In vitro assay of cytotoxicity with cultured liver: accomplishments and possibilities (Q35132506)

6 August 2017

2 references

7 October 2019

14 September 2020

In vitro assay of cytotoxicity with cultured liver: accomplishments and possibilities (English)

1 reference

6 August 2017

main subject

human digestive system

1 reference

7 October 2019

1 reference

14 September 2020

J. W. Grisham

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A363407

26 June 2022

R. K. Charlton

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A363407

26 June 2022

D. G. Kaufman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A363407

26 June 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=363407

26 June 2022

publication date

1 August 1978

3 references

full work available at URL

6 August 2017

7 October 2019

14 September 2020

https://europepmc.org/articles/PMC1637199

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A363407

https://europepmc.org/articles/PMC1637199?pdf=render

26 June 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A363407

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1637199

26 June 2022

1 reference

Environmental Health Perspectives

8 April 2023

published in

3 references

6 August 2017

7 October 2019

14 September 2020

25

1 reference

6 August 2017

page(s)

161-171

1 reference

Tissue culture of human embryo liver cells and the cytotoxicity of aflatoxin B1.

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

The effect of heliotrine, a pyrrolizidine alkaloid, on human liver cells in culture

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

In vitro malignant transformation of cells derived from rat liver by means of aflatoxin B1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Tissue culture in the study of the effects of drugs

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Isolation and long-term cell culture of epithelial-like cells from rat liver

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Induction of morphological changes in human embryo liver cells by the pyrrolizidine alkaloid lasiocarpine

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

The effects of lasiocarpine, retrorsine and retronecine pyrrole on human embryo lung and liver cells in culture

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Production of Albumin and Other Serum Proteins by Clonal Cultures of Normal Human Liver

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Use of cell culture in pharmacology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Present trends in cancer epidemiology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

The circumfusion system for multipurposeculture chambers. II. The protracted maintenance of differentiation of fetal and newborn mouse liver in vitro

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

The effects of aflatoxins on human embryo liver cells in culture

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Localization of benzo(a)pyrene-3H and alterations in nuclear chromatin caused by benzo(a)pyrene-ferric oxide in the hamster respiratory epithelium

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Malignant Transformation in vitro of Rat Liver Cells by Dimethylnitrosamine and N-Methyl-N′-nitro-N-Nitrosoguanidine

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Induction of benzpyrene hydroxylase in fetal liver explants by flavones and phenobarbital

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Carcinoma after malignant conversion in vitro of epithelial-like cells from rat liver following exposure to chemical carcinogens

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Carcinogenesis In Tissue Culture. XIV. Malignant Transformation of Rat Liver Parenchymal Cells Treated With 4-Nitroquinoline 1-Oxide In Tissue Culture234

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Pyruvate kinase, hexokinase, and aldolase isozymes in rat liver cells in culture.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Long term cell culture of rat liver epithelial cells retaining some hepatic functions.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Parenchymal cells from adult rat liver in nonproliferating monolayer culture. II. Ultrastructural studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Parenchymal cells from adult rat liver in nonproliferating monolayer culture. I. Functional studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

The protective effect of estradiol-17 beta against polycyclic hydrocarbon cytotoxicity.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Neoplastic transformation in vitro of a clone of adult liver epithelial cells into differentiated hepatoma-like cells under conditions of nutritional stress

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Studies on primary cultures of differentiated fetal liver cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Carcinogenesis in tissue culture. 8. Spontaneous malignant transformation of rat liver cells in long-term culture.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Marmoset liver organ culture infected with herpes virus

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Long-term cultivation of two diploid epithelial cell lines derived from normal rat liver cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Liver cell differentiation in a chemically defined medium. Morphologic and enzymatic comparisons of in utero rat liver and liver rudiment grown in organ culture

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Quantitative studies of in vitro transformation by chemical carcinogens.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

The effect of tetracycline on human liver cells in culture

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

The WIRL-3 rat liver cell lines and their transformed derivatives.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Induction of hepatocarcinoma in vivo with fetal mouse liver cells spontaneously transformed in culture and isolation of a type C RNA virus from the carcinoma cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Aryl hydrocarbon hydroxylase induction in mammalian liver cell culture. II. Effects of actinomycin D and cycloheximide on induction processes by phenobarbital or polycyclic hydrocarbons

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

A comparison of the 8-azaguanine and ouabain-resistance systems for the selection of induced mutant Chinese hamster cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

A diploid rat liver cell culture. III. Characterization of the heteroploid morphological variants which develop with time in culture

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Production of epithelial and mesenchymal tumours with rat liver cells transformedin vitro

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Properties and malignant transformation of established rat liver parenchymal cells in culture

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Albumin, fibrinogen and transferrin synthesis in isolated rat hepatocyte suspensions. A model for the study of plasma protein synthesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Toxicity of tricyclic antidepressants to isolated rat hepatocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Maintenance of cytochrome P-450 and metabolism of aflatoxin B1 in primary hepatocyte cultures

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

The use of liver epithelial cultures for the study of chemical carcinogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Detection of chemical carcinogens by unscheduled DNA synthesis in rat liver primary cell cultures

