Maternal age effect: The enigma of Down syndrome and other trisomic conditions (Q35148541)

6 August 2017

1 reference

title

Maternal age effect: the enigma of Down syndrome and other trisomic conditions (English)

1 reference

6 August 2017

Maternal age effect: The enigma of Down syndrome and other trisomic conditions (English)

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

20 November 2023

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1279409

8 September 2022

maternal age

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1279409

8 September 2022

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

20 November 2023

author name string

M. E. Gaulden

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1279409

8 September 2022

language of work or name

English

0 references

publication date

1 December 1992

1 reference

full work available at URL

6 August 2017

20

1 reference

based on heuristic

inferred from page(s)

https://api.elsevier.com/content/article/PII:0165111092900336?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

https://api.elsevier.com/content/article/PII:0165111092900336?httpAccept=text/plain

20 November 2023

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

20 November 2023

1 reference

6 August 2017

296

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6 August 2017

1-2

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6 August 2017

69-88

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Ovum Aging and p H Imbalance as a Cause of Chromosomal Anomalies in the Hamster

6 August 2017

20

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Chemically induced aneuploidy in female germ cells

20 November 2023

21

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Regulation of meiotic maturation in the mammalian oocyte: interplay between exogenous cues and the microtubule cytoskeleton

20 November 2023

22

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Cytoplasmic microtubular dynamics and chromatin organization during mammalian oogenesis and oocyte maturation

20 November 2023

23

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Predivision in human oocytes at meiosis I: a mechanism for trisomy formation in man.

20 November 2023

24

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Molecular mapping of chromosome 21 and the region responsible for Down syndrome

20 November 2023

25

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Parental origin of the extra chromosome in trisomy 21 as indicated by analysis of DNA polymorphisms. Down Syndrome Collaborative Group

20 November 2023

26

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The meiotic stage of nondisjunction in trisomy 21: determination by using DNA polymorphisms

20 November 2023

27

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https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Maternal-age effect in aneuploidy: does altered embryonic selection play a role?

20 November 2023

28

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The genetic control of meiosis

20 November 2023

31

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Cytogenetical observations in mongolism

20 November 2023

34

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https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Mechanisms of aneuploid induction

20 November 2023

35

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Cytogenetics of pregnancy wastage

20 November 2023

36

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Movement and segregation of kinetochores experimentally detached from mammalian chromosomes

20 November 2023

39

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Maternal ageing and aneuploid embryos--evidence from the mouse that biological and not chronological age is the important influence

20 November 2023

40

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Controversy concerning paternal age effect in 47, + 21 Down's syndrome

20 November 2023

41

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The probability of detecting the origin of nondisjunction of autosomal trisomies

20 November 2023

42

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Role of acrocentric cen-pter satellite DNA in Robertsonian translocation and chromosomal non-disjunction

20 November 2023

45

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

A chiasma–hormonal hypothesis relating Down's syndrome and maternal age

20 November 2023

47

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Origin of extra chromosome 21 in 343 families: cytogenetic and molecular approaches

20 November 2023

48

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Cytogenetic analysis of unfertilized oocytes retrieved after treatment with the LHRH analogue, buserelin

20 November 2023

49

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Observations on an Ethnic Classification of Idiots

20 November 2023

50

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Economic costs of aneuploidy: some problems of measurement and conceptualization

20 November 2023

51

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Causes of early embryonic loss in human pregnancy

20 November 2023

52

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Nocodazole sensitivity, age-related aneuploidy, and alterations in the cell cycle during maturation of mouse oocytes

20 November 2023

53

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The CBA mouse as a model for age-related aneuploidy in man: studies of oocyte maturation, spindle formation and chromosome alignment during meiosis

20 November 2023

54

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Accelerated ageing in young mothers of children with Down's syndrome.

20 November 2023

56

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin

20 November 2023

57

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Protocols to establish genotype-phenotype correlations in Down syndrome

20 November 2023

58

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Down syndrome, paternal age, maternal age and birth order

20 November 2023

59

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Reproductive health: a global overview

20 November 2023

62

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

What Is the Evidence That Tumors Are Angiogenesis Dependent?

