptor and sensitizes drug-induced steatosis in human liver (Q35198043)

7 August 2017

title

SLC13A5 is a novel transcriptional target of the pregnane X receptor and sensitizes drug-induced steatosis in human liver (English)

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7 August 2017

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Linhao Li

1

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7 August 2017

Haishan Li

2

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7 August 2017

Brandy Garzel

3

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7 August 2017

Hui Yang

4

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7 August 2017

Tatsuya Sueyoshi

5

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7 August 2017

Qing Li

6

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7 August 2017

Yan Shu

7

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7 August 2017

Junran Zhang

8

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7 August 2017

Bingfang Hu

9

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7 August 2017

Scott Heyward

10

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7 August 2017

Timothy Moeller

11

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7 August 2017

Wen Xie

12

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7 August 2017

Masahiko Negishi

13

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7 August 2017

Hongbing Wang

14

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7 August 2017

publication date

27 January 2015

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7 August 2017

published in

Molecular Pharmacology

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7 August 2017

volume

87

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7 August 2017

issue

4

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7 August 2017

page(s)

674-682

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describes a project that uses

7 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4366797/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Regulation of cell morphology and cytochrome P450 expression in human hepatocytes by extracellular matrix and cell-cell interactions

28 July 2018

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Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

28 July 2018

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28 July 2018

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28 July 2018

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The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module

28 July 2018

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The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile.

26 September 2018

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Elucidating the 'Jekyll and Hyde' nature of PXR: the case for discovering antagonists or allosteric antagonists

26 September 2018

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The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor.

26 September 2018

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Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole.

26 September 2018

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A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366797

Sequence and functional characterization of a renal sodium/dicarboxylate cotransporter

26 September 2018

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26 September 2018

Identifiers

DOI

10.1124/MOL.114.097287

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7 August 2017

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7 August 2017

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