Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron (Q35111241)

6 August 2017

Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron (English)

1 reference

6 August 2017

0 references

0 references

0 references

0 references

Sally F Burn

3

0 references

Peter Hohenstein

object named as

Peter Hohenstein

14

0 references

Owen J Sansom

object named as

Owen J Sansom

11

0 references

author name string

Nils O Lindström

1

1 reference

6 August 2017

Melanie L Lawrence

2

1 reference

6 August 2017

Jeanette A Johansson

4

1 reference

6 August 2017

Elvira R M Bakker

5

1 reference

6 August 2017

Rachel A Ridgway

6

1 reference

6 August 2017

C-Hong Chang

7

1 reference

6 August 2017

Michele J Karolak

8

1 reference

6 August 2017

Leif Oxburgh

9

1 reference

6 August 2017

Denis J Headon

10

1 reference

6 August 2017

Ron Smits

12

1 reference

6 August 2017

Jamie A Davies

13

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 January 2014

1 reference

6 August 2017

1 reference

6 August 2017

3

1 reference

6 August 2017

e04000

1 reference

describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4337611/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Nephrons require Rho-kinase for proximal-distal polarity development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation

9 July 2018

1 reference

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A universal vector for high-efficiency multi-fragment recombineering of BACs and knock-in constructs

9 July 2018

1 reference

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Role for compartmentalization in nephron progenitor differentiation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development.

9 July 2018

1 reference

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Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks

9 July 2018

1 reference

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Wnt/β-catenin signaling and disease

9 July 2018

1 reference

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A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts

9 July 2018

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NOTCH1 functions as an oncogene by regulating the PTEN/PI3K/AKT pathway in clear cell renal cell carcinoma

9 July 2018

1 reference

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Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Notch signaling: simplicity in design, versatility in function

9 July 2018

1 reference

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Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells

9 July 2018

1 reference

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Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

BMP signaling in the nephron progenitor niche

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Calcium/NFAT signalling promotes early nephrogenesis

9 July 2018

1 reference

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Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

WT1 and kidney progenitor cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells.

9 July 2018

1 reference

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Emerging links between CDK cell cycle regulators and Wnt signaling

9 July 2018

1 reference

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Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo

9 July 2018

1 reference

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Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Phosphatidylinositol 3-kinase signaling does not activate the wnt cascade

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Regulation, necessity, and the misinterpretation of knockouts

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

An in vivo reporter of BMP signaling in organogenesis reveals targets in the developing kidney

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Organization of the pronephric kidney revealed by large-scale gene expression mapping.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Wt1 negatively regulates beta-catenin signaling during testis development

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Wnt/Notch signalling and information processing during development.

9 July 2018

1 reference

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Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Renal abnormalities and their developmental origin

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Myc deletion rescues Apc deficiency in the small intestine

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Glycogen synthase kinase-3 inactivation and stabilization of beta-catenin induce nephron differentiation in isolated mouse and rat kidney mesenchymes

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Wnt/beta-catenin signaling in cancer stemness and malignant behavior

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Exploring the specificity of the PI3K family inhibitor LY294002.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Faithful activation of an extra-bright red fluorescent protein in "knock-in" Cre-reporter mice ideally suited for lineage tracing studies.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Segmental expression of Notch and Hairy genes in nephrogenesis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Differential expression and function of cadherin-6 during renal epithelium development

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Direct and long-range action of a wingless morphogen gradient

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Control of calbindin-D28K expression in developing mouse kidney.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Threshold Methotrexate Concentration for In Vivo Inhibition of DNA Synthesis in Normal and Tumorous Target Tissues

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Canonical WNT/beta-catenin signaling is required for ureteric branching.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Tissue-specific expression of cre recombinase from the Pax8 locus

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Apoptosis in the cortex of the developing mouse kidney.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337611

Morphogenetic Interaction between Embryonic Mouse Tissues separated by a Membrane Filter

27 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.7554%2FELIFE.04000

A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentation

21 January 2018

1 reference

12 December 2020

Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex

1 reference

12 December 2020

β-Catenin signaling dosage dictates tissue-specific tumor predisposition in Apc-driven cancer

1 reference

12 December 2020

Induction of Early Stages of Kidney Tubule Differentiation by Lithium Ions

1 reference

12 December 2020

Genetic heterogeneity of Bartter's syndrome revealed by mutations in the K+ channel, ROMK

1 reference

12 December 2020

Identifiers

DOI

10.7554/ELIFE.04000

1 reference

6 August 2017

1 reference

6 August 2017

1 reference