20 November 2023

64

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The chromosomes in a patient showing both mongolism and the Klinefelter syndrome

20 November 2023

66

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Induction of chromosomal errors

20 November 2023

67

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

A model for the mechanism of aneuploidy involving chromosome displacement

20 November 2023

68

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Hypothesis: some mutagens directly alter specific chromosomal proteins (DNA topoisomerase II and peripheral proteins) to produce chromosome stickiness, which causes chromosome aberrations

20 November 2023

72

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

A model that explains the varying frequency of aneuploid children with maternal age (J-shaped curve) as well as aneuploidy of paternal origin

20 November 2023

73

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Chromosome malsegregation and embryonic lethality induced by treatment of normally ovulated mouse oocytes with nocodazole

20 November 2023

75

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Mongolism, delayed fertilization and human sexual behaviour

20 November 2023

76

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Mechanisms of chromosome orientation revealed by two meiotic mutants in Drosophila melanogaster.

20 November 2023

78

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Chromosome motion in mitosis

20 November 2023

79

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Microtubules in the metaphase-arrested mouse oocyte turn over rapidly

20 November 2023

80

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Oxygen concentration gradient across the ovarian follicular epithelium: model, predictions and implications.

20 November 2023

82

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Alzheimer's disease: the amyloid cascade hypothesis

20 November 2023

86

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

20 November 2023

Trisomy in man

88

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Paternal age and trisomy among spontaneous abortions

20 November 2023

89

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Genetic and molecular analysis of a simple disjunctional system in Drosophila melanogaster

20 November 2023

91

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Chiasma frequency and maternal age in mammals.

20 November 2023

92

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Factual, statistical and logical issues in the search for a paternal age effect for Down syndrome.

20 November 2023

94

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The origin of aneuploidy: bivalent instability and the maternal age effect in trisomy 21 Down syndrome

20 November 2023

95

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Preferential nondisjunction of specific bivalents in oocytes from Djungarian hamsters (Phodopus sungorus) following colchicine treatment

20 November 2023

97

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Maternal health and mongolism

20 November 2023

98

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Alphoid DNA polymorphisms for chromosome 21 can be distinguished from those of chromosome 13 using probes homologous to both

20 November 2023

99

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The somatic chromosomes in mongolism

20 November 2023

100

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Selective advantage of fra (X) heterozygotes compared with mothers of Down syndrome probands?

20 November 2023

102

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Origin of chromosomal abnormalities: Evidence for delayed fertilization in meiotic nondisjunction

20 November 2023

103

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Etiology of nondisjunction: lack of evidence for genetic control

20 November 2023

104

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Origin of nondisjunction in trisomy 21 syndrome: all studies compiled, parental age analysis, and international comparisons.

20 November 2023

105

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Chromosome size-dependent control of meiotic recombination

20 November 2023

106

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Ethanol-induced chromosomal abnormalities at conception

20 November 2023

107

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Separation of meiotic and mitotic effects of claret non-disjunctional on chromosome segregation in Drosophila

20 November 2023

109

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Down syndrome: molecular mapping of the congenital heart disease and duodenal stenosis

20 November 2023

110

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Molecular components of the mitotic spindle

20 November 2023

111

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

A study of the induction of aneuploidy and chromosome aberrations after diazepam, medazepam, midazolam and bromazepam treatment.

20 November 2023

112

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Study of chromosomes of nine children with Down syndrome

20 November 2023

113

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Abnormal chromosomal arrangements in human oocytes

20 November 2023

115

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

On the origin of chromosome anomaly

20 November 2023

116

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Differential sensitivity of mouse oocytes to colchicine-induced aneuploidy

20 November 2023

117

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Structural organization and polymorphism of the alpha satellite DNA sequences of chromosomes 13 and 21 as revealed by pulse field gel electrophoresis

20 November 2023

119

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https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Distribution of aneuploidy in human gametes: comparison between human sperm and oocytes.

20 November 2023

120

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Human Sexual Behaviour, Delayed Fertilization and Down's Syndrome

20 November 2023

121

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https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Trisomy 21: origin of non-disjunction.

