Intravenously injected human apolipoprotein A-I rapidly enters the central nervous system via the choroid plexus (Q35114943)

6 August 2017

Intravenously injected human apolipoprotein A-I rapidly enters the central nervous system via the choroid plexus (English)

1 reference

6 August 2017

Dhananjay Namjoshi

8

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Sophie Stukas

object named as

Sophie Stukas

1

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Jérôme Robert

object named as

Jerome Robert

Jayachandran N Kizhakkedathu

2

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15

object named as

Jayachandran N Kizhakkedathu

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ORCID Public Data File 2021

6 August 2017

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author name string

Michael Lee

3

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6 August 2017

Iva Kulic

4

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6 August 2017

Michael Carr

5

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6 August 2017

Katherine Tourigny

6

1 reference

6 August 2017

Jianjia Fan

7

1 reference

6 August 2017

Kalistyne Lemke

9

1 reference

6 August 2017

Nicole DeValle

10

1 reference

6 August 2017

Jeniffer Chan

11

1 reference

6 August 2017

Tammy Wilson

12

1 reference

6 August 2017

Anna Wilkinson

13

1 reference

6 August 2017

Rafi Chapanian

14

1 reference

6 August 2017

John R Cirrito

16

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6 August 2017

Michael N Oda

17

1 reference

6 August 2017

Cheryl L Wellington

18

1 reference

6 August 2017

12 November 2014

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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

6 August 2017

1 reference

6 August 2017

3

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6 August 2017

6

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6 August 2017

e001156

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Plasma proteins predict conversion to dementia from prodromal disease

6 August 2017

1 reference

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HDL-targeted therapies: progress, failures and future

9 July 2018

1 reference

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High-density lipoproteins and cerebrovascular integrity in Alzheimer's disease.

9 July 2018

1 reference

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Associations between serum cholesterol levels and cerebral amyloidosis

9 July 2018

1 reference

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A three-dimensional engineered artery model for in vitro atherosclerosis research

9 July 2018

1 reference

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Tanycyte-like cells form a blood-cerebrospinal fluid barrier in the circumventricular organs of the mouse brain

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338702

In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338702

Unraveling the complexities of the HDL lipidome

9 July 2018

1 reference

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Proteomic diversity of high density lipoproteins: our emerging understanding of its importance in lipid transport and beyond

9 July 2018

1 reference

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Physiology of blood-brain interfaces in relation to brain disposition of small compounds and macromolecules

9 July 2018

1 reference

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Novel biological functions of high-density lipoprotein cholesterol

9 July 2018

1 reference

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Epidemiology of Alzheimer disease

9 July 2018

1 reference

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Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

9 July 2018

1 reference

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Association of higher levels of high-density lipoprotein cholesterol in elderly individuals and lower risk of late-onset Alzheimer disease

9 July 2018

1 reference

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Overexpression of human apolipoprotein A-I preserves cognitive function and attenuates neuroinflammation and cerebral amyloid angiopathy in a mouse model of Alzheimer disease.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338702

Apolipoprotein A-I deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1DeltaE9 mice

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338702

Endothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin therapy

9 July 2018

1 reference

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Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer's disease

9 July 2018

1 reference

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Interrelationships among HDL metabolism, aging, and atherosclerosis

9 July 2018

1 reference

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Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function

9 July 2018

1 reference

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Human apolipoprotein A-I binds amyloid-beta and prevents Abeta-induced neurotoxicity

9 July 2018

1 reference

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Vascular risk factors, cognitive decline, and dementia

9 July 2018

1 reference

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Multiplicity of cerebrospinal fluid functions: New challenges in health and disease

9 July 2018

1 reference

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Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338702

The circumventricular organs: an atlas of comparative anatomy and vascularization.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338702

Megalin mediates the transport of leptin across the blood-CSF barrier.

