A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors (Q35134137)

6 August 2017

title

A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors (English)

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6 August 2017

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ChEBI release 2020-05-28

Saito A

1

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6 August 2017

Yamashita T

2

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6 August 2017

Mariko Y

3

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6 August 2017

Nosaka Y

4

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6 August 2017

Tsuchiya K

5

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6 August 2017

Ando T

6

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6 August 2017

Suzuki T

7

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6 August 2017

Tsuruo T

8

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6 August 2017

Nakanishi O

9

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6 August 2017

language of work or name

English

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publication date

1 April 1999

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Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

96

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6 August 2017

issue

8

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6 August 2017

page(s)

4592-4597

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Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase

6 August 2017

cites work

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28 July 2018

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Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

28 July 2018

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Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line

28 July 2018

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What's up and down with histone deacetylation and transcription?

28 July 2018

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Histone acetylation: chromatin in action

28 July 2018

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Histone acetylation and chromatin assembly: a single escort, multiple dances?

28 July 2018

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28 July 2018

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Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

28 July 2018

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28 July 2018

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28 July 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

28 July 2018

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Trapoxin, an antitumor cyclic tetrapeptide, is an irreversible inhibitor of mammalian histone deacetylase

28 July 2018

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Relationship between multidrug resistant gene expression and multidrug resistant-reversing effect of MS-209 in various tumor cells

28 July 2018

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Differential expression of the globin genes in human leukemia K562(S) cells induced to differentiate by hemin or butyric acid.

28 July 2018

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Effect of polar organic compounds on leukemic cells. Butyrate-induced partial remission of acute myelogenous leukemia in a child.

28 July 2018

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Properties of an acidic histone-binding protein fraction from cell nuclei. Selective precipitation and deacetylation of histones F2A1 and F3.

28 July 2018

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A direct link between core histone acetylation and transcriptionally active chromatin

28 July 2018

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Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

28 July 2018

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Butyrate-induced cytoarchitectural reorganization of Mallory body-containing rat hepatic tumor cells.

28 July 2018

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Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells

28 July 2018

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Cytoarchitecture of Kirsten sarcoma virus-transformed rat kidney fibroblasts: butyrate-induced reorganization within the actin microfilament network

28 July 2018

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Genetic alterations during colorectal-tumor development

28 July 2018

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Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16377

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16377

Factors responsible for variable reported lineages of HL-60 cells induced to mature with butyric acid.

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16377

On the biological role of histone acetylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16377

Effects of differentiation-inducing agents on maturation of human MCF-7 breast cancer cells

28 July 2018

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Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16377

p52(PAI-1) and actin expression in butyrate-induced flat revertants of v-ras-transformed rat kidney cells

28 July 2018

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p53 function and dysfunction

28 July 2018

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n-Butyrate causes histone modification in HeLa and Friend erythroleukaemia cells

28 July 2018

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Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines

28 July 2018

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Differential elimination of synthetic butyric triglycerides in vivo: a pharmacokinetic study.

27 September 2018

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p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

27 September 2018

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Reversal of multidrug resistance by a novel quinoline derivative, MS-209.

27 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16377

Gelsolin: a candidate for suppressor of human bladder cancer.

27 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16377

Alternative chromatin structure at CpG islands

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.8.4592

Trichostatin A Induces Morphological Changes and Gelsolin Expression by Inhibiting Histone Deacetylase in Human Carcinoma Cell Lines

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.8.4592

Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells

21 January 2018

1 reference

12 December 2020

Butyric monosaccharide ester-induced cell differentiation and anti-tumor activity in mice. Importance of their prolonged biological effect for clinical applications in cancer therapy

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12 December 2020

Affinity chromatographic purification of nucleosomes containing transcriptionally active DNA sequences

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12 December 2020

Clinical pharmacology of sodium butyrate in patients with acute leukemia

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12 December 2020

Effects of sodium butyrate and dimethylsulfoxide on biochemical properties of human colon cancer cells

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12 December 2020

Histone deacetylase from calf thymus

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12 December 2020

Multiplicity of histone deacetylase from calf thymus

1 reference

12 December 2020

Human pancreatic carcinomas and cell lines reveal frequent and multiple alterations in the p53 and Rb-1 tumor-suppressor genes

1 reference

12 December 2020

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1 reference

12 December 2020

Differential effects of sodium butyrate, dimethyl sulfoxide, and retinoic acid on membrane-associated antigen, enzymes, and glycoproteins of human rectal adenocarcinoma cells

1 reference

12 December 2020

Sodium butyrate induces differentiation in breast cancer cell lines expressing the estrogen receptor

1 reference

12 December 2020

Derivatives of butyric acid as potential anti-neoplastic agents

1 reference

12 December 2020

Potentiation of the antitumor activity by a novel quinoline compound, MS-209, in multidrug-resistant solid tumor cell lines

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.96.8.4592

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6 August 2017

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6 August 2017

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