Clinical results with AGI-1067: a novel antioxidant vascular protectant (Q35088538)

6 August 2017

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title

Clinical results with AGI-1067: a novel antioxidant vascular protectant (English)

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6 August 2017

1

Jean-Claude Tardif

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PubMed ID

12645643

6 August 2017

language of work or name

English

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publication date

1 February 2003

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American Journal of Cardiology

6 August 2017

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6 August 2017

91

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6 August 2017

3A

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6 August 2017

41A-49A

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Oxidative stress as a regulator of gene expression in the vasculature

6 August 2017

1 reference

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Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells

7 January 2021

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Atherosclerosis — An Inflammatory Disease

7 January 2021

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Transient release of lipid peroxides after coronary artery balloon angioplasty

7 January 2021

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Angioplasty increases coronary sinus F2-isoprostane formation: evidence for in vivo oxidative stress during PTCA

7 January 2021

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Increased NAD(P)H oxidase and reactive oxygen species in coronary arteries after balloon injury

7 January 2021

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Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins

7 January 2021

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Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity

7 January 2021

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Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability

7 January 2021

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Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat

7 January 2021

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Enzymatic and nonenzymatic cross-linking of collagen and elastin

7 January 2021

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Endothelial Dysfunction and Collagen Accumulation

7 January 2021

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Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent

7 January 2021

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Probucol inhibits neointimal thickening and macrophage accumulation after balloon injury in the cholesterol-fed rabbit

7 January 2021

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Probucol decreases neointimal formation in a swine model of coronary artery balloon injury. A possible role for antioxidants in restenosis

7 January 2021

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Antioxidant treatment inhibits the development of intimal thickening after balloon injury of the aorta in hypercholesterolemic rabbits

7 January 2021

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Combination of vitamins C and E alters the response to coronary balloon injury in the pig

7 January 2021

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Preventive effects of probucol on restenosis after percutaneous transluminal coronary angioplasty

7 January 2021

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Effectiveness of probucol in preventing restenosis after percutaneous transluminal coronary angioplasty

7 January 2021

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Effectiveness of an antioxidant in preventing restenosis after percutaneous transluminal coronary angioplasty: the Probucol Angioplasty Restenosis Trial

7 January 2021

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Probucol and multivitamins in the prevention of restenosis after coronary angioplasty. Multivitamins and Probucol Study Group

7 January 2021

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Prevention of restenosis after angioplasty in small coronary arteries with probucol

7 January 2021

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Effects of probucol on vascular remodeling after coronary angioplasty. Multivitamins and Protocol Study Group

7 January 2021

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Lovastatin plus probucol for prevention of restenosis after percutaneous transluminal coronary angioplasty

7 January 2021

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Antioxidants and prevention of restenosis after directional coronary atherectomy

7 January 2021

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Vessel size, antioxidants, and restenosis: never too small, not too little, but often too late

7 January 2021

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Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant

7 January 2021

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Supplementation with beta-carotene in vivo and in vitro does not inhibit low density lipoprotein oxidation.

7 January 2021

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Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits.

7 January 2021

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Arterial remodeling after coronary angioplasty: a serial intravascular ultrasound study

7 January 2021

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Studies on the mechanism of action of probucol

7 January 2021

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The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion

7 January 2021

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Effect of probucol on macrophages, leading to regression of xanthomas and atheromatous vascular lesions

7 January 2021

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Inhibition of hypercholesterolemia-induced atherosclerosis in the nonhuman primate by probucol. II. Cellular composition and proliferation.

7 January 2021

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Probucol enhances selective uptake of HDL-associated cholesteryl esters in vitro by a scavenger receptor B-I-dependent mechanism

7 January 2021

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Inhibition by probucol of interleukin 1 secretion and its implication in atherosclerosis

7 January 2021

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Probucol-associated tachyarrhythmic events and QT prolongation: importance of gender

7 January 2021

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Novel phenolic antioxidants as multifunctional inhibitors of inducible VCAM-1 expression for use in atherosclerosis

7 January 2021

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Probucol. A reappraisal of its pharmacological properties and therapeutic use in hypercholesterolaemia

7 January 2021

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The effect of probucol on femoral atherosclerosis: The Probucol Quantitative Regression Swedish Trial (PQRST)

7 January 2021

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Lowering of HDL 2b by Probucol Partly Explains the Failure of the Drug to Affect Femoral Atherosclerosis in Subjects With Hypercholesterolemia

7 January 2021

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Inhibition of hypercholesterolemia-induced atherosclerosis in the nonhuman primate by probucol. I. Is the extent of atherosclerosis related to resistance of LDL to oxidation?

7 January 2021

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Effects of probucol and pravastatin on common carotid atherosclerosis in patients with asymptomatic hypercholesterolemia. Fukuoka Atherosclerosis Trial (FAST).

7 January 2021

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Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse

7 January 2021

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Polymorphic ventricular tachycardia (Torsade de Pointes) associated with the use of probucol

7 January 2021

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Propranolol for probucol-induced QT prolongation with polymorphic ventricular tachycardia

7 January 2021

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Vitamins C and E inhibit O2- production in the pig coronary artery

7 January 2021

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A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization

7 January 2021

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Pathological analysis of local delivery of paclitaxel via a polymer-coated stent

7 January 2021

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Late coronary occlusion after intracoronary brachytherapy

7 January 2021

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Inhibitory effect of a single local probucol administration on neointimal formation in balloon-injured rat carotid artery

7 January 2021

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Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico

7 January 2021

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Vitamin E supplementation and cardiovascular events in high-risk patients

7 January 2021

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MRC/BHF Heart Protection Study of cholesterol-lowering therapy and of antioxidant vitamin supplementation in a wide range of patients at increased risk of coronary heart disease death: early safety and efficacy experience

7 January 2021

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Gamma-tocopherol detoxification of nitrogen dioxide: superiority to alpha-tocopherol

7 January 2021

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gamma-tocopherol traps mutagenic electrophiles such as NO(X) and complements alpha-tocopherol: physiological implications

7 January 2021

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Oral alpha-tocopherol supplements decrease plasma gamma-tocopherol levels in humans

7 January 2021

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Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease

7 January 2021

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Carvedilol for prevention of restenosis after directional coronary atherectomy : final results of the European carvedilol atherectomy restenosis (EUROCARE) trial.

7 January 2021

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Carvedilol, a novel multiple action antihypertensive agent with antioxidant activity and the potential for myocardial and vascular protection

7 January 2021

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Carvedilol, a new antihypertensive, prevents oxidation of human low density lipoprotein by macrophages and copper

7 January 2021

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Effect of probucol dosage on plasma lipid and lipoprotein levels and on protection of low density lipoprotein against in vitro oxidation in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903149-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Probucol-induced QT prolongation and torsades de pointes

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2802%2903149-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0002-9149(02)03149-1

1 reference

6 August 2017

1 reference

PubMed ID

12645643