Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL. (Q35190609)

7 August 2017

Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL. (English)

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7 August 2017

M L Sulis

1

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7 August 2017

P Saftig

series ordinal

2

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7 August 2017

A A Ferrando

series ordinal

3

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7 August 2017

language of work or name

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31 May 2011

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7 August 2017

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7 August 2017

25

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7 August 2017

10

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7 August 2017

1564-1569

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https://scigraph.springernature.com/pub.10.1038/leu.2011.130

7 August 2017

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cites work

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Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia

13 July 2018

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Therapeutic antibody targeting of individual Notch receptors

13 July 2018

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Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors

13 July 2018

1 reference

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The role of NOTCH1 signaling in T-ALL.

13 July 2018

1 reference

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Metalloprotease ADAM10 is required for Notch1 site 2 cleavage.

13 July 2018

1 reference

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Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling

13 July 2018

1 reference

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Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

13 July 2018

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The ADAMs: signalling scissors in the tumour microenvironment

13 July 2018

1 reference

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Oncogenic NOTCH1 control of MYC and PI3K: challenges and opportunities for anti-NOTCH1 therapy in T-cell acute lymphoblastic leukemias and lymphomas

13 July 2018

1 reference

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NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL.

13 July 2018

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Notch signaling in leukemia

13 July 2018

1 reference

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The EGF receptor family: spearheading a merger of signaling and therapeutics

13 July 2018

1 reference

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Targeting TACE-dependent EGFR ligand shedding in breast cancer

13 July 2018

1 reference

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Notch signalling: a simple pathway becomes complex

13 July 2018

1 reference

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Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer

13 July 2018

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Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes

13 July 2018

1 reference

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CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to gamma-secretase inhibitors

13 July 2018

1 reference

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A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3165074

ADAMs: key components in EGFR signalling and development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3165074

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

13 July 2018

1 reference

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The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3165074

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3165074

The metalloprotease-disintegrin Kuzbanian participates in Notch activation during growth and patterning of Drosophila imaginal discs

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3165074

Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3165074

ADAM10 is essential for proteolytic activation of Notch during thymocyte development.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3165074

Impairment of thymocyte development by dominant-negative Kuzbanian (ADAM-10) is rescued by the Notch ligand, delta-1.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3165074

SUP-17, a Caenorhabditis elegans ADAM protein related to Drosophila KUZBANIAN, and its role in LIN-12/NOTCH signalling.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3165074

Acute lymphoblastic leukaemia

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FLEU.2011.130

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21625236

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/LEU.2011.130

1 reference

Dimensions Publication ID

7 August 2017

0 references

1 reference

7 August 2017

1 reference