Chronic neurodegeneration after traumatic brain injury: Alzheimer disease, chronic traumatic encephalopathy, or persistent neuroinflammation? (Q35064981)

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English	Chronic neurodegeneration after traumatic brain injury: Alzheimer disease, chronic traumatic encephalopathy, or persistent neuroinflammation?	scientific article

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scholarly article

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23 February 2020

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Chronic neurodegeneration after traumatic brain injury: Alzheimer disease, chronic traumatic encephalopathy, or persistent neuroinflammation? (English)

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Europe PubMed Central

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23 February 2020

traumatic brain injury

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Alzheimer's disease

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chronic traumatic encephalopathy

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2

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23 February 2020

author name string

Alan I Faden

1

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publication date

1 January 2015

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23 February 2020

Neurotherapeutics

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23 February 2020

12

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23 February 2020

1

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23 February 2020

143-150

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23 February 2020

https://scigraph.springernature.com/pub.10.1007/s13311-014-0319-5

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Traumatic brain injury and risk of dementia in older veterans

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Prospectively assessed clinical outcomes in concussive blast vs nonblast traumatic brain injury among evacuated US military personnel

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Proinflammatory milieu in combat-related PTSD is independent of depression and early life stress

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Exploratory associations with tumor necrosis factor-α, disinhibition and suicidal endorsement after traumatic brain injury.

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8 July 2018

Repeated mild traumatic brain injury causes chronic neuroinflammation, changes in hippocampal synaptic plasticity, and associated cognitive deficits

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8 July 2018

Is there evidence for neurodegenerative change following traumatic brain injury in children and youth? A scoping review

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8 July 2018

Functional status after blast-plus-impact complex concussive traumatic brain injury in evacuated United States military personnel

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8 July 2018

Progressive neurodegeneration after experimental brain trauma: association with chronic microglial activation.

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8 July 2018

Chronic neuropathological and neurobehavioral changes in a repetitive mild traumatic brain injury model

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8 July 2018

Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury

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8 July 2018

Reversal of established traumatic brain injury-induced, anxiety-like behavior in rats after delayed, post-injury neuroimmune suppression

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8 July 2018

Blocking neurogenic inflammation for the treatment of acute disorders of the central nervous system.

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8 July 2018

Increased risk of dementia in patients with mild traumatic brain injury: a nationwide cohort study

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8 July 2018

Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies

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8 July 2018

Mild traumatic brain injury: longitudinal regional brain volume changes.

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8 July 2018

The role of markers of inflammation in traumatic brain injury.

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8 July 2018

Chronic neuropathologies of single and repetitive TBI: substrates of dementia?

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8 July 2018

Inflammation and white matter degeneration persist for years after a single traumatic brain injury

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8 July 2018

Late exercise reduces neuroinflammation and cognitive dysfunction after traumatic brain injury.

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8 July 2018

Long-term upregulation of inflammation and suppression of cell proliferation in the brain of adult rats exposed to traumatic brain injury using the controlled cortical impact model

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8 July 2018

The spectrum of disease in chronic traumatic encephalopathy

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8 July 2018

Activation of mGluR5 and inhibition of NADPH oxidase improves functional recovery after traumatic brain injury

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8 July 2018

Risk for late-life re-injury, dementia and death among individuals with traumatic brain injury: a population-based study

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8 July 2018

Longitudinal volumetric changes following traumatic brain injury: a tensor-based morphometry study

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8 July 2018

Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention

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8 July 2018

Traumatic brain injury, microglia, and Beta amyloid

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8 July 2018

Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury

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8 July 2018

Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation

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8 July 2018

Frontal cortex neuropathology in dementia pugilistica

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8 July 2018

Widespread τ and amyloid-β pathology many years after a single traumatic brain injury in humans.

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8 July 2018

Repetitive closed-skull traumatic brain injury in mice causes persistent multifocal axonal injury and microglial reactivity

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8 July 2018

Emerging histomorphologic phenotypes of chronic traumatic encephalopathy in American athletes.

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8 July 2018

Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

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8 July 2018

Microglia in neurodegenerative disease

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8 July 2018

Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?

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8 July 2018

Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments

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8 July 2018

Neuroinflammation – An Early Event in Both the History and Pathogenesis of Alzheimer’s Disease

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8 July 2018

Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury

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8 July 2018

Heterogeneity of microglial activation in the innate immune response in the brain

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8 July 2018

Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury

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8 July 2018

Activation of metabotropic glutamate receptor 5 modulates microglial reactivity and neurotoxicity by inhibiting NADPH oxidase

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8 July 2018

Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury.

