The stem cell factor/c-kit receptor pathway enhances proliferation and invasion of pancreatic cancer cells (Q35126922)

6 August 2017

The stem cell factor/c-kit receptor pathway enhances proliferation and invasion of pancreatic cancer cells (English)

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6 August 2017

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Akira Yasuda

1

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6 August 2017

Hirozumi Sawai

2

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6 August 2017

Hiroki Takahashi

3

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6 August 2017

Nobuo Ochi

4

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6 August 2017

Yoichi Matsuo

5

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6 August 2017

Hitoshi Funahashi

6

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6 August 2017

Mikinori Sato

7

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6 August 2017

Yuji Okada

8

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6 August 2017

Hiromitsu Takeyama

9

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6 August 2017

Tadao Manabe

10

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6 August 2017

18 October 2006

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6 August 2017

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6 August 2017

5

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6 August 2017

46

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https://scigraph.springernature.com/pub.10.1186/1476-4598-5-46

6 August 2017

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cites work

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STI571 (Glivec) suppresses the expression of vascular endothelial growth factor in the gastrointestinal stromal tumor cell line, GIST-T1.

28 July 2018

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Front-line therapy of advanced pancreatic cancer

28 July 2018

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Gastrointestinal stromal tumors and the evolution of targeted therapy.

28 July 2018

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Imatinib inhibits proliferation of Ewing tumor cells mediated by the stem cell factor/KIT receptor pathway, and sensitizes cells to vincristine and doxorubicin-induced apoptosis.

28 July 2018

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Effects of STI571 (gleevec) on pancreatic cancer cell growth

28 July 2018

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HER-2/neu and CD117 (C-kit) overexpression in hepatocellular and pancreatic carcinoma.

28 July 2018

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Analysis of c-kit protein expression in small-cell lung carcinoma and its implication for prognosis

28 July 2018

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The stem cell factor-c-kit system and mast cells in human pancreatic cancer

28 July 2018

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A novel approach in the treatment of cancer: targeting the epidermal growth factor receptor.

28 July 2018

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Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors

28 July 2018

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The biology of stem cell factor and its receptor C-kit

28 July 2018

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Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

28 July 2018

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

28 July 2018

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Tyrosine kinase inhibition: an approach to drug development

28 July 2018

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Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product

28 July 2018

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Recombinant human stem cell factor mediates chemotaxis of small-cell lung cancer cell lines aberrantly expressing the c-kit protooncogene.

28 July 2018

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Soluble stem cell factor in human serum

28 July 2018

1 reference

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Transformation of thyroid epithelium is associated with loss of c-kit receptor

28 July 2018

1 reference

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W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity

28 July 2018

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Expression of stem cell factor and c-kit in human neuroblastoma. The Children's Cancer Group.

28 July 2018

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Growth factors and their action in vivo and in vitro

28 July 2018

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Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand

28 July 2018

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Steel locus defines new multipotent growth factor

28 July 2018

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Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

Activation of the human c-kit product by ligand-induced dimerization mediates circular actin reorganization and chemotaxis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

Candidate ligand for the c-kit transmembrane kinase receptor: KL, a fibroblast derived growth factor stimulates mast cells and erythroid progenitors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

Identification of a ligand for the c-kit proto-oncogene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

Signal transduction from cell surface to nucleus in development and disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

Decreased production of mast cells in S1/S1d anemic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

Immunohistochemical expression of receptor-tyrosine kinase c-kit protein and TGF-beta1 in invasive ductal carcinoma of the pancreas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

Prognostic significance of c-kit mutation in localized gastrointestinal stromal tumors.

27 September 2018

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Inhibition of cell survival and invasive potential of colorectal carcinoma cells by the tyrosine kinase inhibitor STI571.

27 September 2018

1 reference

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Immunohistochemical expression of receptor-tyrosine kinase c-kit protein in invasive ductal carcinoma of the pancreas

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

Gastrointestinal stromal tumor workshop.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

Autocrine growth of small cell lung cancer mediated by coexpression of c-kit and stem cell factor.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1634869

c-kit point mutation of extracellular domain in patients with myeloproliferative disorders

27 September 2018

1 reference

12 December 2020

Expression of the c-kit gene product in normal and neoplastic mast cells but not in neoplastic basophil/mast cell precursors from chronic myelogenous leukaemia

1 reference

12 December 2020

Growth stimulation of colorectal carcinoma cells via the c-kit receptor is inhibited by TGF-beta 1

1 reference

12 December 2020

Plasma levels and production of soluble stem cell factor by marrow stromal cells in patients with aplastic anaemia

1 reference

12 December 2020

Elevated SCF levels in the serum of patients with chronic renal failure

1 reference

12 December 2020

Prognostic significance of the expression of vascular endothelial growth factor (VEGF) and VEGF-C in gastric carcinoma

1 reference

12 December 2020

Breast cancer is associated with loss of the c-kit oncogene product

1 reference

12 December 2020

Identifiers

DOI

10.1186/1476-4598-5-46

1 reference

Dimensions Publication ID

6 August 2017

0 references

1 reference

6 August 2017

1 reference