Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer's disease. (Q35080456)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23919677%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer's disease (English)

1 reference

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6 March 2020

0 references

2

1 reference

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6 March 2020

Cara L Croft

4

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6 March 2020

Claire Garwood

5

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6 March 2020

Selina Wray

7

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6 March 2020

Diane P. Hanger

9

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6 March 2020

Wendy Noble

10

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6 March 2020

author name string

Joe Atherton

1

1 reference

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6 March 2020

Marie Bondulich

3

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6 March 2020

Resham Chhabra

6

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6 March 2020

Andreas Jeromin

8

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6 March 2020

publication date

18 September 2013

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6 March 2020

1 reference

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6 March 2020

volume

13

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6 March 2020

issue

1

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6 March 2020

page(s)

49-59

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Physiological release of endogenous tau is stimulated by neuronal activity.

6 March 2020

cites work

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8 July 2018

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8 July 2018

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Na+ -Ca2+ exchanger (NCX3) knock-out mice display an impairment in hippocampal long-term potentiation and spatial learning and memory

8 July 2018

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8 July 2018

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8 July 2018

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Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation

8 July 2018

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Calpain activation and Na+/Ca2+ exchanger degradation occur downstream of calcium deregulation in hippocampal neurons exposed to excitotoxic glutamate

8 July 2018

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Calcium-activated calpain-2 is a mediator of beta cell dysfunction and apoptosis in type 2 diabetes

8 July 2018

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Dysregulation of calcium homeostasis in Alzheimer's disease

8 July 2018

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Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression

8 July 2018

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Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease

8 July 2018

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A novel calcium-binding protein is associated with tau proteins in tauopathy

8 July 2018

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Na+/Ca2+ exchangers: three mammalian gene families control Ca2+ transport.

8 July 2018

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The plasma membrane Na+/Ca2+ exchanger is cleaved by distinct protease families in neuronal cell death

8 July 2018

1 reference

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YM-244769, a novel Na+/Ca2+ exchange inhibitor that preferentially inhibits NCX3, efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage

8 July 2018

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Cellular and subcellular localization of Na+-Ca2+ exchanger protein isoforms, NCX1, NCX2, and NCX3 in cerebral cortex and hippocampus of adult rat

8 July 2018

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Calcium dysregulation in Alzheimer's disease: recent advances gained from genetically modified animals

8 July 2018

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Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease.

8 July 2018

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8 July 2018

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The calpains in aging and aging-related diseases

8 July 2018

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8 July 2018

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Calpain activity regulates the cell surface distribution of amyloid precursor protein. Inhibition of calpains enhances endosomal generation of beta-cleaved C-terminal APP fragments

8 July 2018

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Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Caspase-3 cleaved spectrin colocalizes with neurofilament-immunoreactive neurons in Alzheimer's disease.

8 July 2018

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Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity

21 January 2018

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N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.

21 January 2018

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Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

21 January 2018

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Abeta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks

21 January 2018

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Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease.

21 January 2018

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m-Calpain-mediated cleavage of Na+/Ca2+ exchanger-1 in caveolae vesicles isolated from pulmonary artery smooth muscle.

21 January 2018

1 reference

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High levels of synaptosomal Na(+)-Ca(2+) exchangers (NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affected by Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12148

Sodium/calcium exchanger subtypes NCX1, NCX2 and NCX3 show cell-specific expression in rat hippocampus cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FACEL.12148

Calpastatin levels affect calpain activation and calpain proteolytic activity in APP transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

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Unexpected abundance of pathological tau in progressive supranuclear palsy white matter.

21 January 2018

1 reference

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Mechanisms of cell death in neurodegenerative disorders.

21 January 2018

1 reference

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Loss of the presynaptic vesicle protein synaptophysin in hippocampus correlates with cognitive decline in Alzheimer disease.

27 September 2018

1 reference

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Antisense oligonucleotide suppression of Na(+)/Ca(2+) exchanger activity in primary neurons from rat brain

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23919677

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23919677

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/ACEL.12148

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23919677%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23919677%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

23919677

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23919677%20AND%20SRC:MED&resulttype=core&format=json