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8 July 2018

Serial changes in the white matter diffusion tensor imaging metrics in moderate traumatic brain injury and correlation with neuro-cognitive function

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8 July 2018

Metabotropic glutamate receptor 5 activation inhibits microglial associated inflammation and neurotoxicity

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8 July 2018

Long-term global and regional brain volume changes following severe traumatic brain injury: a longitudinal study with clinical correlates

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8 July 2018

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

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8 July 2018

Longitudinal changes in patients with traumatic brain injury assessed with diffusion-tensor and volumetric imaging

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8 July 2018

A lack of amyloid beta plaques despite persistent accumulation of amyloid beta in axons of long-term survivors of traumatic brain injury

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8 July 2018

Prolonged microgliosis in the rhesus monkey central nervous system after traumatic brain injury

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8 July 2018

Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans

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8 July 2018

Longitudinal changes in global brain volume between 79 and 409 days after traumatic brain injury: relationship with duration of coma.

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8 July 2018

A specific amyloid-beta protein assembly in the brain impairs memory

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8 July 2018

Chronic traumatic encephalopathy in a National Football League player

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8 July 2018

Long-term accumulation of amyloid-beta, beta-secretase, presenilin-1, and caspase-3 in damaged axons following brain trauma

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8 July 2018

Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication.

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8 July 2018

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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8 July 2018

Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease.

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8 July 2018

Progressive atrophy and neuron death for one year following brain trauma in the rat.

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8 July 2018

A beta 42 is the predominant form of amyloid beta-protein in the brains of short-term survivors of head injury.

1 reference

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8 July 2018

Head injury and the risk of Alzheimer's disease: a case control study.

1 reference

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8 July 2018

Beta amyloid protein deposition in the brain after severe head injury: implications for the pathogenesis of Alzheimer's disease

1 reference

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8 July 2018

The aftermath of boxing

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8 July 2018

Head injury as a risk factor for Alzheimer's disease.

1 reference

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8 July 2018

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

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8 July 2018

The association between head trauma and Alzheimer's disease

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8 July 2018

The occult aftermath of boxing

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8 July 2018

βA4 amyloid protein deposition in brain after head trauma

1 reference

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8 July 2018

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

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8 July 2018

Chronic Inflammation After Severe Traumatic Brain Injury: Characterization and Associations With Outcome at 6 and 12 Months Postinjury.

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27 September 2018

Relationship of collegiate football experience and concussion with hippocampal volume and cognitive outcomes.

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27 September 2018

Traumatic brain injury and young onset dementia: a nationwide cohort study.

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27 September 2018

Serum brain biomarker level, neurocognitive performance, and self-reported symptom changes in soldiers repeatedly exposed to low-level blast: a breacher pilot study

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27 September 2018

The neuroinflammatory response in humans after traumatic brain injury.

1 reference

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27 September 2018

Population based study on patients with traumatic brain injury suggests increased risk of dementia

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27 September 2018

Spreading of neurodegenerative pathology via neuron-to-neuron transmission of β-amyloid.

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27 September 2018

Microglial activation and traumatic brain injury.

1 reference

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27 September 2018

Inflammation after trauma: microglial activation and traumatic brain injury.

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27 September 2018

Magnetic resonance imaging evidence of progression of subacute brain atrophy in moderate to severe traumatic brain injury.

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27 September 2018

Association of increased cortical soluble abeta42 levels with diffuse plaques after severe brain injury in humans.

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27 September 2018

Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury.

1 reference

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27 September 2018

Amyloid β accumulation in axons after traumatic brain injury in humans

1 reference

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27 September 2018

Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes.

1 reference

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27 September 2018

beta-amyloid (Abeta)42(43), abeta42, abeta40 and apoE immunostaining of plaques in fatal head injury.

1 reference

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27 September 2018

Long-term intracerebral inflammatory response after experimental focal brain injury in rat.

1 reference

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27 September 2018

Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig.

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27 September 2018

One-year study of spatial memory performance, brain morphology, and cholinergic markers after moderate controlled cortical impact in rats.

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27 September 2018

Enduring cognitive, neurobehavioral and histopathological changes persist for up to one year following severe experimental brain injury in rats.

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27 September 2018

Risk factors for late-onset Alzheimer's disease: a population-based, case-control study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322076

27 September 2018

Early detection of axonal injury after human head trauma using immunocytochemistry for beta-amyloid precursor protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322076

27 September 2018

Diffusion tensor imaging during recovery from severe traumatic brain injury and relation to clinical outcome: a longitudinal study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4322076

16 November 2018

Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25421001

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of microglial activation after human traumatic brain injury are revealed by delayed expression of macrophage-related proteins MRP8 and MRP14

1 reference

https://pubmed.ncbi.nlm.nih.gov/25421001

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Documented head injury in early adulthood and risk of Alzheimer's disease and other dementias

1 reference

https://pubmed.ncbi.nlm.nih.gov/25421001

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Head trauma as a risk factor for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/25421001

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paraneoplastic neurological syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25421001

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term intracerebral inflammatory response after traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25421001

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged activation of NF-kappaB following traumatic brain injury in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25421001

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S13311-014-0319-5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25421001%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25421001%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25421001%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

ResearchGate publication ID

0 references

Sitelinks

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