Increased protection against pneumococcal disease by mucosal administration of conjugate vaccine plus interleukin-12. (Q35165637)

6 August 2017

Increased protection against pneumococcal disease by mucosal administration of conjugate vaccine plus interleukin-12. (English)

1 reference

6 August 2017

0 references

2

David E Briles

1 reference

6 August 2017

Joyce M Lynch

1

1 reference

PubMed ID

12874361

6 August 2017

Dennis W Metzger

series ordinal

3

1 reference

PubMed ID

12874361

6 August 2017

language of work or name

English

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publication date

1 August 2003

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6 August 2017

Infection and Immunity

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6 August 2017

71

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6 August 2017

8

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6 August 2017

4780-4788

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Intranasal immunization with pneumococcal conjugate vaccines with LT-K63, a nontoxic mutant of heat-Labile enterotoxin, as adjuvant rapidly induces protective immunity against lethal pneumococcal infections in neonatal mice

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Intranasal vaccination with pneumococcal surface protein A and interleukin-12 augments antibody-mediated opsonization and protective immunity against Streptococcus pneumoniae infection.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Comparative in vivo analysis of IgA- and IgG-mediated mucosal defense against bacterial pathogens.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Induction of mucosal immune responses against a heterologous antigen fused to filamentous hemagglutinin after intranasal immunization with recombinant Bordetella pertussis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Streptococcus pneumoniae: virulence factors, pathogenesis, and vaccines.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Phase variation in pneumococcal opacity: relationship between colonial morphology and nasopharyngeal colonization

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Anti-polysaccharide immunoglobulin isotype levels and opsonic activity of antisera: relationships with protection against Streptococcus pneumoniae infection in mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Structure and function of human and murine receptors for IgG.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

H chain C domains influence the strength of binding of IgG for streptococcal group A carbohydrate.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Delivery of IL-12 intranasally leads to reduced IL-12-mediated toxicity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Negligible adjuvant effect for antibody responses and frequent adverse events associated with IL-12 treatment in humans vaccinated with pneumococcal polysaccharide

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

IgA immunodeficiency leads to inadequate Th cell priming and increased susceptibility to influenza virus infection

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Serum antibody and opsonic responses to vaccination with pneumococcal capsular polysaccharide in normal and splenectomized children.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166054

Neonatal administration of IL-12 enhances the protective efficacy of antiviral vaccines

27 September 2018

1 reference

12 December 2020

Reduction of nasopharyngeal carriage of pneumococci during the second year of life by a heptavalent conjugate pneumococcal vaccine

1 reference

12 December 2020

IL-12-mediated increases in protection elicited by pneumococcal and meningococcal conjugate vaccines

1 reference

12 December 2020

Isotypes of mouse IgG--I. Evidence for 'non-complement-fixing' IgG1 antibodies and characterization of their capacity to interfere with IgG2 sensitization of target red blood cells for lysis by complement

1 reference

12 December 2020

Natural and vaccine-related immunity to Streptococcus pneumoniae

1 reference

12 December 2020

Opsonization and antibodies to capsular and cell wall polysaccharides of Streptococcus pneumoniae

1 reference

12 December 2020

Interleukin-12 profoundly up-regulates the synthesis of antigen-specific complement-fixing IgG2a, IgG2b and IgG3 antibody subclasses in vivo

1 reference

12 December 2020

Pathogenesis of Pneumococcal Infection

1 reference

12 December 2020

Intranasal immunization of mice with PspA (pneumococcal surface protein A) can prevent intranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae

1 reference

12 December 2020

Interleukin-12 acts as an adjuvant for humoral immunity through interferon-gamma-dependent and -independent mechanisms

1 reference

12 December 2020

Association of intrastrain phase variation in quantity of capsular polysaccharide and teichoic acid with the virulence of Streptococcus pneumoniae

1 reference

12 December 2020

IL-12 enhances antibody responses to T-independent polysaccharide vaccines in the absence of T and NK cells

1 reference

12 December 2020

Targeted deletion of the IgA constant region in mice leads to IgA deficiency with alterations in expression of other Ig isotypes

1 reference

12 December 2020

Intranasal interleukin-12 is a powerful adjuvant for protective mucosal immunity

1 reference

12 December 2020

Carriage of pneumococci after pneumococcal vaccination

1 reference

12 December 2020

IL-12 enhances vaccine-induced immunity to schistosomes by augmenting both humoral and cell-mediated immune responses against the parasite

1 reference

12 December 2020

10.1128/IAI.71.8.4780-4788.2003

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference

PubMed ID

12874361