Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells (Q35165105)

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English	Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells (English)

1 reference

Europe PubMed Central

6 August 2017

1 reference

based on heuristic

inferred from title

3

1 reference

Europe PubMed Central

6 August 2017

Boris Kholodenko

4

1 reference

Europe PubMed Central

6 August 2017

Edita Aksamitiene

object named as

Edita Aksamitiene

1

0 references

Anatoly Kiyatkin

object named as

Anatoly Kiyatkin

6

0 references

object named as

Jan B Hoek

5

0 references

author name string

Sirisha Achanta

2

1 reference

Europe PubMed Central

6 August 2017

publication date

25 June 2011

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Europe PubMed Central

6 August 2017

number of pages

12

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based on heuristic

inferred from page(s)

Cellular Signalling

1 reference

Europe PubMed Central

6 August 2017

23

1 reference

Europe PubMed Central

6 August 2017

1794-1805

1 reference

Europe PubMed Central

6 August 2017

11

1 reference

Europe PubMed Central

6 August 2017

PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156300

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An allosteric kinase inhibitor binds the p21-activated kinase autoregulatory domain covalently.

1 reference

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New mechanisms for PRLr action in breast cancer

1 reference

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Pak protein kinases and their role in cancer

1 reference

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28 July 2018

SRC family kinases accelerate prolactin receptor internalization, modulating trafficking and signaling in breast cancer cells

1 reference

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Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3.

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The RSK family of kinases: emerging roles in cellular signalling

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Physiological roles of ribosomal protein S6: one of its kind

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p21 activated kinase 5 activates Raf-1 and targets it to mitochondria

1 reference

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Regulation of prolactin receptor levels and activity in breast cancer

1 reference

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The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway

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1 reference

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2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase

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Cellular characterization of a novel focal adhesion kinase inhibitor

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Essential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4.

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Pak4 induces premature senescence via a pathway requiring p16INK4/p19ARF and mitogen-activated protein kinase signaling

1 reference

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Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors

1 reference

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Prolonged extracellular signal-regulated kinase 1/2 activation during fibroblast growth factor 1- or heregulin beta1-induced antiestrogen-resistant growth of breast cancer cells is resistant to mitogen-activated protein/extracellular regulated kinas

1 reference

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p21-activated Kinase-1 Signaling Mediates Cyclin D1 Expression in Mammary Epithelial and Cancer Cells

1 reference

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Chemical Dissection of the Effects of Tyrosine Phosphorylation of SHP-2

1 reference

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Biology of the p21-activated kinases

1 reference

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28 July 2018

The role of prolactin in mammary carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156300

28 July 2018

p21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling

1 reference

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Interfering with Ras signaling using membrane-permeable peptides or drugs

1 reference

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28 July 2018

Prolactin induces SHP-2 association with Stat5, nuclear translocation, and binding to the beta-casein gene promoter in mammary cells

1 reference

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Characterization of an activated mutant of focal adhesion kinase: 'SuperFAK'

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Ten years of protein kinase B signalling: a hard Akt to follow

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28 July 2018

Site-specific incorporation of a phosphotyrosine mimetic reveals a role for tyrosine phosphorylation of SHP-2 in cell signaling

1 reference

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SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling

1 reference

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28 July 2018

Cellular signaling: pivoting around PDK-1.

1 reference

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28 July 2018

p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).

1 reference

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Mammary gland development and the prolactin receptor

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IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled

1 reference

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Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway

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28 July 2018

Constitutive activation of the prolactin receptor results in the induction of growth factor-independent proliferation and constitutive activation of signaling molecules

1 reference

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The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus

1 reference

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28 July 2018

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156300

28 July 2018

Prolactin activates Stat1 but does not antagonize Stat1 activation and growth inhibition by type I interferons in human breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156300

28 July 2018

Cellular functions regulated by Src family kinases

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Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156300

28 July 2018

Focal adhesion kinase tyrosine-861 is a major site of phosphorylation by Src.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3156300

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Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

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Involvement of SHC, GRB2, SOS and RAS in prolactin signal transduction in mammary epithelial cells.

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The GRB2/Sem-5 adaptor protein

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Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK.

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Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

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Prolactin receptors in human breast cancer cells in long-term tissue culture

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New concepts in prolactin biology

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27 September 2018

Novel roles of prolactin and estrogens in breast cancer: resistance to chemotherapy

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A prospective study of plasma prolactin concentrations and risk of premenopausal and postmenopausal breast cancer.

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Loss of mammary epithelial prolactin receptor delays tumor formation by reducing cell proliferation in low-grade preinvasive lesions.

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27 September 2018

Expression of prolactin receptors in normal, benign, and malignant breast tissue: an immunohistological study

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27 September 2018

Quantification of prolactin receptor mRNA in multiple human tissues and cancer cell lines by real time RT-PCR.

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27 September 2018

PTP1D is a positive regulator of the prolactin signal leading to beta-casein promoter activation.

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27 September 2018

Prolactin activates Ras via signaling proteins SHC, growth factor receptor bound 2, and son of sevenless.

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Multistrip western blotting to increase quantitative data output

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolactin as a Chemoattractant for Human Breast Carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21726627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Src family kinases are required for prolactin induction of cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21726627

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CELLSIG.2011.06.014

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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