Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages (Q35125206)

6 August 2017

Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages (English)

1 reference

Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

6 August 2017

1 reference

1 reference

RAB5A, member RAS oncogene family

1 reference

Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

1 reference

RAB31, member RAS oncogene family

1 reference

Lin Luo

3

0 references

Adam Alexander Wall

object named as

Adam A Wall

series ordinal

2

0 references

Jennifer Stow

object named as

Jennifer L Stow

series ordinal

4

0 references

author name string

Jeremy C Yeo

series ordinal

1

1 reference

6 August 2017

7 January 2015

1 reference

6 August 2017

14

1 reference

Molecular Biology of the Cell

inferred from page(s)

published in

1 reference

6 August 2017

26

1 reference

6 August 2017

952-965

1 reference

6 August 2017

5

1 reference

PubMed ID

25568335

describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4342030/fullTextXML

inferred from PubMed Central ID database lookup

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13 July 2018

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Membrane Curvature Protein Exhibits Interdomain Flexibility and Binds a Small GTPase

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13 July 2018

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Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells

13 July 2018

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Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling

13 July 2018

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13 July 2018

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Pathogens and polymers: microbe-host interactions illuminate the cytoskeleton

13 July 2018

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The cell biology of phagocytosis

13 July 2018

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Biochemical characterization of APPL endosomes: the role of annexin A2 in APPL membrane recruitment

13 July 2018

1 reference

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Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes

13 July 2018

1 reference

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Kinesin 5B is necessary for delivery of membrane and receptors during FcγR-mediated phagocytosis

13 July 2018

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Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets

13 July 2018

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APPL proteins FRET at the BAR: direct observation of APPL1 and APPL2 BAR domain-mediated interactions on cell membranes using FRET microscopy

13 July 2018

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Imaging signal transduction during phagocytosis: phospholipids, surface charge, and electrostatic interactions

13 July 2018

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Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development

13 July 2018

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Rab35 mediates transport of Cdc42 and Rac1 to the plasma membrane during phagocytosis

13 July 2018

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Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts

13 July 2018

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Interaction of Rab31 and OCRL-1 in oligodendrocytes: its role in transport of mannose 6-phosphate receptors

13 July 2018

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Interplay between Akt and p38 MAPK pathways in the regulation of renal tubular cell apoptosis associated with diabetic nephropathy

13 July 2018

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Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells

13 July 2018

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Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells

13 July 2018

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Specific role of phosphoinositide 3-kinase p110alpha in the regulation of phagocytosis and pinocytosis in macrophages

13 July 2018

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A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes

13 July 2018

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Membrane ruffles capture C3bi-opsonized particles in activated macrophages

13 July 2018

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A pathway for phagosome maturation during engulfment of apoptotic cells

13 July 2018

1 reference

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Modulation of the phagosome proteome by interferon-gamma.

13 July 2018

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Membrane targeting by APPL1 and APPL2: dynamic scaffolds that oligomerize and bind phosphoinositides

13 July 2018

1 reference

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A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

13 July 2018

1 reference

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Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5

13 July 2018

1 reference

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Monocyte p110alpha phosphatidylinositol 3-kinase regulates phagocytosis, the phagocyte oxidase, and cytokine production

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes

13 July 2018

1 reference

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APPL1, APPL2, Akt2 and FOXO1a interact with FSHR in a potential signaling complex

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

A role for the phagosome in cytokine secretion

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Vps29 has a phosphoesterase fold that acts as a protein interaction scaffold for retromer assembly

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

The coordination of signaling during Fc receptor-mediated phagocytosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment

13 July 2018

1 reference

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Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Class I phosphoinositide 3-kinase p110beta is required for apoptotic cell and Fcgamma receptor-mediated phagocytosis by macrophages

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Role of rRAB22b, an oligodendrocyte protein, in regulation of transport of vesicles from trans Golgi to endocytic compartments

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Localization and post-Golgi trafficking of tumor necrosis factor-alpha in macrophages

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

A Rab11-containing rapidly recycling compartment in macrophages that promotes phagocytosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

A requirement for phosphatidylinositol 3-kinase in pseudopod extension

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Kinetics of interaction of Rab5 and Rab7 with nucleotides and magnesium ions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Actin cytoskeleton reorganization by Syk regulates Fcγ receptor responsiveness by increasing its lateral mobility and clustering

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Adaptor protein APPL1 couples synaptic NMDA receptor with neuronal prosurvival phosphatidylinositol 3-kinase/Akt pathway

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Regulation of phagocytosis in Dictyostelium by the inositol 5-phosphatase OCRL homolog Dd5P4.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Localised PtdIns(3,4,5)P3 or PtdIns(3,4)P2 at the phagocytic cup is required for both phagosome closure and Ca2+ signalling in HL60 neutrophils.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Phosphoinositide-3-kinase-independent contractile activities associated with Fcgamma-receptor-mediated phagocytosis and macropinocytosis in macrophages

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4342030

Rab35 regulates phagosome formation through recruitment of ACAP2 in macrophages during Fc R-mediated phagocytosis

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1091%2FMBC.E14-10-1457

Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25568335

12 December 2020

inferred from PubMed ID database lookup

Regulation of bone-marrow macrophage proliferation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25568335

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1091/MBC.E14-10-1457

1 reference

6 August 2017

1 reference

6 August 2017

1 reference

PubMed ID

25568335