Use of the A(2A) adenosine receptor as a physiological immunosuppressor and to engineer inflammation in vivo (Q35059150)

6 August 2017

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title

Use of the A(2A) adenosine receptor as a physiological immunosuppressor and to engineer inflammation in vivo (English)

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6 August 2017

Michail V Sitkovsky

1

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PubMed ID

12566076

6 August 2017

language of work or name

English

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publication date

1 February 2003

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6 August 2017

Biochemical Pharmacology

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6 August 2017

65

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6 August 2017

493-501

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6 August 2017

4

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Prospects for organ and tissue replacement

6 August 2017

1 reference

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Tissue engineering--current challenges and expanding opportunities

7 January 2021

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Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model.

7 January 2021

1 reference

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Heat shock proteins, inflammation, and cardiovascular disease

7 January 2021

1 reference

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Role of inflammatory mediators in thrombogenesis

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Inflammation in acute coronary syndromes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Lipid mediator class switching during acute inflammation: signals in resolution.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

7 January 2021

1 reference

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Human A(2A) adenosine receptors: high-affinity agonist binding to receptor-G protein complexes containing Gbeta(4).

7 January 2021

1 reference

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Synthesis, biological activity, and molecular modeling investigation of new pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as human A(3) adenosine receptor antagonists

7 January 2021

1 reference

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Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides

7 January 2021

1 reference

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Cyclic AMP-dependent inhibition of human neutrophil oxidative activity by substituted 2-propynylcyclohexyl adenosine A(2A) receptor agonists

7 January 2021

1 reference

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Adenosine analogue reduces spinal cord reperfusion injury in a time-dependent fashion

7 January 2021

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CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy

7 January 2021

1 reference

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Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance released by non-adrenergic inhibitory nerves in the gut.

7 January 2021

1 reference

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Stimulated formation of adenosine 3',5'-cyclic phosphate in cerebral cortex: synergism between electrical activity and biogenic amines

7 January 2021

1 reference

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Metabolism of [14C]adenine and derivatives by cerebral tissues, superfused and electrically stimulated

7 January 2021

1 reference

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Regulation of Coronary Blood Flow1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Release of adenosine and lack of release of ATP from contracting skeletal muscle

7 January 2021

1 reference

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Adenosine release from stimulated mast cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Extracellular ATP in T-lymphocyte activation: possible role in effector functions

7 January 2021

1 reference

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Molecular approach to adenosine receptors: receptor-mediated mechanisms of tissue protection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Hypoxia-induced inhibition of adenosine kinase potentiates cardiac adenosine release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Adenosine, an endogenous anti-inflammatory agent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Propentofylline inhibits polymorphonuclear leukocyte recruitment in vivo by a mechanism involving adenosine A2A receptors

7 January 2021

1 reference

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Inhibition by Adenosine and by 2-Chloroadenosine of the Formation and Embolization of Platelet Thrombi

7 January 2021

1 reference

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Histamine release in vitro: inhibition by catecholamines and methylxanthines

7 January 2021

1 reference

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Adenosine Inhibition of Lymphocyte-Mediated Cytolysis: Possible Role of Cyclic Adenosine Monophosphate

7 January 2021

1 reference

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Origin of adenosine released from rat vas deferens by nerve stimulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Selective amplification and cloning of four new members of the G protein-coupled receptor family

7 January 2021

1 reference

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Adenosine receptor subtypes: characterization and therapeutic regulation

7 January 2021

1 reference

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A2B adenosine and P2Y2 receptors stimulate mitogen-activated protein kinase in human embryonic kidney-293 cells. cross-talk between cyclic AMP and protein kinase c pathways

7 January 2021

1 reference

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Down-regulation of P2U-purinergic nucleotide receptor messenger RNA expression during in vitro differentiation of human myeloid leukocytes by phorbol esters or inflammatory activators.

7 January 2021

1 reference

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Transient up-regulation of P2Y2 nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes

7 January 2021

1 reference

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Inflammatory cytokines regulate function and expression of adenosine A(2A) receptors in human monocytic THP-1 cells.

