Anthrax lethal factor as an immune target in humans and transgenic mice and the impact of HLA polymorphism on CD4+ T cell immunity (Q35161514)

6 August 2017

title

Anthrax lethal factor as an immune target in humans and transgenic mice and the impact of HLA polymorphism on CD4+ T cell immunity (English)

1 reference

6 August 2017

Stephanie Ascough

1

0 references

Les Baillie

Les Baillie

9

0 references

Daniel Altmann

Daniel M Altmann

18

0 references

Rebecca J Ingram

Rebecca J Ingram

2

0 references

Shiranee Sriskandan

Shiranee Sriskandan

10

0 references

author name string

Karen K Chu

3

1 reference

6 August 2017

Catherine J Reynolds

4

1 reference

6 August 2017

Julie A Musson

5

1 reference

6 August 2017

Mehmet Doganay

6

1 reference

6 August 2017

Gökhan Metan

7

1 reference

6 August 2017

Yusuf Ozkul

8

1 reference

6 August 2017

Stephen J Moore

11

1 reference

6 August 2017

Theresa B Gallagher

12

1 reference

6 August 2017

Hugh Dyson

13

1 reference

6 August 2017

E Diane Williamson

14

1 reference

6 August 2017

John H Robinson

15

1 reference

6 August 2017

Bernard Maillere

16

1 reference

6 August 2017

Rosemary J Boyton

17

1 reference

6 August 2017

publication date

1 May 2014

1 reference

6 August 2017

1 reference

6 August 2017

volume

10

1 reference

6 August 2017

issue

5

1 reference

6 August 2017

page(s)

e1004085

1 reference

Creative Commons Attribution 4.0 International

6 August 2017

copyright license

start time

1 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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HLA and infectious diseases

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Past, imminent and future human medical countermeasures for anthrax

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Protection against anthrax lethal toxin challenge by genetic immunization with a plasmid encoding the lethal factor protein

13 July 2018

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Structural basis for HLA-DQ binding by the streptococcal superantigen SSA

13 July 2018

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Effect of T-helper cytokine environment on specificity of T-cell responses to mycobacterial 65,000 MW heat-shock protein

13 July 2018

1 reference

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Lethal factor active-site mutations affect catalytic activity in vitro.

13 July 2018

1 reference

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Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

13 July 2018

1 reference

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Binding of malaria T cell epitopes to DR and DQ molecules in vitro correlates with immunogenicity in vivo: identification of a universal T cell epitope in the Plasmodium falciparum circumsporozoite protein

13 July 2018

1 reference

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HLA-DR4-IE chimeric class II transgenic, murine class II-deficient mice are susceptible to experimental allergic encephalomyelitis

13 July 2018

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Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides

13 July 2018

1 reference

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Residues 1-254 of anthrax toxin lethal factor are sufficient to cause cellular uptake of fused polypeptides

13 July 2018

1 reference

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Characterization of macrophage sensitivity and resistance to anthrax lethal toxin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006929

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.

13 July 2018

1 reference

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Mouse mammary tumor virus-mediated T-cell receptor negative selection in HLA-DRA transgenic mice

13 July 2018

1 reference

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Protective immunity induced by Bacillus anthracis toxin-deficient strains.

13 July 2018

1 reference

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Purification and properties of in vitro-produced anthrax toxin components

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006929

Antibodies to anthrax toxin in humans and guinea pigs and their relevance to protective immunity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006929

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006929

Relative contribution of "determinant selection" and "holes in the T-cell repertoire" to T-cell responses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006929

The relation between major histocompatibility complex (MHC) restriction and the capacity of Ia to bind immunogenic peptides

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006929

Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006929

Anthrax vaccines: past, present and future

13 July 2018

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B. anthracis in a wool-processing factory: seroprevalence and occupational risk

13 July 2018

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Natural exposure to cutaneous anthrax gives long-lasting T cell immunity encompassing infection-specific epitopes

27 September 2018

1 reference

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An outbreak of infection with Bacillus anthracis in injecting drug users in Scotland.

27 September 2018

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Immunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: implications for vaccine design

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006929

Tetramer-guided epitope mapping reveals broad, individualized repertoires of tetanus toxin-specific CD4+ T cells and suggests HLA-based differences in epitope recognition

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006929

Anthrax lethal toxin has direct and potent inhibitory effects on B cell proliferation and immunoglobulin production.

27 September 2018

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Patterns of antibody response in humans to the anthrax vaccine adsorbed (AVA) primary (six-dose) series.

27 September 2018

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Anthrax lethal toxin blocks MAPK kinase-dependent IL-2 production in CD4+ T cells

27 September 2018

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Anthrax capsule vaccine protects against experimental infection

27 September 2018

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Production and purification of Bacillus anthracis protective antigen from Escherichia coli

27 September 2018

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Characterization of the human immune response to the UK anthrax vaccine

27 September 2018

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27 September 2018

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Genetic immunization against anthrax

27 September 2018

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Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin

27 September 2018

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Novel promiscuous HLA-DQ HIV Nef peptide that induces IFN-gamma-producing memory CD4+ T cells.

27 September 2018

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HLA-DQ tetramers identify epitope-specific T cells in peripheral blood of herpes simplex virus type 2-infected individuals: direct detection of immunodominant antigen-responsive cells

27 September 2018

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Human immune responses to the UK human anthrax vaccine

27 September 2018

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A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006929

High Incidence of Spontaneous Disease in an HLA-DR15 and TCR Transgenic Multiple Sclerosis Model

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004085

Glutamic acid decarboxylase T lymphocyte responses associated with susceptibility or resistance to type I diabetes: analysis in disease discordant human twins, non-obese diabetic mice and HLA-DQ transgenic mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004085

HLA-DQB1*0602 Determines Disease Susceptibility in a New "Humanized" Multiple Sclerosis Model in HLA-DR15 (DRB1*1501;DQB1*0602) Transgenic Mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004085

The adenylate cyclase toxin of Bacillus anthracis is a potent promoter of TH17 cell development

21 January 2018

1 reference

12 December 2020

Antigenic peptide binding by class I and class II histocompatibility proteins

1 reference

12 December 2020

HLA-DR restricted peptide candidates for bee venom immunotherapy

1 reference

12 December 2020

Adverse medical events in British service personnel following anthrax vaccination

1 reference

12 December 2020

The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance

1 reference

12 December 2020

Anthrax lethal toxin-induced mitogenic response of human T-cells

1 reference

12 December 2020

Immunogenicity and tolerance of ascending doses of a recombinant protective antigen (rPA102) anthrax vaccine: a randomized, double-blinded, controlled, multicenter trial

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1004085

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference