Overexpression of fatty acid synthase in Middle Eastern epithelial ovarian carcinoma activates AKT and Its inhibition potentiates cisplatin-induced apoptosis. (Q35136665)

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English	Overexpression of fatty acid synthase in Middle Eastern epithelial ovarian carcinoma activates AKT and Its inhibition potentiates cisplatin-induced apoptosis.	scientific article

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26 January 2020

Overexpression of fatty acid synthase in Middle Eastern epithelial ovarian carcinoma activates AKT and Its inhibition potentiates cisplatin-induced apoptosis (English)

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26 January 2020

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ovarian carcinoma

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1

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26 January 2020

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Zeenath Jehan

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26 January 2020

Maqbool Ahmed

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26 January 2020

Aisha Alyan

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26 January 2020

Fouad Al-Dayel

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26 January 2020

Azhar Hussain

6

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26 January 2020

Prashant Bavi

7

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26 January 2020

Khawla S Al-Kuraya

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26 January 2020

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21 March 2011

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26 January 2020

Molecular Medicine

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26 January 2020

17

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26 January 2020

7-8

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26 January 2020

635-645

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26 January 2020

https://scigraph.springernature.com/pub.10.2119/molmed.2011.00046

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Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations

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13 July 2018

Expression of Fatty Acid Synthase Depends on NAC1 and Is Associated with Recurrent Ovarian Serous Carcinomas

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13 July 2018

Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase

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13 July 2018

High prevalence of fatty acid synthase expression in colorectal cancers in Middle Eastern patients and its potential role as a therapeutic target.

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13 July 2018

Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1.

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13 July 2018

Sanguinarine-dependent induction of apoptosis in primary effusion lymphoma cells.

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13 July 2018

Role of phosphatidylinositol 3'-kinase/AKT pathway in diffuse large B-cell lymphoma survival

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146599

13 July 2018

Fatty acid synthase and cancer: new application of an old pathway

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13 July 2018

Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells.

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13 July 2018

Structure and molecular organization of mammalian fatty acid synthase

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13 July 2018

Cancer of the ovary

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13 July 2018

PI3K/Akt and apoptosis: size matters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146599

13 July 2018

Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146599

13 July 2018

Inhibition of Akt kinase signalling and activation of Forkhead are indispensable for upregulation of FasL expression in apoptosis of glioma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146599

13 July 2018

The protein kinase B/Akt signalling pathway in human malignancy

1 reference

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13 July 2018

Current and future potential roles of the platinum drugs in the treatment of ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146599

13 July 2018

Apoptosis and its clinical impact

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146599

13 July 2018

Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146599

13 July 2018

PDK1, one of the missing links in insulin signal transduction?

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13 July 2018

Characterization of anti-peptide antibodies directed towards the automodification domain and apoptotic fragment of poly (ADP-ribose) polymerase

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13 July 2018

Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia.

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13 July 2018

Fatty acid synthase and AKT pathway signaling in a subset of papillary thyroid cancers

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27 September 2018

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146599

27 September 2018

RNA interference-mediated silencing of the fatty acid synthase gene attenuates growth and induces morphological changes and apoptosis of LNCaP prostate cancer cells.

1 reference

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27 September 2018

Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression

1 reference

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27 September 2018

Increased fatty acid synthase activity in non-small cell lung cancer tissue is a weaker predictor of shorter patient survival than increased lipoprotein lipase activity

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00046

31 March 2020

FAS expression inversely correlates with PTEN level in prostate cancer and a PI 3-kinase inhibitor synergizes with FAS siRNA to induce apoptosis

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00046

31 March 2020

Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B

1 reference

https://api.crossref.org/works/10.2119%2FMOLMED.2011.00046

31 March 2020

Impaired Fas response and autoimmunity in Pten+/- mice

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31 March 2020

X-tile: a new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization

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31 March 2020

Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/21442130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymes of the fatty acid synthesis pathway are highly expressed in in situ breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21442130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of fatty acid synthesis delays disease progression in a xenograft model of ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21442130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2119/MOLMED.2011.00046

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Europe PubMed Central

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26 January 2020

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26 January 2020

PubMed publication ID

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26 January 2020

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