Serotonin 5-HT₂ receptor activation prevents allergic asthma in a mouse model (Q35115841)

6 August 2017

Serotonin 5-HT₂ receptor activation prevents allergic asthma in a mouse model (English)

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6 August 2017

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9 June 2020

Stephania A Cormier

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Charles D Nichols

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9 June 2020

author name string

Felix Nau

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9 June 2020

Justin Miller

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9 June 2020

Terry Ahlert

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9 June 2020

Bangning Yu

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9 June 2020

Kyle I Happel

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9 June 2020

publication date

1 January 2015

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American Journal of Physiology - Lung Cellular and Molecular Physiology

6 August 2017

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9 June 2020

volume

308

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9 June 2020

page(s)

L191-8

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9 June 2020

issue

2

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Serotonin 5-HT2A receptor activation blocks TNF-α mediated inflammation in vivo

9 June 2020

cites work

1 reference

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Regulation of serotonin-induced trafficking and migration of eosinophils

9 July 2018

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Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model

9 July 2018

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Environmentally persistent free radicals induce airway hyperresponsiveness in neonatal rat lungs.

9 July 2018

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Regulation of antigen-specific CTL and Th1 cell activation through 5-Hydroxytryptamine 2A receptor

9 July 2018

1 reference

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Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a ß-arrestin2/Src/Akt signaling complex in vivo

9 July 2018

1 reference

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Inchoate CD8+ T cell responses in neonatal mice permit influenza-induced persistent pulmonary dysfunction

9 July 2018

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Serotonin 5-hydroxytryptamine(2A) receptor activation suppresses tumor necrosis factor-alpha-induced inflammation with extraordinary potency

9 July 2018

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9 July 2018

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Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo

9 July 2018

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GPCR functional selectivity has therapeutic impact

9 July 2018

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IL-1beta induces murine airway 5-HT2A receptor hyperresponsiveness via a non-transcriptional MAPK-dependent mechanism

9 July 2018

1 reference

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Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors

9 July 2018

1 reference

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Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor

9 July 2018

1 reference

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Contractility and Ca2+ signaling of smooth muscle cells in different generations of mouse airways

9 July 2018

1 reference

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Exposure of neonates to respiratory syncytial virus is critical in determining subsequent airway response in adults

9 July 2018

1 reference

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A role for airway remodeling during respiratory syncytial virus infection

9 July 2018

1 reference

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Functions of 5-HT2A receptor and its antagonists in the cardiovascular system

9 July 2018

1 reference

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Anti-inflammatory cytokines in asthma and allergy: interleukin-10, interleukin-12, interferon-gamma

9 July 2018

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9 July 2018

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mRNA expression of serotonin receptors in cells of the immune tissues of the rat.

9 July 2018

1 reference

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Molecular pathology of allergic disease: I: lower airway disease

9 July 2018

1 reference

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Chemokines and allergic disease.

9 July 2018

1 reference

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Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

9 July 2018

1 reference

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The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness

9 July 2018

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9 July 2018

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Chemokines--chemotactic cytokines that mediate inflammation

9 July 2018

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Gene transfer for cytokine functional studies in the lung: the multifunctional role of GM-CSF in pulmonary inflammation.

9 July 2018

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Eosinophils and allergy in asthma.

9 July 2018

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Secretion of the eosinophil-active cytokines interleukin-5, granulocyte/macrophage colony-stimulating factor and interleukin-3 by bronchoalveolar lavage CD4+ and CD8+ T cell lines in atopic asthmatics, and atopic and non-atopic controls

9 July 2018

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The pathobiology of bronchial asthma

9 July 2018

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Cytokines in symptomatic asthma airways

9 July 2018

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Serotonin activates murine alveolar macrophages through 5-HT2C receptors

9 July 2018

1 reference

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Increased muscarinic receptor activity of airway smooth muscle isolated from a mouse model of allergic asthma

27 September 2018

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Role of 5-HT2A, 5-HT4 and 5-HT7 receptors in the antigen-induced airway hyperresponsiveness in guinea-pigs.

27 September 2018

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Airway smooth muscle relaxation induced by 5-HT(2A) receptors: role of Na(+)/K(+)-ATPase pump and Ca(2+)-activated K(+) channels.

27 September 2018

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Interleukin-13 in asthma pathogenesis.

27 September 2018

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Peroxisome proliferator-activated receptor gamma is expressed in airways and inhibits features of airway remodeling in a mouse asthma model

27 September 2018

1 reference

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A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma

27 September 2018

1 reference

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Discriminative stimulus properties of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane [(+/-)DOI] in C57BL/6J mice

27 September 2018

1 reference

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IgE-dependent mast cell activation potentiates airway responses in murine asthma models

27 September 2018

1 reference

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Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma

27 September 2018

1 reference

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Increases in airway eosinophils and interleukin-5 with minimal bronchoconstriction during repeated low-dose allergen challenge in atopic asthmatics.

27 September 2018

1 reference

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Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1

27 September 2018

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Proinflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and Th cytokines (IFN-gamma, IL-4, IL-10 and IL-13) in patients with allergic asthma

21 January 2018

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CD4 T-lymphocyte activation in asthma is accompanied by increased serum concentrations of interleukin-5. Effect of glucocorticoid therapy

21 January 2018

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12 December 2020

Protein content in bronchoalveolar lavage fluid of patients with asthma and control subjects

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12 December 2020

Lung inflammation and epithelial changes in a murine model of atopic asthma

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12 December 2020

Production of serotonin by tryptophan hydroxylase 1 and release via platelets contribute to allergic airway inflammation

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12 December 2020

Role for IgE in airway secretions: IgE immune complexes are more potent inducers than antigen alone of airway inflammation in a murine model

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12 December 2020

Development of eosinophilic airway inflammation and airway hyperresponsiveness requires interleukin-5 but not immunoglobulin E or B lymphocytes

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12 December 2020

Interference of methysergide, a specific 5-hydroxytryptamine receptor antagonist, with airway chronic allergic inflammation and remodelling in a murine model of asthma

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12 December 2020

Modulation and induction of eosinophil chemotaxis by granulocyte-macrophage colony-stimulating factor and interleukin-3

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12 December 2020

A murine IL-4 receptor antagonist that inhibits IL-4- and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness

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12 December 2020

T(H)2-mediated pulmonary inflammation leads to the differential expression of ribonuclease genes by alveolar macrophages

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12 December 2020

Cytokine and eosinophil responses in the lung, peripheral blood, and bone marrow compartments in a murine model of allergen-induced airways inflammation

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25416380%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

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9 June 2020

1 reference