Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity (Q35091388)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21670318%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

title

Loss of T cell CD98 H chain specifically ablates T cell clonal expansion and protects from autoimmunity (English)

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4 February 2020

3

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4 February 2020

author name string

Joseph Cantor

1

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4 February 2020

Marina Slepak

2

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4 February 2020

John T Chang

4

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4 February 2020

Mark H Ginsberg

5

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4 February 2020

language of work or name

English

0 references

publication date

13 June 2011

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4 February 2020

published in

Journal of Immunology

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4 February 2020

volume

187

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4 February 2020

page(s)

851-860

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4 February 2020

issue

2

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Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2)

4 February 2020

cites work

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Differentiation, expansion, and homeostasis of autoreactive T cells in type 1 diabetes mellitus

8 July 2018

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CD98hc facilitates B cell proliferation and adaptive humoral immunity

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse

8 July 2018

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CD98hc (SLC3A2) mediates integrin signaling.

8 July 2018

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Autoreactive T cells in human type 1 diabetes.

8 July 2018

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The TCR-HA, INS-HA transgenic model of autoimmune diabetes: limitations and expectations

8 July 2018

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Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells

8 July 2018

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Adhesion molecules as therapeutic targets for autoimmune diseases and transplant rejection

8 July 2018

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Lamprey lymphocyte-like cells express homologs of genes involved in immunologically relevant activities of mammalian lymphocytes

8 July 2018

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Distinct domains of CD98hc regulate integrins and amino acid transport

8 July 2018

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Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

8 July 2018

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Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance

8 July 2018

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Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation

8 July 2018

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

8 July 2018

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Complementation of dominant suppression implicates CD98 in integrin activation.

8 July 2018

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Constitutive class I-restricted exogenous presentation of self antigens in vivo

8 July 2018

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T cell receptor antagonist peptides induce positive selection

8 July 2018

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8 July 2018

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A review of T-cell receptors in multiple sclerosis: clonal expansion and persistence of human T-cells specific for an immunodominant myelin basic protein peptide

8 July 2018

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A predominant role of integrin alpha 4 in the spontaneous development of autoimmune diabetes in nonobese diabetic mice

8 July 2018

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The pathogenesis of adoptive murine autoimmune diabetes requires an interaction between alpha 4-integrins and vascular cell adhesion molecule-1.

8 July 2018

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8 July 2018

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Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus

8 July 2018

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8 July 2018

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8 July 2018

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A single naive CD8+ T cell precursor can develop into diverse effector and memory subsets.

27 September 2018

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27 September 2018

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Islet beta-cell-specific T cells can use different homing mechanisms to infiltrate and destroy pancreatic islets

27 September 2018

1 reference

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27 September 2018

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27 September 2018

1 reference

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The targeted disruption of the CD98 gene results in embryonic lethality.

27 September 2018

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Direct quantitation of rapid elimination of viral antigen-positive lymphocytes by antiviral CD8(+) T cells in vivo

27 September 2018

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Mucosal addressin is required for the development of diabetes in nonobese diabetic mice.

27 September 2018

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Cross-presentation of self antigens to CD8+ T cells: the balance between tolerance and autoimmunity

27 September 2018

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Following a diabetogenic T cell from genesis through pathogenesis

25 October 2018

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12 December 2020

The human 4F2 antigen: evidence for cryptic and noncryptic epitopes and for a role of 4F2 in human T lymphocyte activation

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12 December 2020

Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile

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12 December 2020

Monocyte-dependent regulation of T lymphocyte activation through CD98

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12 December 2020

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12 December 2020

Combined TLR/CD40 stimulation mediates potent cellular immunity by regulating dendritic cell expression of CD70 in vivo

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12 December 2020

On the pathogenicity of autoantigen-specific T-cell receptors

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12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1100002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21670318%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21670318%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference