Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase (Q35131087)

6 August 2017

Insights into the mechanism of a G-quadruplex-unwinding DEAH-box helicase (English)

1 reference

6 August 2017

Michael C Chen

1

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author name string

Pierre Murat

2

1 reference

6 August 2017

Keren Abecassis

3

1 reference

6 August 2017

Adrian R Ferré-D'Amaré

4

1 reference

6 August 2017

Shankar Balasubramanian

5

1 reference

6 August 2017

language of work or name

English

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publication date

4 February 2015

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6 August 2017

Nucleic Acids Research

1 reference

6 August 2017

43

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6 August 2017

2223-2231

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6 August 2017

4

1 reference

Creative Commons Attribution 4.0 International

6 August 2017

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4344499/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1.

28 July 2018

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Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells.

28 July 2018

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Pif1 family helicases suppress genome instability at G-quadruplex motifs

28 July 2018

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Quantitative visualization of DNA G-quadruplex structures in human cells

28 July 2018

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Dda helicase tightly couples translocation on single-stranded DNA to unwinding of duplex DNA: Dda is an optimally active helicase

28 July 2018

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28 July 2018

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Yin Yang 1 contains G-quadruplex structures in its promoter and 5'-UTR and its expression is modulated by G4 resolvase 1

28 July 2018

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From unwinding to clamping - the DEAD box RNA helicase family

28 July 2018

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G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA

28 July 2018

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Human DHX9 helicase preferentially unwinds RNA-containing displacement loops (R-loops) and G-quadruplexes

28 July 2018

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Human DHX9 helicase unwinds triple-helical DNA structures

28 July 2018

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Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU

28 July 2018

1 reference

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Riboswitch function: flipping the switch or tuning the dimmer?

28 July 2018

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Active and passive mechanisms of helicases

28 July 2018

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Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae

28 July 2018

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28 July 2018

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ATP hydrolysis is required for DEAD-box protein recycling but not for duplex unwinding

28 July 2018

1 reference

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G4 resolvase 1 binds both DNA and RNA tetramolecular quadruplex with high affinity and is the major source of tetramolecular quadruplex G4-DNA and G4-RNA resolving activity in HeLa cell lysates

28 July 2018

1 reference

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FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability

28 July 2018

1 reference

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DEAD-box proteins unwind duplexes by local strand separation

28 July 2018

1 reference

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Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action

28 July 2018

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An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation

28 July 2018

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Dead-box proteins: a family affair--active and passive players in RNP-remodeling

28 July 2018

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The DEAD-box protein family of RNA helicases

28 July 2018

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ATP- and ADP-dependent modulation of RNA unwinding and strand annealing activities by the DEAD-box protein DED1.

28 July 2018

1 reference

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The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates

28 July 2018

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Kinetics of tetramolecular quadruplexes

28 July 2018

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28 July 2018

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Substructure solution with SHELXD

28 July 2018

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G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition

28 July 2018

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eIF4A: the godfather of the DEAD box helicases

28 July 2018

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Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

28 July 2018

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Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands.

28 July 2018

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Inhibition of the Bloom's and Werner's syndrome helicases by G-quadruplex interacting ligands

28 July 2018

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X-ray analysis of an RNA tetraplex (UGGGGU)4 with divalent Sr2+ ions at subatomic resolution (0.61 A)

28 July 2018

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DExD/H box RNA helicases: from generic motors to specific dissociation functions

28 July 2018

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Further characterization of the helicase activity of eIF4A. Substrate specificity

28 July 2018

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Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344499

Quadruplex DNA formation in a region of the tRNA gene supF associated with hydrogen peroxide mediated mutations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344499

Translation initiation on mammalian mRNAs with structured 5'UTRs requires DExH-box protein DHX29.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344499

DEAD-box proteins can completely separate an RNA duplex using a single ATP.

27 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344499

A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344499

Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344499

Studies on three E. coli DEAD-box helicases point to an unwinding mechanism different from that of model DNA helicases.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344499

Processing of X-ray diffraction data collected in oscillation mode

27 September 2018

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https://api.crossref.org/works/10.1093%2FNAR%2FGKV051

Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds

21 January 2018

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https://api.crossref.org/works/10.1093%2FNAR%2FGKV051

Topological Characterization of Nucleic Acid G-Quadruplexes by UV Absorption and Circular Dichroism

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4344499

Biochemical and kinetic characterization of the RNA helicase activity of eukaryotic initiation factor 4A

8 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25653156

12 December 2020

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Inhibition of DNA helicase II unwinding and ATPase activities by DNA-interacting ligands. Kinetics and specificity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25653156

12 December 2020

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Dynamic roles for G4 DNA in the biology of eukaryotic cells

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25653156

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/NAR/GKV051

1 reference

6 August 2017

1 reference

6 August 2017

1 reference