BAG-1: a multifunctional regulator of cell growth and survival (Q35078440)

6 August 2017

BAG-1: a multifunctional regulator of cell growth and survival (English)

1 reference

6 August 2017

1 reference

Graham Packham

5

1 reference

ORCID Public Data File 2021

author name string

Paul A Townsend

1

1 reference

6 August 2017

Ramsey I Cutress

2

1 reference

6 August 2017

Adam Sharp

3

1 reference

6 August 2017

Matthew Brimmell

4

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 March 2003

1 reference

Biochimica et Biophysica Acta

6 August 2017

1 reference

6 August 2017

1603

1 reference

6 August 2017

2

1 reference

6 August 2017

83-98

1 reference

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

A protein that interacts with members of the nuclear hormone receptor family: identification and cDNA cloning

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Cloning of cDNAs encoding the human BAG1 protein and localization of the human BAG1 gene to chromosome 9p12

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Mammalian cells express two differently localized Bag-1 isoforms generated by alternative translation initiation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Human BAG-1/RAP46 protein is generated as four isoforms by alternative translation initiation and overexpressed in cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

High level expression of differentially localized BAG-1 isoforms in some oestrogen receptor-positive human breast cancers.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Overexpression of anti-apoptotic gene BAG-1 in human cervical cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Control of translation initiation in animals.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

The p36 isoform of BAG-1 is translated by internal ribosome entry following heat shock

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

1 reference

7 January 2021

Mechanisms underlying ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1 promotes apoptosis induced by N-(4-hydroxyphenyl)retinamide in human cervical carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Structure-function analysis of Bag1 proteins. Effects on androgen receptor transcriptional activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

A nuclear action of the eukaryotic cochaperone RAP46 in downregulation of glucocorticoid receptor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Hsp70-RAP46 interaction in downregulation of DNA binding by glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Loss of bag-1 immunoreactivity in rat brain after transient middle cerebral artery occlusion

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Growth hormone prevents apoptosis through activation of nuclear factor-kappaB in interleukin-3-dependent Ba/F3 cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

IFN-gamma upregulates anti-apoptotic gene expression and inhibits apoptosis in IL-3-dependent hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Cloning and characterization of the human BAG-1 gene promoter: upregulation by tumor-derived p53 mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Deregulated Bag-1 protein expression in human oral squamous cell carcinomas and lymph node metastases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1 accelerates cell motility of human gastric cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

The hsp70-associating protein Hap46 binds to DNA and stimulates transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Bcl-2 gene family and related proteins in mammary gland involution and breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1 is a novel cytoplasmic binding partner of the membrane form of heparin-binding EGF-like growth factor: a unique role for proHB-EGF in cell survival regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1 expression and function in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1, an anti-apoptotic tumour marker

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1: a novel biomarker predicting long-term survival in early-stage breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Hsp70 chaperone machines.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Prediction of novel Bag-1 homologs based on structure/function analysis identifies Snl1p as an Hsp70 co-chaperone in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Mammalian protein RAP46: an interaction partner and modulator of 70 kDa heat shock proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Human DnaJ homologs dj2 and dj3, and bag-1 are positive cochaperones of hsc70

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Proteins interacting with the molecular chaperone hsp70/hsc70: physical associations and effects on refolding activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Distinct isoforms of the cofactor BAG-1 differentially affect Hsc70 chaperone function.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Bag-1M accelerates nucleotide release for human Hsc70 and Hsp70 and can act concentration-dependent as positive and negative cofactor.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

GrpE-like regulation of the hsc70 chaperone by the anti-apoptotic protein BAG-1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1, a negative regulator of Hsp70 chaperone activity, uncouples nucleotide hydrolysis from substrate release.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Characterization of interactions between the anti-apoptotic protein BAG-1 and Hsc70 molecular chaperones

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Dissection of the ATP-binding domain of the chaperone hsc70 for interaction with the cofactor Hap46.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Interference between proteins Hap46 and Hop/p60, which bind to different domains of the molecular chaperone hsp70/hsc70.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Cofactor-induced modulation of the functional specificity of the molecular chaperone Hsc70

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Modulation of in vivo HSP70 chaperone activity by Hip and Bag-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Bag1 functions in vivo as a negative regulator of Hsp70 chaperone activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Differential effects of the hsp70-binding protein BAG-1 on glucocorticoid receptor folding by the hsp90-based chaperone machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

hsp70 interacting protein Hip does not affect glucocorticoid receptor folding by the hsp90-based chaperone machinery except to oppose the effect of BAG-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Molecular chaperone targeting and regulation by BAG family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Tumor necrosis factor receptor 1 is an ATPase regulated by silencer of death domain

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Prevention of constitutive TNF receptor 1 signaling by silencer of death domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Isolation of Bcl-2 binding proteins that exhibit homology with BAG-1 and suppressor of death domains protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG4/SODD protein contains a short BAG domain

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1 family of cochaperones in the modulation of nuclear receptor action.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1L protein enhances androgen receptor function

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG1L enhances trans-activation function of the vitamin D receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1 p50 isoform interacts with the vitamin D receptor and its cellular overexpression inhibits the vitamin D pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

RAP46 is a negative regulator of glucocorticoid receptor action and hormone-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1, a novel Bcl-2-interacting protein, activates expression of human JC virus

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1M, an isoform of Bcl-2-interacting protein BAG-1, enhances gene expression driven by CMV promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Bc1-2, Raf-1 and mitochondrial regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Bag1-Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Bag-1 up-regulation in anti-CD4 mAb treated allo-activated T cells confers resistance to apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Anti-cell death activity promotes pulmonary metastasis of melanoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Bag-1 and Bcl-2 gene transfer in malignant glioma: modulation of cell cycle regulation and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Prolonged cell survival enhances peritoneal dissemination of gastric cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Ubiquitin-dependent degradation of certain protein substrates in vitro requires the molecular chaperone Hsc70

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

From the cradle to the grave: molecular chaperones that may choose between folding and degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Protein turnover: a CHIP programmed for proteolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

HSP90 as a new therapeutic target for cancer therapy: the story unfolds

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Role of the heat shock response and molecular chaperones in oncogenesis and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

BAG-1 inhibits p53-induced but not apoptin-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Fibroblast growth factor-2 stimulates endothelial nitric oxide synthase expression and inhibits apoptosis by a nitric oxide-dependent pathway in Nb2 lymphoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

Regulation of programmed cell death following T cell activation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2803%2900002-7

7 January 2021

10.1016/S0304-419X(03)00002-7

Identifiers

DOI

1 reference

6 August 2017

1 reference