20 November 2023

123

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https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Spindle Fiber Action and Chromosome Movement

20 November 2023

124

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https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Clinically recognizable chromosomal abnormalities in newborn infants

20 November 2023

125

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Centrosome and microtubule dynamics during meiotic progression in the mouse oocyte

20 November 2023

126

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Cell signaling, permeability, and microvasculatory changes during antral follicle development in mammals

20 November 2023

129

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Parameters of the human genome

20 November 2023

130

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

A centromere map of the X chromosome from trisomies of maternal origin

20 November 2023

131

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The motor for poleward chromosome movement in anaphase is in or near the kinetochore

20 November 2023

134

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The complete DNA sequence of yeast chromosome III

20 November 2023

135

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Frequency and distribution of aneuploidy in human female gametes.

20 November 2023

137

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Mongolian idiocy (mongolism) and maternal age

20 November 2023

139

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The causes of Down syndrome

20 November 2023

140

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Crossing over and chromosome 21 nondisjunction: a study of 60 families

20 November 2023

141

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Chromosome analysis of human oocytes and embryos: does delayed fertilization increase chromosome imbalance?

20 November 2023

142

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

A Mongol girl with 46 chromosomes

20 November 2023

144

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The structure of the mammalian centromere

20 November 2023

146

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Integrating chromosome structure with function

20 November 2023

147

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The relationship between maternal age and chromosome size in autosomal trisomy

20 November 2023

148

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Mutation frequencies in female mice and the estimation of genetic hazards of radiation in women

20 November 2023

149

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Meiotic arrest and aneuploidy induced by vinblastine in mouse oocytes

20 November 2023

150

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Angiogenesis in the ovary

20 November 2023

151

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Trisomy 21: conference report and 1990 update

20 November 2023

153

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Aging gametes in relation to incidence, gender, and twinning in Down syndrome

20 November 2023

154

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Hormonal characteristics of the human menstrual cycle throughout reproductive life

20 November 2023

155

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Trisomy 21: association between reduced recombination and nondisjunction

20 November 2023

156

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Chromosome Mutations and pH Disturbances

20 November 2023

157

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Trisomies and triploidies in hamster embryos: induction by low-pressure hypoxia and pH imbalances

20 November 2023

158

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Centromeres: an integrated protein/DNA complex required for chromosome movement

20 November 2023

159

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Microinjected centromere [corrected] kinetochore antibodies interfere with chromosome movement in meiotic and mitotic mouse oocytes

20 November 2023

161

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The biological significance of mongolism.

20 November 2023

162

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https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Epidemiologic and toxicologic evidence for chronic health effects and the underlying biologic mechanisms involved in sub-lethal exposures to acidic pollutants

20 November 2023

163

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Attrition of trisomies as a maternal screening device. An explanation of the association of trisomy 21 with maternal age

20 November 2023

165

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

An experimental approach to the analysis of mechanisms of meiotic nondisjunction and anaphase lagging in primary oocytes

20 November 2023

167

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The relation between cell proliferation and the vascular system in a transplanted mouse mammary tumour

20 November 2023

169

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

A genetic linkage map of human chromosome 21: analysis of recombination as a function of sex and age

20 November 2023

171

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Cytogenetic analysis of human oocytes from fertile women

20 November 2023

172

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Oocytes from young and old female mice respond differently to colchicine

20 November 2023

173

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https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The histological structure of some human lung cancers and the possible implications for radiotherapy

20 November 2023

174

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The identification of micronucleated chromosomes: a possible assay for aneuploidy

20 November 2023

175

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Segregation analysis in Alzheimer disease: no evidence for a major gene

20 November 2023

176

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https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Is Down syndrome a modern disease?

20 November 2023

178

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Genetic factors influencing aneuploidy frequency

20 November 2023

179

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

The effect of maternal age on the frequency of trisomy: change in meiosis or in utero selection?

20 November 2023

180

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Evidence for reduced recombination on the nondisjoined chromosomes 21 in Down syndrome

20 November 2023

181

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Centromeres of mammalian chromosomes

20 November 2023

182

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase

20 November 2023

183

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

Evidence for maternal predisposition to chromosome aneuploidy in multiple oocytes of some in vitro fertilization patients

20 November 2023

184

1 reference

https://api.crossref.org/works/10.1016/0165-1110(92)90033-6

20 November 2023

Identifiers

1 reference

release_dudtf5tunfbbvanuneamlea3c4

6 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/dudtf5tunfbbvanuneamlea3c4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference