Mismatch repair proficiency and in vitro response to 5-fluorouracil (Q35129256)

6 August 2017

Mismatch repair proficiency and in vitro response to 5-fluorouracil (English)

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6 August 2017

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J M Carethers

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6 August 2017

D P Chauhan

2

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6 August 2017

D Fink

3

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6 August 2017

S Nebel

4

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6 August 2017

R S Bresalier

5

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6 August 2017

S B Howell

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6 August 2017

C R Boland

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6 August 2017

language of work or name

English

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publication date

1 July 1999

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6 August 2017

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6 August 2017

117

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6 August 2017

123-131

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6 August 2017

1

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The effect of different chemotherapeutic agents on the enrichment of DNA mismatch repair-deficient tumour cells

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Differential induction of c-Jun NH2-terminal kinase and c-Abl kinase in DNA mismatch repair-proficient and -deficient cells exposed to cisplatin.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

DNA mismatch repair in mammals: role in disease and meiosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

DNA repair and colorectal cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

The role of DNA mismatch repair in platinum drug resistance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

hMutSbeta, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Transcription-coupled repair deficiency and mutations in human mismatch repair genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Microsatellite instability in cancer of the proximal colon

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Clues to the pathogenesis of familial colorectal cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Mutation of a mutL homolog in hereditary colon cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Genetic instability in human ovarian cancer cell lines.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Mutations of GTBP in genetically unstable cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Genetic instability occurs in the majority of young patients with colorectal cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Fluorinated pyrimidines as tight-binding inhibitors of thymidylate synthetase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Characterization of quantitative mucin variants from a human colon cancer cell line.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Cell cycle perturbation and cell death after exposure of a human lymphoblastoid cell strain to N-methyl-N'-nitro-N-nitrosoguanidine.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Metabolism and mechanism of action of 5-fluorouracil

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Self-destruction and tolerance in resistance of mammalian cells to alkylation damage

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

In vitro enhancement of fluoropyrimidine-induced cytotoxicity by leucovorin in colorectal and gastric carcinoma cell lines but not in non-small-cell lung carcinoma cell lines

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Dissociation of 5-fluorouracil-induced DNA fragmentation from either its incorporation into DNA or its cytotoxicity in murine T-lymphoma (S-49) cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Frameshift mutator mutations

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4343206

Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

16 November 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970558-5

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970558-5

Chemotherapy for colorectal cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970558-5

Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970558-5

Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970558-5

DNA mismatch binding and incision at modified guanine bases by extracts of mammalian cells: implications for tolerance to DNA methylation damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970558-5

Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2899%2970558-5

Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer

7 January 2021

1 reference

12 December 2020

DNA lesions in human neoplastic cells and cytotoxicity of 5-fluoropyrimidines

1 reference

12 December 2020

Mechanism for exclusion of 5-fluorouracil from DNA

1 reference

12 December 2020

5-Fluorouracil incorporation in DNA of human breast carcinoma cells

1 reference

12 December 2020

The role of deoxyuridine triphosphate nucleotidohydrolase, uracil-DNA glycosylase, and DNA polymerase alpha in the metabolism of FUdR in human tumor cells

1 reference

12 December 2020

10.1016/S0016-5085(99)70558-5

Identifiers

DOI

1 reference

6 August 2017

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6 August 2017

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