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Contribution of the Environment to Cancer Incidence: An Epidemiologic Exercise

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Carcinogen-induced dna repair in primary rat liver cell cultures; a possible screen for chemical carcinogens

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Chapter 31 Primary and Long-Term Culture of Adult Rat Liver Epithelial Cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Benzo(alpha)pyrene effects on mouse epithelial cells in culture

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Interaction of chemical carcinogens and drug-metabolizing enzymes in primary cultures of hepatic cells from the rat

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Ratliver cells in culture: Effect of storage, long-term culture, and transformation on some enzyme levels

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Isolated Mammalian Hepatocytes in Culture

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1637199

Effect of cobalt on synthesis of heme and cytochrome P-450 in the liver. Studies of adult rat hepatocytes in primary monolayer culture and in vivo

13 July 2018

1 reference

12 December 2020

Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion

1 reference

12 December 2020

Aryl hydrocarbon (benzo(a)pyrene) hydroxylase induction in rat liver cells in culture

1 reference

12 December 2020

Two forms of repair in the DNA of human cells damaged by chemical carcinogens and mutagens

1 reference

12 December 2020

Ultrastructural and functional studies of cultured hepatocytes

1 reference

12 December 2020

Comparison of the genetic activity of dimethylnitrosamine, ethyl methanesulfonate, 2-acetylaminofluorene and ICR-170 in Saccharomyces cerevisiae strains D3, D4 and D5 using in vitro assays with and without metabolic activation

1 reference

12 December 2020

Cytochrome P-450 induction by phenobarbital and 3-methylcholanthrene in primary cultures of hepatocytes

1 reference

12 December 2020

Conditions affecting primary cell cultures of functional adult rat hepatocytes. 1. The effect of insulin

1 reference

12 December 2020

Adult liver parenchymal cells in primary culture characteristics and cell recognition standards

1 reference

12 December 2020

A diploid rat liver cell culture. 1. Characterization and sensitivity to aflatoxin B1

1 reference

12 December 2020

Procarcinogen activation and hormonal control of cell proliferation in differentiated primary adult rat liver cell cultures

1 reference

12 December 2020

Metabolism of benzo(a)pyrene with isolated hepatocytes and the formation and degradation of DNA-binding derivatives

1 reference

12 December 2020

A METHOD OF CULTIVATING MORPHOLOGICALLY HIGHLY DIFFERENTIATED LIVER EPITHELIUM IN VITRO

1 reference

12 December 2020

Metabolism of rat liver cells cultured in suspension: insulin and glucagon effects on glycogen level

1 reference

12 December 2020

Explant culture of rat liver. I. Method, morphology, and cytogenesis

1 reference

12 December 2020

Metabolic and virologic studies in primate liver organ cultures

1 reference

12 December 2020

Tyrosine transaminase induction by dexamethasone in a new rat liver cell line

1 reference

12 December 2020

Proliferation kinetics of hepatocytes in primary cultures of liver

1 reference

12 December 2020

Effects of some sulfonylurea derivatives on the rat liver in organ-typic culture. II. Study of the arginase activity

1 reference

12 December 2020

Maintenance of viable cells in an organ culture of mature rat liver

1 reference

12 December 2020

In vitro stimulation of rat liver cells by homologous partial hepatectomy serum

1 reference

12 December 2020

Cultures from adult rat liver cells. I. Establishment of monolayer cell-cultures from normal liver

1 reference

12 December 2020

Carcinomas from rat liver cells transformed spontaneously in culture

1 reference

12 December 2020

Influence of Cortisol on Glycogen Synthesis and Gluconeogenesis in Fetal Rat Liver in Organ Culture

1 reference

12 December 2020

Early changes in chromosomal number and structure after treatment of fetal hamster cultures with transforming doses of polycyclic hydrocarbons

1 reference

12 December 2020

Morphological and biochemical observations on mammalian liver cells in culture. Isolation of a clonal strain from rat liver

1 reference

12 December 2020

Isolated rat hepatocytes as a model to study drug metabolism: Dose-dependent metabolism of diphenylhydantoin

1 reference

12 December 2020

Insulin and hydrocortisone effects on viability and glycogen stores of postnatal rat liver organ culture

1 reference

12 December 2020

Effect of insulin on glycogen synthesis in fetal rat liver in organ culture

19

1 reference

Primary culture of parenchymal liver cells on collagen membranes. Morphological and biochemical observations

8 April 2023

31

1 reference

Study of hepatocyte function in cell culture

8 April 2023

39

1 reference

Intercellular communication and tissue growth : IV. Conductance of membrane junctions of normal and cancerous cells in culture

8 April 2023

51

1 reference

The direct toxicity of alpha-naphthylisothiocyanate in cell culture

8 April 2023

97

1 reference

A diploid rat liver cell culture. 2. Effect of aflatoxin B1 on ribonucleic acid synthesis

8 April 2023

100

1 reference

8 April 2023

Identifiers

DOI

10.1289/EHP.7825161

1 reference

6 August 2017

1 reference

6 August 2017

1 reference