Macrophage cholesterol transport: a critical player in foam cell formation (Q35160967)

6 August 2017

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title

Macrophage cholesterol transport: a critical player in foam cell formation (English)

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6 August 2017

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Saara Vainio

1

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PubMed ID

12822736

6 August 2017

Elina Ikonen

series ordinal

2

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PubMed ID

12822736

6 August 2017

language of work or name

English

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publication date

1 January 2003

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6 August 2017

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6 August 2017

35

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6 August 2017

146-155

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6 August 2017

3

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Atherosclerosis. the road ahead

6 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Macrophage foam cells and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Consequences of cellular cholesterol accumulation: basic concepts and physiological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Regulation and mechanisms of macrophage cholesterol efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Arterial retention of apolipoprotein B(48)- and B(100)-containing lipoproteins in atherogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Mechanisms for oxidizing low-density lipoprotein. Insights from patterns of oxidation products in the artery wall and from mouse models of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

T and B lymphocytes play a minor role in atherosclerotic plaque formation in the apolipoprotein E-deficient mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Macrophage scavenger receptor class A: A multifunctional receptor in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

The multiple roles of macrophage scavenger receptors (MSR) in vivo: resistance to atherosclerosis and susceptibility to infection in MSR knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Loss of SR-BI expression leads to the early onset of occlusive atherosclerotic coronary artery disease, spontaneous myocardial infarctions, severe cardiac dysfunction, and premature death in apolipoprotein E-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Cholesterol and phospholipid metabolism in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Intracellular cholesterol trafficking: role of the NPC1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Identification of HE1 as the second gene of Niemann-Pick C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Vesicular and non-vesicular sterol transport in living cells. The endocytic recycling compartment is a major sterol storage organelle

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Modulation of cellular cholesterol transport and homeostasis by Rab11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Caveolin, cholesterol, and lipid droplets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Acyl-coenzyme A:cholesterol acyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Activation of acyl-coenzyme A:cholesterol acyltransferase by cholesterol or by oxysterol in a cell-free system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Free cholesterol loading of macrophages induces apoptosis involving the fas pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Free cholesterol loading of macrophages is associated with widespread mitochondrial dysfunction and activation of the mitochondrial apoptosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Macrophages deficient in CTP:Phosphocholine cytidylyltransferase-alpha are viable under normal culture conditions but are highly susceptible to free cholesterol-induced death. Molecular genetic evidence that the induction of phosphatidylcholine bios

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Mass spectrometric analysis reveals an increase in plasma membrane polyunsaturated phospholipid species upon cellular cholesterol loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Do oxysterols control cholesterol homeostasis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Release of cellular cholesterol: molecular mechanism for cholesterol homeostasis in cells and in the body

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Regulation of peroxisome proliferator-activated receptor-gamma-mediated gene expression. A new mechanism of action for high density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

ABCA1: regulation, trafficking and association with heteromeric proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

ATP-binding cassette transporter A1 and cholesterol trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Evidence that phospholipids play a key role in pre-beta apoA-I formation and high-density lipoprotein remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Increased atherosclerosis in hyperlipidemic mice with inactivation of ABCA1 in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Nuclear receptors and lipid physiology: opening the X-files

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Peroxisome proliferator-activated receptor agonists, hyperlipidaemia, and atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Mechanism of action of fibrates on lipid and lipoprotein metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Peroxisome proliferator-activated receptor-alpha activation and high-density lipoprotein metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Role of LXRs in control of lipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

The hypocholesterolemic agent LY295427 up-regulates INSIG-1, identifying the INSIG-1 protein as a mediator of cholesterol homeostasis through SREBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890310008198

10.1080/07853890310008198

21 January 2018

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12822736