Diverse roles of integrins in human T lymphocyte biology (Q35085517)

6 August 2017

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title

Diverse roles of integrins in human T lymphocyte biology (English)

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6 August 2017

Yuko J Miyamoto

1

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6 August 2017

Bernard F Andruss

2

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6 August 2017

Jason S Mitchell

3

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6 August 2017

Matthew J Billard

4

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6 August 2017

Bradley W McIntyre

5

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6 August 2017

1 January 2003

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6 August 2017

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6 August 2017

27

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6 August 2017

1

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6 August 2017

71-84

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https://scigraph.springernature.com/pub.10.1385/ir:27:1:71

6 August 2017

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cites work

Signaling through focal adhesion kinase

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12 December 2020

Integrin alpha 4 beta 7 co-stimulation of human peripheral blood T cell proliferation.

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12 December 2020

Regulated expression of focal adhesion kinase-related nonkinase, the autonomously expressed C-terminal domain of focal adhesion kinase

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12 December 2020

Polyunsaturated fatty acids inhibit T cell signal transduction by modification of detergent-insoluble membrane domains

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12 December 2020

Integrin-associated protein (CD47) is a comitogenic molecule on CD3-activated human T cells

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12 December 2020

Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor

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12 December 2020

Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex

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12 December 2020

Costimulatory regulation of T cell function.

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12 December 2020

The effect of TGF-beta1 on immune responses of naïve versus memory CD4+ Th1/Th2 T cells

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12 December 2020

Membrane raft microdomains mediate front-rear polarity in migrating cells

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12 December 2020

Killer-cell inhibitory receptors, CD158a/b, are upregulated by interleukin-2, but not interferon-gamma or interleukin-4.

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12 December 2020

The inhibition of vascular smooth muscle cell migration by peptide and antibody antagonists of the alphavbeta3 integrin complex is reversed by activated calcium/calmodulin- dependent protein kinase II.

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12 December 2020

Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity

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12 December 2020

Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity

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12 December 2020

CD28 ligation in T-cell activation: evidence for two signal transduction pathways

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12 December 2020

Modulation of the affinity of integrin alpha IIb beta 3 (GPIIb-IIIa) by the cytoplasmic domain of alpha IIb

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12 December 2020

Cytotoxic T-lymphocyte interaction with fibronectin and vitronectin: activated adhesion and cosignalling

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12 December 2020

Complementation of dominant suppression implicates CD98 in integrin activation.

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12 December 2020

Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn

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12 December 2020

Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin

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12 December 2020

The immunological synapse: a molecular machine controlling T cell activation

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12 December 2020

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

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12 December 2020

Interleukin 9 induces expression of three cytokine signal inhibitors: cytokine-inducible SH2-containing protein, suppressor of cytokine signalling (SOCS)-2 and SOCS-3, but only SOCS-3 overexpression suppresses interleukin 9 signalling

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12 December 2020

The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells.

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12 December 2020

Nuclear transcription factors that bind to elements of the IL-2 promoter. Induction requirements in primary human T cells

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12 December 2020

VLA-4 mediates CD3-dependent CD4+ T cell activation via the CS1 alternatively spliced domain of fibronectin

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12 December 2020

Integrins: emerging paradigms of signal transduction

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12 December 2020

Costimulation of T-cell growth

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12 December 2020

Surface antigen CD98(4F2): not a single membrane protein, but a family of proteins with multiple functions

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12 December 2020

The conserved membrane-proximal region of an integrin cytoplasmic domain specifies ligand binding affinity.

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12 December 2020

Regulated expression and binding of three VLA (beta 1) integrin receptors on T cells

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12 December 2020

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

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12 December 2020

Lymphocyte function-associated antigen 1 dominates very late antigen 4 in binding of activated T cells to endothelium

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12 December 2020

Anergy and exhaustion are independent mechanisms of peripheral T cell tolerance

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12 December 2020

A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

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12 December 2020

Beta2-integrin, LFA-1, and TCR/CD3 synergistically induce tyrosine phosphorylation of focal adhesion kinase (pp125(FAK)) in PHA-activated T cells

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12 December 2020

High affinity very late antigen-4 subsets expressed on T cells are mandatory for spontaneous adhesion strengthening but not for rolling on VCAM-1 in shear flow

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12 December 2020

Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1.

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12 December 2020

Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

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12 December 2020

A fundamental difference in the capacity to induce proliferation of naive T cells between CD28 and other co-stimulatory molecules

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12 December 2020

Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains

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12 December 2020

Suppressor effects and cyclic AMP accumulation by the CD29 molecule of CD4+ lymphocytes

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12 December 2020

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

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12 December 2020

The tetraspanin superfamily: molecular facilitators

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12 December 2020

Avidity regulation of integrins: the driving force in leukocyte adhesion

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12 December 2020

Vascular cell adhesion molecule 1 induces T-cell antigen receptor-dependent activation of CD4+T lymphocytes

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12 December 2020

Alpha 4 beta 1 (CD49d/CD29) integrin costimulation of human T cells enhances transcription factor and cytokine induction in the absence of altered sensitivity to anti-CD3 stimulation

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12 December 2020

Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells

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12 December 2020

Focal adhesions - the cytoskeletal connection

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12 December 2020

Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

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12 December 2020

Specific inhibition of T lymphocyte coactivation by triggering integrin beta 1 reveals convergence of beta 1, beta 2, and beta 7 signaling pathways

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12 December 2020

Negative regulation of T cell activation.

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12 December 2020

T cell adhesion to intercellular adhesion molecule-1 (ICAM-1) is controlled by cell spreading and the activation of integrin LFA-1

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12 December 2020

Integrin cross talk: activation of lymphocyte function-associated antigen-1 on human T cells alters alpha4beta1- and alpha5beta1-mediated function.

