Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness (Q35093983)

6 August 2017

Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness (English)

1 reference

6 August 2017

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25609648%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Mark L. Siegal

series ordinal

3

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31 May 2020

author name string

Christopher R Bauer

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31 May 2020

publication date

21 January 2015

1 reference

Molecular Systems Biology

6 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25609648%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

11

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31 May 2020

issue

1

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31 May 2020

page(s)

773

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Histone variant HTZ1 shows extensive epistasis with, but does not increase robustness to, new mutations

31 May 2020

cites work

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9 July 2018

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Nodes having a major influence to break cooperation define a novel centrality measure: game centrality.

9 July 2018

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Single-cell phenomics reveals intra-species variation of phenotypic noise in yeast.

9 July 2018

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The details in the distributions: why and how to study phenotypic variability

9 July 2018

1 reference

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The many faces of pleiotropy

9 July 2018

1 reference

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Random phenotypic variation of yeast (Saccharomyces cerevisiae) single-gene knockouts fits a double pareto-lognormal distribution

9 July 2018

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Bet hedging in yeast by heterogeneous, age-correlated expression of a stress protectant

9 July 2018

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Nonheritable cellular variability accelerates the evolutionary processes of cancer

9 July 2018

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Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility

9 July 2018

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Varying virulence: epigenetic control of expression noise and disease processes

9 July 2018

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Stochastic receptor expression determines cell fate upon interferon treatment

9 July 2018

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A gene's ability to buffer variation is predicted by its fitness contribution and genetic interactions

9 July 2018

1 reference

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Coordinate control of gene expression noise and interchromosomal interactions in a MAP kinase pathway

9 July 2018

1 reference

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Functional roles for noise in genetic circuits

9 July 2018

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Robustness and evolvability in natural chemical resistance: identification of novel systems properties, biochemical mechanisms and regulatory interactions

9 July 2018

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A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

9 July 2018

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A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

9 July 2018

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Preview. A penetrating look at stochasticity in development

9 July 2018

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Variability in gene expression underlies incomplete penetrance

9 July 2018

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9 July 2018

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The genetic landscape of a cell

9 July 2018

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Evolution of colour vision in mammals

9 July 2018

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Robustness: mechanisms and consequences

9 July 2018

1 reference

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Partial penetrance facilitates developmental evolution in bacteria.

9 July 2018

1 reference

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Network hubs buffer environmental variation in Saccharomyces cerevisiae

9 July 2018

1 reference

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Frequency-modulated nuclear localization bursts coordinate gene regulation

9 July 2018

1 reference

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A comprehensive strategy enabling high-resolution functional analysis of the yeast genome.

9 July 2018

1 reference

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Nucleosome retention and the stochastic nature of promoter chromatin remodeling for transcription

9 July 2018

1 reference

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Interchromosomal interactions and olfactory receptor choice

9 July 2018

1 reference

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High-dimensional and large-scale phenotyping of yeast mutants.

9 July 2018

1 reference

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Bacterial persistence as a phenotypic switch

9 July 2018

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Exploration of essential gene functions via titratable promoter alleles

9 July 2018

1 reference

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Control of stochasticity in eukaryotic gene expression

9 July 2018

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Stochastic gene expression in fluctuating environments

9 July 2018

1 reference

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Under cover: causes, effects and implications of Hsp90-mediated genetic capacitance

9 July 2018

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Evolutionary capacitance as a general feature of complex gene networks

9 July 2018

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Waddington's canalization revisited: developmental stability and evolution

9 July 2018

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Hsp90 as a capacitor for morphological evolution

9 July 2018

1 reference

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Gene regulation during high-frequency switching in Candida albicans

9 July 2018

1 reference

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Budding yeast escape commitment to the phosphate starvation program using gene expression noise.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4332149

The robustness continuum.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4332149

Intrinsic variability of gene expression encoded in nucleosome positioning sequences.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4332149

Phenotypic diversity, population growth, and information in fluctuating environments.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4332149

Dissecting ensemble networks in ES cell populations reveals micro-heterogeneity underlying pluripotency

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4332149

Stochastic protein expression in individual cells at the single molecule level

16 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4332149

Dynamical effects of transcriptional pause-prone sites

16 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25609648

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.15252/MSB.20145264

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25609648%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25609648%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

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