A long QT mutation substitutes cholesterol for phosphatidylinositol-4,5-bisphosphate in KCNQ1 channel regulation (Q35134951)

6 August 2017

A long QT mutation substitutes cholesterol for phosphatidylinositol-4,5-bisphosphate in KCNQ1 channel regulation (English)

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6 August 2017

7

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12 June 2020

Isabelle Baró

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12 June 2020

author name string

Fabien C Coyan

1

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12 June 2020

Fayal Abderemane-Ali

2

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12 June 2020

Mohamed Yassine Amarouch

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12 June 2020

Julien Piron

4

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12 June 2020

Jérôme Mordel

5

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Céline S Nicolas

6

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12 June 2020

Jean Mérot

8

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12 June 2020

Céline Marionneau

9

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12 June 2020

Annick Thomas

10

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12 June 2020

Robert Brasseur

11

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12 June 2020

Gildas Loussouarn

13

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12 June 2020

language of work or name

English

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publication date

28 March 2014

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6 August 2017

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12 June 2020

volume

9

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12 June 2020

page(s)

e93255

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12 June 2020

issue

3

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Creative Commons Attribution 4.0 International

12 June 2020

copyright license

start time

28 March 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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KCNE1 enhances phosphatidylinositol 4,5-bisphosphate (PIP2) sensitivity of IKs to modulate channel activity

13 July 2018

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Specificity of cholesterol and analogs to modulate BK channels points to direct sterol-channel protein interactions

13 July 2018

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Phosphatidylinositol-4,5-bisphosphate (PIP(2)) stabilizes the open pore conformation of the Kv11.1 (hERG) channel

13 July 2018

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Impact of KCNE subunits on KCNQ1 (Kv7.1) channel membrane surface targeting

13 July 2018

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13 July 2018

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13 July 2018

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Direct regulation of prokaryotic Kir channel by cholesterol

13 July 2018

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Identification of a C-terminus domain critical for the sensitivity of Kir2.1 to cholesterol

13 July 2018

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Kv11.1 (ERG1) K+ channels localize in cholesterol and sphingolipid enriched membranes and are modulated by membrane cholesterol

13 July 2018

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Protein kinase A modulates PLC-dependent regulation and PIP2-sensitivity of K+ channels

13 July 2018

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IKs response to protein kinase A-dependent KCNQ1 phosphorylation requires direct interaction with microtubules

13 July 2018

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The KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction

13 July 2018

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Distinct detergent-resistant membrane microdomains (lipid rafts) respectively harvest K(+) and water transport systems in brain astroglia

13 July 2018

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13 July 2018

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Regulation of the muscarinic K+ channel by extracellular ATP through membrane phosphatidylinositol 4,5-bisphosphate in guinea-pig atrial myocytes

13 July 2018

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13 July 2018

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Disruption of pancreatic beta-cell lipid rafts modifies Kv2.1 channel gating and insulin exocytosis

13 July 2018

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Phosphatidylinositol-4,5-bisphosphate, PIP2, controls KCNQ1/KCNE1 voltage-gated potassium channels: a functional homology between voltage-gated and inward rectifier K+ channels.

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Probing the effects of membrane cholesterol in the Torpedo californica acetylcholine receptor and the novel lipid-exposed mutation alpha C418W in Xenopus oocytes

13 July 2018

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13 July 2018

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Regulation of ROMK1 channel by protein kinase A via a phosphatidylinositol 4,5-bisphosphate-dependent mechanism

13 July 2018

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13 July 2018

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13 July 2018

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Anionic phospholipids activate ATP-sensitive potassium channels

13 July 2018

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Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains

13 July 2018

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Regulation of cardiac Na+,Ca2+ exchange and KATP potassium channels by PIP2.

13 July 2018

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Mechanism of receptor-mediated modulation of the delayed outward potassium current in guinea-pig ventricular myocytes

13 July 2018

1 reference

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Cholesterol regulation of ion channels: crosstalk in proteins, crosstalk in lipids

13 July 2018

1 reference

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Cholesterol-depleting compounds modulate K+-currents in Drosophila Kenyon cells

21 January 2018

1 reference

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Chronic probucol treatment decreases the slow component of the delayed-rectifier potassium current in CHO cells transfected with KCNQ1 and KCNE1: a novel mechanism of QT prolongation.

21 January 2018

1 reference

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Probucol and the cholesterol synthesis inhibitors simvastatin and triparanol regulate I ks channel function differently.

21 January 2018

1 reference

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PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents

21 January 2018

1 reference

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Impaired KCNQ1-KCNE1 and phosphatidylinositol-4,5-bisphosphate interaction underlies the long QT syndrome

21 January 2018

1 reference

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PKA and PKC partially rescue long QT type 1 phenotype by restoring channel-PIP2 interactions

21 January 2018

1 reference

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Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis

21 January 2018

1 reference

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Characteristic interactions with phosphatidylinositol 4,5-bisphosphate determine regulation of kir channels by diverse modulators.

21 January 2018

1 reference

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HERG K(+) channel activity is regulated by changes in phosphatidyl inositol 4,5-bisphosphate

21 January 2018

1 reference

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Prediction of peptide structure: how far are we?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0093255

Assaying phosphatidylinositol bisphosphate regulation of potassium channels

21 January 2018

1 reference

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Progesterone regulates cardiac repolarization through a nongenomic pathway: an in vitro patch-clamp and computational modeling study

21 January 2018

1 reference

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IMPALA: a simple restraint field to simulate the biological membrane in molecular structure studies.

21 January 2018

1 reference

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Regulation of a heart potassium channel by protein kinase A and C

27 September 2018

1 reference

12 December 2020

Differentiation of lipid-associating helices by use of three-dimensional molecular hydrophobicity potential calculations

1 reference

12 December 2020

KVLQT1 C-terminal missense mutation causes a forme fruste long-QT syndrome

1 reference

12 December 2020

MinK-KvLQT1 fusion proteins, evidence for multiple stoichiometries of the assembled IsK channel

1 reference

12 December 2020

KCNQ1 K+ channel-mediated cardiac channelopathies

1 reference

12 December 2020

Effect of experimental hypercholesterolaemia on K+ channel alpha-subunit mRNA levels in rabbit hearts

1 reference

12 December 2020

KCNE1-KCNQ1 osmoregulation by interaction of phosphatidylinositol-4,5-bisphosphate with Mg2+ and polyamines

1 reference

12 December 2020

Signal transduction during cardiac hypertrophy: the role of G alpha q, PLC beta I, and PKC

1 reference

12 December 2020

Novel mutations in KvLQT1 that affect Iks activation through interactions with Isk

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0093255

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12 June 2020

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