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12 December 2020

Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3

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12 December 2020

Subsecond induction of alpha4 integrin clustering by immobilized chemokines stimulates leukocyte tethering and rolling on endothelial vascular cell adhesion molecule 1 under flow conditions

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12 December 2020

Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation

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12 December 2020

Tyrosine phosphorylation of Crk-associated substrate lymphocyte-type is a critical element in TCR- and beta 1 integrin-induced T lymphocyte migration

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12 December 2020

Regulation of beta 1 integrin-mediated adhesion by T cell receptor signaling involves ZAP-70 but differs from signaling events that regulate transcriptional activity

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12 December 2020

Cooperative signaling by alpha 5 beta 1 and alpha 4 beta 1 integrins regulates metalloproteinase gene expression in fibroblasts adhering to fibronectin

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12 December 2020

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

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12 December 2020

Convergence between CD98 and integrin-mediated T-lymphocyte co-stimulation

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12 December 2020

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

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12 December 2020

GPI-microdomains: a role in signalling via immunoreceptors.

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12 December 2020

The actin cytoskeleton regulates LFA-1 ligand binding through avidity rather than affinity changes

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12 December 2020

Inhibition of CD28/CD3-mediated costimulation of naive and memory human T lymphocytes by intracellular incorporation of polyclonal antibodies specific for the activator protein-1 transcriptional complex.

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12 December 2020

Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy

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12 December 2020

Trans-dominant inhibition of integrin function.

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12 December 2020

Paxillin binding is not the sole determinant of focal adhesion localization or dominant-negative activity of focal adhesion kinase/focal adhesion kinase-related nonkinase

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12 December 2020

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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12 December 2020

Regulation of the avidity of integrin alpha 4 beta 7 by the beta 7 cytoplasmic domain.

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12 December 2020

Complexity and specificity of integrin signalling.

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12 December 2020

ICAM-1 and B7-1 provide similar but distinct costimulation for CD8+ T cells, while CD4+ T cells are poorly costimulated by ICAM-1.

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12 December 2020

Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation

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12 December 2020

Membrane compartmentation is required for efficient T cell activation.

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12 December 2020

T cell activation determined by T cell receptor number and tunable thresholds.

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12 December 2020

Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates

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12 December 2020

Costimulation with integrin ligands intercellular adhesion molecule-1 or vascular cell adhesion molecule-1 augments activation-induced death of antigen-specific CD4+ T lymphocytes.

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12 December 2020

Tensegrity: the architectural basis of cellular mechanotransduction

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12 December 2020

Modulation of TCR signaling by beta1 integrins: role of the tyrosine phosphatase SHP-1.

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12 December 2020

Fibronectin binding promotes a PKC-dependent modulation of NF-kappa B in human T cells

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12 December 2020

Evidence for the involvement of three distinct signals in the induction of IL-2 gene expression in human T lymphocytes.

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12 December 2020

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

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12 December 2020

Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins.

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12 December 2020

Suppressive effect of T cell proliferation via the CD29 molecule. The CD29 mAb 1 "K20" decreases diacylglycerol and phosphatidic acid levels in activated T cells

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12 December 2020

Differential expression of VLA-alpha 4 and VLA-beta 1 discriminates multiple subsets of CD4+CD45R0+ "memory" T cells

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12 December 2020

Regulation of T cell proliferation by anti-CD49d and anti-CD29 monoclonal antibodies

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12 December 2020

Integrins: versatility, modulation, and signaling in cell adhesion

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12 December 2020

Fibronectin promotes proliferation of naive and memory T cells by signaling through both the VLA-4 and VLA-5 integrin molecules

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12 December 2020

The alphavbeta3 integrin regulates alpha5beta1-mediated cell migration toward fibronectin

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12 December 2020

Intracellular analysis of interleukin-2 induction provides direct evidence at the single cell level of differential coactivation requirements for CD45RA+ and CD45RO+ T cell subsets

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12 December 2020

Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling

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12 December 2020

Integrin leukocyte function-associated antigen-1-mediated cell binding can be activated by clustering of membrane rafts

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12 December 2020

Roles of adhesion molecules in T-cell recognition: fundamental similarities between four integrins on resting human T cells (LFA-1, VLA-4, VLA-5, VLA-6) in expression, binding, and costimulation

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12 December 2020

Large, detergent-resistant complexes containing murine antigens Thy-1 and Ly-6 and protein tyrosine kinase p56lck.

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12 December 2020

Costimulation of proliferative responses of resting CD4+ T cells by the interaction of VLA-4 and VLA-5 with fibronectin or VLA-6 with laminin

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12 December 2020

MAb 18D3 Triggering of Integrin β1 Will Prevent but Not Terminate Proliferation of Human T Cells

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12 December 2020

CD81 expressed on human thymocytes mediates integrin activation and interleukin 2-dependent proliferation

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12 December 2020

Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins

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12 December 2020

Functional consequences of costimulation by ICAM-1 on IL-2 gene expression and T cell activation

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12 December 2020

Activation of human CD4 T lymphocytes. Interaction of fibronectin with VLA-5 receptor on CD4 cells induces the AP-1 transcription factor

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12 December 2020

A role for CD98 in cellular activation.

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12 December 2020

Inhibition of IL-4 responses after T cell priming in the context of LFA-1 costimulation is not reversed by restimulation in the presence of CD28 costimulation

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12 December 2020

Signaling by vascular cell adhesion molecule-1 (VCAM-1) through VLA-4 promotes CD3-dependent T cell proliferation

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12 December 2020

Mutational evidence for control of cell adhesion through integrin diffusion/clustering, independent of ligand binding

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12 December 2020

Identifiers

DOI

10.1385/IR:27:1:71

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Dimensions Publication ID

6 August 2017

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