Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors (Q35157481)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

0 references

1 reference

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Matias G De Vas

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Janel L Kopp

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Claire Heliot

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Maike Sander

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Silvia Cereghini

5

1 reference

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1 March 2020

language of work or name

English

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publication date

1 March 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

number of pages

12

1 reference

inferred from page(s)

published in

Development

1 reference

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1 March 2020

volume

142

1 reference

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1 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

871-882

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

1 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4352981/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.

28 July 2018

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The receptor tyrosine kinase FGFR4 negatively regulates NF-kappaB signaling

28 July 2018

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Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Sox9 coordinates a transcriptional network in pancreatic progenitor cells

28 July 2018

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SOX9 is required for maintenance of the pancreatic progenitor cell pool

28 July 2018

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Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver

28 July 2018

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Hepatocyte nuclear factor-1 beta mutations cause neonatal diabetes and intrauterine growth retardation: support for a critical role of HNF-1? in human pancreatic development

28 July 2018

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Expression of the Notch signaling pathway and effect on exocrine cell proliferation in adult rat pancreas

28 July 2018

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Severe pancreas hypoplasia and multicystic renal dysplasia in two human fetuses carrying novel HNF1beta/MODY5 mutations

28 July 2018

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The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse

28 July 2018

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Identification of target genes of the transcription factor HNF1beta and HNF1alpha in a human embryonic kidney cell line

28 July 2018

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Interactions between hairy/enhancer of split-related proteins and the pancreatic transcription factor Ptf1-p48 modulate function of the PTF1 transcriptional complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Lack of TCF2/vHNF1 in mice leads to pancreas agenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

A transcriptional network in polycystic kidney disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Inhibition of Mist1 homodimer formation induces pancreatic acinar-to-ductal metaplasia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Notch signaling controls multiple steps of pancreatic differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Positional cloning of jcpk/bpk locus of the mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

FGFR4 overexpression in pancreatic cancer is mediated by an intronic enhancer activated by HNF1alpha

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

28 July 2018

1 reference

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The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Regulation of the pancreatic pro-endocrine gene neurogenin3.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Control of endodermal endocrine development by Hes-1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Variant hepatocyte nuclear factor 1 is required for visceral endoderm specification

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Notch signalling controls pancreatic cell differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Impaired glucose homeostasis and neonatal mortality in hepatocyte nuclear factor 3alpha-deficient mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung

28 July 2018

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Hepatocyte nuclear factor 1β controls nephron tubular development

28 July 2018

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A Sox9/Fgf feed-forward loop maintains pancreatic organ identity.

27 September 2018

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Analysis of in vivo transcription factor recruitment by chromatin immunoprecipitation of mouse embryonic kidney

27 September 2018

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Spectrum of clinical diseases caused by disorders of primary cilia

27 September 2018

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Fibroblast growth factor receptor 4 regulates proliferation and antiapoptosis during gastric cancer progression.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Systematic review of TCF2 anomalies in renal cysts and diabetes syndrome/maturity onset diabetes of the young type 5.

27 September 2018

1 reference

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Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

27 September 2018

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Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.

27 September 2018

1 reference

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Ductal malformation and pancreatitis in mice caused by conditional Jag1 deletion

27 September 2018

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Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention

27 September 2018

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HNF-1beta regulates transcription of the PKD modifier gene Kif12

27 September 2018

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Wnt/beta-catenin signaling is required for development of the exocrine pancreas

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Snail2, a mediator of epithelial-mesenchymal transitions, expressed in progenitor cells of the developing endocrine pancreas

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

A vHNF1/TCF2-HNF6 cascade regulates the transcription factor network that controls generation of pancreatic precursor cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Clinical spectrum associated with hepatocyte nuclear factor-1beta mutations.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

The IIIb isoform of fibroblast growth factor receptor 2 is required for proper growth and branching of pancreatic ductal epithelium but not for differentiation of exocrine or endocrine cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Kinesin Family Member 12 Is a Candidate Polycystic Kidney Disease Modifier in the cpk Mouse

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352981

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

16 November 2018

1 reference

12 December 2020

Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis

1 reference

12 December 2020

Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis

1 reference

12 December 2020

Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas

1 reference

12 December 2020

Lack of pancreatic body and tail in HNF1B mutation carriers

1 reference

12 December 2020

Identifiers

DOI

10.1242/DEV.110759

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25715395%20AND%20SRC:MED&resulttype=core&format=json