Gpr48 deficiency induces polycystic kidney lesions and renal fibrosis in mice by activating Wnt signal pathway (Q35111058)

6 August 2017

Gpr48 deficiency induces polycystic kidney lesions and renal fibrosis in mice by activating Wnt signal pathway (English)

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6 August 2017

1 reference

Yongyan Dang

1

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6 August 2017

Bei Liu

2

1 reference

6 August 2017

Peng Xu

3

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6 August 2017

Pingya Zhu

4

1 reference

6 August 2017

Yimiao Zhai

5

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6 August 2017

Mingyao Liu

6

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6 August 2017

Xiyun Ye

7

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6 August 2017

language of work or name

English

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publication date

3 March 2014

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6 August 2017

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6 August 2017

9

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6 August 2017

3

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6 August 2017

e89835

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Creative Commons Attribution 4.0 International

6 August 2017

start time

3 March 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Expression of Wnt signaling components during Xenopus pronephros development

1 reference

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Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis

9 July 2018

1 reference

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Tissue-specific roles of Axin2 in the inhibition and activation of Wnt signaling in the mouse embryo

9 July 2018

1 reference

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Cystic kidney disease: the role of Wnt signaling

9 July 2018

1 reference

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Interplay of cadherin-mediated cell adhesion and canonical Wnt signaling

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Wnt/beta-catenin signaling promotes renal interstitial fibrosis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Wnt signaling in kidney development and disease.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Requirement of Wnt/beta-catenin signaling in pronephric kidney development

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development

9 July 2018

1 reference

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Canonical WNT signaling during kidney development

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Wnt signaling in polycystic kidney disease

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Roles of G-protein-coupled receptor signaling in cancer biology and gene transcription

9 July 2018

1 reference

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Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinoma cell invasiveness and metastasis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Defective postnatal development of the male reproductive tract in LGR4 knockout mice

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Mouse axin and axin2/conductin proteins are functionally equivalent in vivo

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

9 July 2018

1 reference

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TGF-beta signaling in renal disease

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Smad7 inhibits fibrotic effect of TGF-Beta on renal tubular epithelial cells by blocking Smad2 activation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

A role for Wnt-4 in renal fibrosis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

A possible role for metalloproteinases in renal cyst development

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3940658

Leucine-rich repeat-containing, G protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality

9 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0089835

GPR48 regulates epithelial cell proliferation and migration by activating EGFR during eyelid development

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0089835

Impaired hair placode formation with reduced expression of hair follicle-related genes in mice lacking Lgr4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0089835

Defective development of the gall bladder and cystic duct in Lgr4- hypomorphic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0089835

Intercellular Adhesion Molecule-1–Deficient Mice Are Resistant Against Renal Injury After Induction of Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0089835

Increased expression of MMP-2, MMP-9 (type IV collagenases/gelatinases), and MT1-MMP in canine X-linked Alport syndrome (XLAS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0089835

Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene

21 January 2018

1 reference

12 December 2020

Leucine-rich repeat-containing G protein-coupled receptor-4 (LGR4, Gpr48) is essential for renal development in mice

1 reference

12 December 2020

Protein kinase B/Akt-dependent phosphorylation of glycogen synthase kinase-3beta in irradiated vascular endothelium

1 reference

12 December 2020

Polycystic kidney disease

1 reference

12 December 2020

Extracellular signal-regulated kinase inhibition slows disease progression in mice with polycystic kidney disease

1 reference

12 December 2020

The proinflammatory role of hyaluronan-CD44 interactions in renal injury

1 reference

12 December 2020

Elevated TGFbeta-Smad signalling in experimental Pkd1 models and human patients with polycystic kidney disease

1 reference

12 December 2020

Progressive renal fibrosis in murine polycystic kidney disease: an immunohistochemical observation

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0089835

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DOI

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6 August 2017

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6 August 2017

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