Phosphodiesterase 3A (PDE3A) deletion suppresses proliferation of cultured murine vascular smooth muscle cells (VSMCs) via inhibition of mitogen-activated protein kinase (MAPK) signaling and alterations in critical cell cycle regulatory proteins (Q35110887)

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English	Phosphodiesterase 3A (PDE3A) deletion suppresses proliferation of cultured murine vascular smooth muscle cells (VSMCs) via inhibition of mitogen-activated protein kinase (MAPK) signaling and alterations in critical cell cycle regulatory proteins	scientific article

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Phosphodiesterase 3A (PDE3A) deletion suppresses proliferation of cultured murine vascular smooth muscle cells (VSMCs) via inhibition of mitogen-activated protein kinase (MAPK) signaling and alterations in critical cell cycle regulatory proteins (English)

1 reference

Europe PubMed Central

6 August 2017

author name string

Najma Begum

1

1 reference

Europe PubMed Central

6 August 2017

Steven Hockman

2

1 reference

Europe PubMed Central

6 August 2017

Vincent C Manganiello

3

1 reference

Europe PubMed Central

6 August 2017

language of work or name

0 references

publication date

1 June 2011

1 reference

Europe PubMed Central

6 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

6 August 2017

286

1 reference

Europe PubMed Central

6 August 2017

29

1 reference

Europe PubMed Central

6 August 2017

26238-26249

1 reference

Europe PubMed Central

6 August 2017

PKA and Epac synergistically inhibit smooth muscle cell proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Controlling the Mdm2-Mdmx-p53 Circuit

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9 July 2018

The regulation of p53 by phosphorylation: a model for how distinct signals integrate into the p53 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

9 July 2018

Role of PI3K/AKT, cPLA2 and ERK1/2 signaling pathways in insulin regulation of vascular smooth muscle cells proliferation.

1 reference

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9 July 2018

Role of smooth muscle cells in the initiation and early progression of atherosclerosis

1 reference

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9 July 2018

Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

9 July 2018

Phosphodiesterase regulation of nitric oxide signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling

1 reference

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Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart

1 reference

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Regulation of smooth muscle cells in development and vascular disease: current therapeutic strategies

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Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice

1 reference

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A scientific rationale for the CREST trial results: evidence for the mechanism of action of cilostazol in restenosis

1 reference

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MKP-1 expression and stabilization and cGK Ialpha prevent diabetes- associated abnormalities in VSMC migration.

1 reference

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9 July 2018

Cyclic nucleotide phosphodiesterase 3A-deficient mice as a model of female infertility

1 reference

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9 July 2018

Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

9 July 2018

New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

9 July 2018

Inflammation in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

9 July 2018

Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

9 July 2018

Immune mechanisms in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

9 July 2018

Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

9 July 2018

Regulation of the G2/M transition by p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

9 July 2018

Molecular pathways of cyclic nucleotide-induced inhibition of arterial smooth muscle cell proliferation

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Substitution of two insulin receptor carboxy-terminal tyrosines with phenylalanine impairs the expression of MAP kinase phosphatase-1 (MKP-1) mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

9 July 2018

Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Cross talk between NO and cyclic nucleotide phosphodiesterases in the modulation of signal transduction in blood vessel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Vascular smooth muscle cell growth and insulin regulation of mitogen-activated protein kinase in hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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The mitogenic effect of parathyroid hormone is associated with E2F-dependent activation of cyclin-dependent kinase 1 (cdc2) in osteoblast precursors

1 reference

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Conformation-dependent phosphorylation of p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1.

1 reference

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Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Inhibitors of cyclic nucleotide phosphodiesterase isozymes type-III and type-IV suppress mitogenesis of rat mesangial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Measurement of protein using bicinchoninic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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The pathogenesis of atherosclerosis--an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

9 July 2018

From growth to cell cycle control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Increased phosphodiesterase 3A/4B expression after angioplasty and the effect on VASP phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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1 reference

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cAMP phosphodiesterase inhibitors potentiate effects of prostacyclin analogs in hypoxic pulmonary vascular remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Differential regulation of mesangial cell mitogenesis by cAMP phosphodiesterase isozymes 3 and 4.

1 reference

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27 September 2018

Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

27 September 2018

Insulin inhibits PDGF-directed VSMC migration via NO/ cGMP increase of MKP-1 and its inactivation of MAPKs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

27 September 2018

Negative regulation of rho signaling by insulin and its impact on actin cytoskeleton organization in vascular smooth muscle cells: role of nitric oxide and cyclic guanosine monophosphate signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

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Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

27 September 2018

Suppression of arterial intimal hyperplasia by cilostamide, a cyclic nucleotide phosphodiesterase 3 inhibitor, in a rat balloon double-injury model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3138244

27 September 2018

Cyclic AMP Inhibits PDGF-stimulated Mitogen-activated Protein Kinase Activity in Rat Aortic Smooth Muscle Cells via Inactivation of c-Raf-1 Kinase and Induction of MAP Kinase Phosphatase-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.214155

21 January 2018

Restenosis after experimental angioplasty. Intimal, medial, and adventitial changes associated with constrictive remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/21632535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21632535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21632535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase is required for insulin-like growth factor-I-induced vascular smooth muscle cell proliferation and migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21632535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compartmentalization of cAMP signaling in mesangial cells by phosphodiesterase isozymes PDE3 and PDE4. Regulation of superoxidation and mitogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21632535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21632535

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.214155

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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