Quantifying ligand bias at seven-transmembrane receptors. (Q35188090)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21610196%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Quantifying ligand bias at seven-transmembrane receptors (English)

1 reference

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2 February 2020

main subject

transmembrane protein

0 references

1 reference

1

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2 February 2020

Scott M DeWire

6

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2 February 2020

8

Robert J Lefkowitz

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2 February 2020

author name string

Seungkirl Ahn

2

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2 February 2020

David H Rominger

3

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2 February 2020

William Gowen-MacDonald

4

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2 February 2020

Christopher M Lam

5

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2 February 2020

Jonathan D Violin

7

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2 February 2020

publication date

24 May 2011

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2 February 2020

published in

Molecular Pharmacology

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2 February 2020

volume

80

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2 February 2020

issue

3

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2 February 2020

page(s)

367-377

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Therapeutic potential of β-arrestin- and G protein-biased agonists.

2 February 2020

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Selectively engaging β-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance.

13 July 2018

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Teaching old receptors new tricks: biasing seven-transmembrane receptors

13 July 2018

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A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation.

13 July 2018

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Morphine-like opiates selectively antagonize receptor-arrestin interactions.

13 July 2018

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Identification of orthosteric and allosteric site mutations in M2 muscarinic acetylcholine receptors that contribute to ligand-selective signaling bias

13 July 2018

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On the analysis of ligand-directed signaling at G protein-coupled receptors

13 July 2018

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The genetic design of signaling cascades to record receptor activation

13 July 2018

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beta-arrestin-biased agonism at the beta2-adrenergic receptor

13 July 2018

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A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling

13 July 2018

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Functional selectivity through protean and biased agonism: who steers the ship?

13 July 2018

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Emerging concepts of guanine nucleotide-binding protein-coupled receptor (GPCR) function and implications for high throughput screening

13 July 2018

1 reference

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Beta-arrestins and cell signaling

13 July 2018

1 reference

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Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes

13 July 2018

1 reference

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Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy

13 July 2018

1 reference

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Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.

13 July 2018

1 reference

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A modification of receptor theory

13 July 2018

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Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

13 July 2018

1 reference

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Mutations inducing divergent shifts of constitutive activity reveal different modes of binding among catecholamine analogues to the beta(2)-adrenergic receptor

13 July 2018

1 reference

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Efficacy in drug receptor theory: outdated concept or under-valued tool?

13 July 2018

1 reference

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Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus.

13 July 2018

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Agonist-receptor efficacy. II. Agonist trafficking of receptor signals

13 July 2018

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A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor

13 July 2018

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Operational models of pharmacological agonism.

13 July 2018

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Interaction of beta-adrenergic receptors with the inhibitory guanine nucleotide-binding protein of adenylate cyclase in membranes prepared from cyc- S49 lymphoma cells

13 July 2018

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Effector coupling mechanisms of the cloned 5-HT1A receptor

13 July 2018

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Quantification of functional selectivity at the human α(1A)-adrenoceptor.

13 July 2018

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Selectivity of agonists for the active state of M1 to M4 muscarinic receptor subtypes

27 September 2018

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27 September 2018

1 reference

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Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors.

27 September 2018

1 reference

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Imprecision in presentation of binding studies

27 September 2018

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1124/MOL.111.072801

Identifiers

DOI

10.1124/MOL.111.072801

1 reference

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2 February 2020

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2 February 2020

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