7 January 2021

1 reference

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Adenosine as a possible inhibitor of killer T-cell activation in the microenvironment of solid tumours

7 January 2021

1 reference

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Endogenous adenosine curtails lipopolysaccharide-stimulated tumour necrosis factor synthesis

7 January 2021

1 reference

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Memory of extracellular adenosine A2A purinergic receptor-mediated signaling in murine T cells

7 January 2021

1 reference

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Cloned adenosine A3 receptors: pharmacological properties, species differences and receptor functions

7 January 2021

1 reference

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An agonist of adenosine A3 receptors decreases interleukin-12 and interferon-gamma production and prevents lethality in endotoxemic mice

7 January 2021

1 reference

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Activation of adenosine A3 receptors on macrophages inhibits tumor necrosis factor-alpha

7 January 2021

1 reference

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Ligand-activation of the adenosine A2a receptors inhibits IL-12 production by human monocytes.

7 January 2021

1 reference

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Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor

7 January 2021

1 reference

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A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice

7 January 2021

1 reference

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Disruption of the A(3) adenosine receptor gene in mice and its effect on stimulated inflammatory cells

7 January 2021

1 reference

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Cyclic nucleotide phosphodiesterase (PDE) inhibitors and immunomodulation

7 January 2021

1 reference

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Molecular mechanisms for protein kinase A-mediated modulation of immune function

7 January 2021

1 reference

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G proteins: transducers of receptor-generated signals

7 January 2021

1 reference

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Purinergic signalling: pathophysiological roles

7 January 2021

1 reference

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Prostaglandins as modulators of immunity

7 January 2021

1 reference

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Exocytosis of cytolytic granules may not be required for target cell lysis by cytotoxic T-lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Antigen-receptor interaction requirement for conjugate formation and lethal-hit triggering by cytotoxic T lymphocytes can be bypassed by protein kinase C activators and Ca2+ ionophores

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Differential expression of calmodulin-binding proteins in B, T lymphocytes and thymocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Extracellular ATP as a possible mediator of cell-mediated cytotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Purine-mediated signalling in pain and visceral perception

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Structure and function of adenosine receptors and their genes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Study of A(2A) adenosine receptor gene deficient mice reveals that adenosine analogue CGS 21680 possesses no A(2A) receptor-unrelated lymphotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Adenosine-mediated cardioprotection in ischemic-reperfused mouse heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Selective adenosine-A2A activation reduces lung reperfusion injury following transplantation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

Selective A(2A) adenosine receptor activation reduces skin pressure ulcer formation and inflammation

7 January 2021

1 reference

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Autacoids as modulators of the inflammatory and immune response

7 January 2021

1 reference

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Design, synthesis, and evaluation of novel A2A adenosine receptor agonists

7 January 2021

1 reference

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A(2A) adenosine receptor-mediated inhibition of renal injury and neutrophil adhesion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901548-4

The adenosine/neutrophil paradox resolved: human neutrophils possess both A1 and A2 receptors that promote chemotaxis and inhibit O2 generation, respectively

7 January 2021

1 reference

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Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation

7 January 2021

1 reference

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Turnover of adenosine in plasma of human and dog blood

7 January 2021

1 reference

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Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: synergy with the type IV phosphodiesterase inhibitor, rolipram

7 January 2021

1 reference

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Adenosine contributes to neutrophil-mediated loss of myocardial function in post-ischemic guinea-pig hearts

7 January 2021

1 reference

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HIF-1: mediator of physiological and pathophysiological responses to hypoxia

7 January 2021

1 reference

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Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1 alpha in activated T lymphocytes

7 January 2021

1 reference

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10.1016/S0006-2952(02)01548-4

7 January 2021

Identifiers

DOI

1 reference

release_bdrxpq6gmrdslljxbbbqpynzra

6 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bdrxpq6gmrdslljxbbbqpynzra

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

12566076

1 reference

PubMed ID

12566076