Biological effects and use of PrPSc- and PrP-specific antibodies generated by immunization with purified full-length native mouse prions (Q35076872)

6 August 2017

title

Biological effects and use of PrPSc- and PrP-specific antibodies generated by immunization with purified full-length native mouse prions (English)

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6 August 2017

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James W Ironside

8

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author name string

Benjamin Petsch

1

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6 August 2017

Andreas Müller-Schiffmann

2

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6 August 2017

Anna Lehle

3

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6 August 2017

Elizabeta Zirdum

4

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6 August 2017

Ingrid Prikulis

5

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6 August 2017

Franziska Kuhn

6

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6 August 2017

Alex J Raeber

7

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6 August 2017

Carsten Korth

9

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6 August 2017

Lothar Stitz

10

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6 August 2017

language of work or name

English

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publication date

23 February 2011

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6 August 2017

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6 August 2017

volume

85

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6 August 2017

issue

9

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6 August 2017

page(s)

4538-4546

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Protein aggregation diseases: pathogenicity and therapeutic perspectives

6 August 2017

cites work

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Continuous quinacrine treatment results in the formation of drug-resistant prions

8 July 2018

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The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes

8 July 2018

1 reference

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Complementarity determining regions of an anti-prion protein scFv fragment orchestrate conformation specificity and antiprion activity

8 July 2018

1 reference

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Formation of native prions from minimal components in vitro

8 July 2018

1 reference

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Search for a prion-specific nucleic acid

8 July 2018

1 reference

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Strain-specified characteristics of mouse synthetic prions

8 July 2018

1 reference

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Synthetic mammalian prions

8 July 2018

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Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrPSc

8 July 2018

1 reference

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PrPSc binding antibodies are potent inhibitors of prion replication in cell lines.

8 July 2018

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8 July 2018

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Generation of antibodies against prion protein in wild-type mice via helix 1 peptide immunization

8 July 2018

1 reference

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Generation of antibodies against prion protein by scrapie-infected cell immunization of PrP(0/0) mice

8 July 2018

1 reference

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A prion protein epitope selective for the pathologically misfolded conformation

8 July 2018

1 reference

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Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

8 July 2018

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Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody

8 July 2018

1 reference

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Efficient lymphoreticular prion propagation requires PrP(c) in stromal and hematopoietic cells.

8 July 2018

1 reference

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Cultured cell sublines highly susceptible to prion infection

8 July 2018

1 reference

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Generation of monoclonal antibodies against prion proteins with an unconventional nucleic acid-based immunization strategy.

8 July 2018

1 reference

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Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication

8 July 2018

1 reference

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Eight prion strains have PrP(Sc) molecules with different conformations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Monoclonal antibody F89/160.1.5 defines a conserved epitope on the ruminant prion protein.

8 July 2018

1 reference

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Prion (PrPSc)-specific epitope defined by a monoclonal antibody

8 July 2018

1 reference

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Neutralizing antiviral B cell responses

8 July 2018

1 reference

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Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.

8 July 2018

1 reference

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T helper cell-independent neutralizing B cell response against vesicular stomatitis virus: role of antigen patterns in B cell induction?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Novel proteinaceous infectious particles cause scrapie

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

A cellular gene encodes scrapie PrP 27-30 protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Purification and properties of the cellular prion protein from Syrian hamster brain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Continuous cultures of fused cells secreting antibody of predefined specificity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Non-infectious aggregates of the prion protein react with several PrPSc-directed antibodies.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Toward molecular dissection of PrPC-PrPSc interactions

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Detection of prion epitopes on PrP and PrP of transmissible spongiform encephalopathies using specific monoclonal antibodies to PrP.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Identification of a protein that purifies with the scrapie prion.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

A protease-resistant protein is a structural component of the scrapie prion.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3126253

Induction of antibodies against human prion proteins (PrP) by DNA-mediated immunization of PrP0/0 mice

27 September 2018

1 reference

12 December 2020

Synthetic peptide vaccines yield monoclonal antibodies to cellular and pathological prion proteins of ruminants

1 reference

12 December 2020

Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay

1 reference

12 December 2020

Monoclonal antibodies inhibit prion replication and delay the development of prion disease

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.02467-10

1 reference

6 August 2017

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6 August 2017

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