9 July 2018

1 reference

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Apolipoprotein A-I coating of protamine-oligonucleotide nanoparticles increases particle uptake and transcytosis in an in vitro model of the blood-brain barrier

9 July 2018

1 reference

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Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects

9 July 2018

1 reference

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The role of the kidney in lipid metabolism

9 July 2018

1 reference

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Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338702

Uptake and transport of high-density lipoprotein (HDL) and HDL-associated alpha-tocopherol by an in vitro blood-brain barrier model

9 July 2018

1 reference

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Characterization of four lipoprotein classes in human cerebrospinal fluid

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338702

Decreased high-density lipoprotein cholesterol and serum apolipoprotein AI concentrations are highly correlated with the severity of Alzheimer's disease.

9 July 2018

1 reference

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Marked increases in concentrations of apolipoprotein in the cerebrospinal fluid of poliovirus-infected macaques: relations between apolipoprotein concentrations and severity of brain injury

9 July 2018

1 reference

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Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers

9 July 2018

1 reference

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Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

9 July 2018

1 reference

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Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new high density lipoprotein size subclasses

9 July 2018

1 reference

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Apolipoprotein C-III is an amyloid-β-binding protein and an early marker for Alzheimer's disease.

9 July 2018

1 reference

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Altered activation of endothelial anti- and proapoptotic pathways by high-density lipoprotein from patients with coronary artery disease: role of high-density lipoprotein-proteome remodeling

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338702

The LXR agonist GW3965 increases apoA-I protein levels in the central nervous system independent of ABCA1.

27 September 2018

1 reference

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Oxidative stress damage and oxidative stress responses in the choroid plexus in Alzheimer's disease.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338702

Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones.

27 September 2018

1 reference

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Abeta accumulation in choroid plexus is associated with mitochondrial-induced apoptosis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338702

The relation between apolipoprotein A-I and dementia: the Honolulu-Asia aging study

27 September 2018

1 reference

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ATP-Binding cassette transporter A1 modulates apolipoprotein A-I transcytosis through aortic endothelial cells.

27 September 2018

1 reference

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Overlapping expression patterns of the multiligand endocytic receptors cubilin and megalin in the CNS, sensory organs and developing epithelia of the rodent embryo.

27 September 2018

1 reference

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Scavenger receptor class B, type I mediates uptake of lipoprotein-associated phosphatidylcholine by primary porcine cerebrovascular endothelial cells.

27 September 2018

1 reference

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Proteomic studies of potential cerebrospinal fluid protein markers for Alzheimer's disease

27 September 2018

1 reference

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In VivoAssessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life

27 September 2018

1 reference

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Cerebrospinal fluid apo E and apo A-I concentrations in early- and late-onset Alzheimer's disease.

27 September 2018

1 reference

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Expression of apolipoprotein A-I in porcine brain endothelium in vitro.

27 September 2018

1 reference

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Low levels of serum apolipoprotein A I and A II in senile dementia.

27 September 2018

1 reference

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Binding, internalization and transport of apolipoprotein A-I by vascular endothelial cells

27 September 2018

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12 December 2020

Human serum albumin nanoparticles modified with apolipoprotein A-I cross the blood-brain barrier and enter the rodent brain

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12 December 2020

The β-chain of cell surface F(0)F(1) ATPase modulates apoA-I and HDL transcytosis through aortic endothelial cells

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12 December 2020

Choroid Plexus Megalin Is Involved in Neuroprotection by Serum Insulin-Like Growth Factor I

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12 December 2020

Marked decrease of plasma apolipoprotein AI and AII in Japanese patients with late-onset non-familial Alzheimer's disease

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12 December 2020

Brain expression of apolipoproteins E, J, and A-I in Alzheimer's disease

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12 December 2020

Effects of triamcinolone on brain and cerebrospinal fluid apolipoprotein E levels in rats

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12 December 2020

Identifiers

DOI

10.1161/JAHA.114.001156

1 reference

6 August 2017

1 reference

6 August 2017

1 reference