Metal ion binding to catalytic RNA molecules (Q35165227)

6 August 2017

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title

Metal ion binding to catalytic RNA molecules (English)

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6 August 2017

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Victoria J DeRose

1

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6 August 2017

publication date

1 June 2003

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Current Opinion in Structural Biology

6 August 2017

published in

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6 August 2017

volume

13

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6 August 2017

issue

3

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6 August 2017

page(s)

317-324

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The chemical repertoire of natural ribozymes

6 August 2017

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Two decades of RNA catalysis

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Metal ions in the structure and function of RNA.

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The linkage between magnesium binding and RNA folding.

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Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations.

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7 January 2021

Mechanistic characterization of the HDV genomic ribozyme: assessing the catalytic and structural contributions of divalent metal ions within a multichannel reaction mechanism

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7 January 2021

Metal ion binding sites in a group II intron core

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7 January 2021

The rate-limiting step in the folding of a large ribozyme without kinetic traps

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7 January 2021

Folding and activity of the hammerhead ribozyme

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7 January 2021

Assembly of core helices and rapid tertiary folding of a small bacterial group I ribozyme

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Solvent Protection of the Hammerhead Ribozyme in the Ground State: Evidence for a Cation-Assisted Conformational Change Leading to Catalysis

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7 January 2021

Rapid compaction during RNA folding

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7 January 2021

Single-molecule folding

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7 January 2021

Mechanistic characterization of the HDV genomic ribozyme: classifying the catalytic and structural metal ion sites within a multichannel reaction mechanism.

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Developments in RNA chemistry, a personal view

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7 January 2021

Phosphorothioate substitution can substantially alter RNA conformation

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7 January 2021

Metal interactions with a GAAA RNA tetraloop characterized by (31)P NMR and phosphorothioate substitutions

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7 January 2021

Impact of phosphorothioate substitutions on the thermodynamic stability of an RNA GAAA tetraloop: an unexpected stabilization

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7 January 2021

Metal-phosphate interactions in the hammerhead ribozyme observed by 31P NMR and phosphorothioate substitutions

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7 January 2021

A pH-dependent conformational change, rather than the chemical step, appears to be rate-limiting in the hammerhead ribozyme cleavage reaction

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7 January 2021

Identification of the hammerhead ribozyme metal ion binding site responsible for rescue of the deleterious effect of a cleavage site phosphorothioate

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7 January 2021

A reappraisal, based on (31)P NMR, of the direct coordination of a metal ion with the phosphoryl oxygen at the cleavage site of a hammerhead ribozyme

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7 January 2021

Identification of the metal ion binding site on an RNA motif from hammerhead ribozymes using (15)N NMR spectroscopy

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7 January 2021

Metal binding and base ionization in the U6 RNA intramolecular stem-loop structure

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7 January 2021

Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.

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7 January 2021

Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reaction

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7 January 2021

Evidence for a polynuclear metal ion binding site in the catalytic domain of ribonuclease P RNA.

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7 January 2021

Kinetic characterization of the second step of group II intron splicing: role of metal ions and the cleavage site 2'-OH in catalysis

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7 January 2021

Structural analysis of metal ion ligation to nucleotides and nucleic acids using pulsed EPR spectroscopy

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7 January 2021

Mechanistic considerations for general acid-base catalysis by RNA: revisiting the mechanism of the hairpin ribozyme

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7 January 2021

10.1016/S0959-440X(03)00077-0

Identifiers

DOI

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6 August 2017

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