Interleukin-18 and host defense against infection (Q35147841)

6 August 2017

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title

Interleukin-18 and host defense against infection (English)

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6 August 2017

Giamila Fantuzzi

2

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Charles A. Dinarello

series ordinal

1

object named as

Charles A Dinarello

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PubMed ID

12792854

6 August 2017

language of work or name

English

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publication date

1 June 2003

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Journal of Infectious Diseases

6 August 2017

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6 August 2017

187 Suppl 2

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6 August 2017

S370-84

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Risk and the efficacy of antiinflammatory agents: retrospective and confirmatory studies of sepsis

6 August 2017

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Purification and characterization of the human interleukin-18 receptor

21 January 2018

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T1/ST2 signaling establishes it as a member of an expanding interleukin-1 receptor family

21 January 2018

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Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling

21 January 2018

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

21 January 2018

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MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

21 January 2018

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Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

21 January 2018

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Interleukin 18 stimulates HIV type 1 in monocytic cells

21 January 2018

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Defective interleukin (IL)-18-mediated natural killer and T helper cell type 1 responses in IL-1 receptor-associated kinase (IRAK)-deficient mice

21 January 2018

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IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

21 January 2018

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Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

21 January 2018

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NF-kappa B activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity.

21 January 2018

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The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases)

21 January 2018

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Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein

21 January 2018

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TRAF6 is a signal transducer for interleukin-1

21 January 2018

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21 January 2018

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

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Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

21 January 2018

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Interleukin 1 alpha activates two forms of p54 alpha mitogen-activated protein kinase in rabbit liver

21 January 2018

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Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response

21 January 2018

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Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18

21 January 2018

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A novel IL-18BP ELISA shows elevated serum IL-18BP in sepsis and extensive decrease of free IL-18.

21 January 2018

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Soluble cytokine receptors are present in normal human urine

21 January 2018

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Identification of amino acid residues critical for biological activity in human interleukin-18.

21 January 2018

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Rat interleukin-18 binding protein: cloning, expression, and characterization

21 January 2018

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Site-specific mutations in the mature form of human IL-18 with enhanced biological activity and decreased neutralization by IL-18 binding protein

21 January 2018

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Determination of the functional epitopes of human interleukin-18-binding protein by site-directed mutagenesis

21 January 2018

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Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and IL-18.

21 January 2018

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IL-18 binding and inhibition of interferon gamma induction by human poxvirus-encoded proteins

21 January 2018

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Identification of human and mouse homologs of the MC51L-53L-54L family of secreted glycoproteins encoded by the Molluscum contagiosum poxvirus

21 January 2018

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Orthopoxvirus IL-18 binding proteins: affinities and antagonist activities

21 January 2018

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Correspondence of the functional epitopes of poxvirus and human interleukin-18-binding proteins

21 January 2018

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The combination of soluble IL-18Ralpha and IL-18Rbeta chains inhibits IL-18-induced IFN-gamma.

21 January 2018

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Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells

21 January 2018

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Altered cytokine production in mice lacking P2X(7) receptors

21 January 2018

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Cloning of a new cytokine that induces IFN-gamma production by T cells

21 January 2018

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Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3

21 January 2018

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Defective NK cell activity and Th1 response in IL-18-deficient mice

21 January 2018

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Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

21 January 2018

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Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

21 January 2018

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Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation

21 January 2018

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Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu

21 January 2018

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Interleukin-18 induces acute biphasic reduction in the levels of circulating leukocytes in mice

21 January 2018

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Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1beta

21 January 2018

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Therapeutic effect of neutralizing endogenous IL-18 activity in the collagen-induced model of arthritis

21 January 2018

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Interleukin-1beta converting enzyme (caspase-1) in intestinal inflammation

21 January 2018

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Proinflammatory and antitumor properties of interleukin-18 in the gastrointestinal tract.

21 January 2018

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Blockade of endogenous IL-18 ameliorates TNBS-induced colitis by decreasing local TNF-alpha production in mice

21 January 2018

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IL-18 and IL-12 induce intestinal inflammation and fatty liver in mice in an IFN-gamma dependent manner

21 January 2018

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IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation

21 January 2018

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Primary demyelination in transgenic mice expressing interferon-gamma

21 January 2018

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Interleukin-18 expression after focal ischemia of the rat brain: association with the late-stage inflammatory response.

21 January 2018

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Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat.

21 January 2018

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A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathways

21 January 2018

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IL-18 regulates IL-1beta-dependent hepatic melanoma metastasis via vascular cell adhesion molecule-1.

21 January 2018

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Interleukin 18 restores defective Th1 immunity to Candida albicans in caspase 1-deficient mice

21 January 2018

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21 January 2018

Identifiers

DOI

10.1086/374751

1 reference

6 August 2017

1 reference

PubMed ID

12792854