Drug-selected coexpression of human glucocerebrosidase and P-glycoprotein using a bicistronic vector (Q35159720)

6 August 2017

title

Drug-selected coexpression of human glucocerebrosidase and P-glycoprotein using a bicistronic vector (English)

1 reference

6 August 2017

Aran JM

1

1 reference

6 August 2017

Gottesman MM

series ordinal

2

1 reference

6 August 2017

Pastan I

series ordinal

3

1 reference

6 August 2017

language of work or name

English

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publication date

1 April 1994

1 reference

Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

91

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6 August 2017

issue

8

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6 August 2017

page(s)

3176-3180

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Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes.

6 August 2017

cites work

1 reference

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Dicistronic transcription units for gene expression in mammalian cells

28 July 2018

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Biochemistry of multidrug resistance mediated by the multidrug transporter

28 July 2018

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Retrovirus-mediated gene transfer to cystic fibrosis airway epithelial cells: effect of selectable marker sequences on long-term expression

28 July 2018

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Mutations of glucocerebrosidase: discrimination of neurologic and non-neurologic phenotypes of Gaucher disease

28 July 2018

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Processing and lysosomal localization of a glycoprotein whose secretion is transformation stimulated

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43538

Biosynthesis of the lysosomal enzyme glucocerebrosidase

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43538

The molecular biology of Gaucher disease and the potential for gene therapy

28 July 2018

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A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells

28 July 2018

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A new vector using the human multidrug resistance gene as a selectable marker enables overexpression of foreign genes in eukaryotic cells

28 July 2018

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Expression of a human multidrug resistance cDNA (MDR1) in the bone marrow of transgenic mice: resistance to daunomycin-induced leukopenia

28 July 2018

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Expression of a multidrug resistance-adenosine deaminase fusion gene.

28 July 2018

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Use of a cloned multidrug resistance gene for coamplification and overproduction of major excreted protein, a transformation-regulated secreted acid protease

28 July 2018

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Expression of a multidrug-resistance gene in human tumors and tissues

28 July 2018

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Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies

28 July 2018

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Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells

28 July 2018

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Expression of the human multidrug transporter in insect cells by a recombinant baculovirus

28 July 2018

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Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance

28 July 2018

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Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus

28 July 2018

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High levels of human glucocerebrosidase activity in macrophages of long-term reconstituted mice after retroviral infection of hematopoietic stem cells

28 July 2018

1 reference

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Gaucher disease: new molecular approaches to diagnosis and treatment

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43538

Long-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cells

28 July 2018

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Efficient transfer and sustained high expression of the human glucocerebrosidase gene in mice and their functional macrophages following transplantation of bone marrow transduced by a retroviral vector

28 July 2018

1 reference

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Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured Gaucher bone marrow

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43538

Transfer and expression of the human multiple drug resistance gene into live mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43538

Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43538

Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43538

Two species of lysosomal organelles in cultured human fibroblasts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43538

Purification and characterization of a transformation-dependent protein secreted by cultured murine fibroblasts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43538

Detection of the defect of Gaucher's disease and its carrier state in peripheral-blood leucocytes

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7909160

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7909160

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Replacement therapy for inherited enzyme deficiency--macrophage-targeted glucocerebrosidase for Gaucher's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7909160

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.91.8.3176

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference