Treatment and sampling protocols for transgenic mutation assays (Q35054605)

6 August 2017

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title

Treatment and sampling protocols for transgenic mutation assays (English)

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6 August 2017

John A Heddle

1

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PubMed ID

12552586

6 August 2017

Hans-Joerg Martus

series ordinal

2

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PubMed ID

12552586

6 August 2017

George R Douglas

series ordinal

3

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6 August 2017

1 January 2003

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Environmental and Molecular Mutagenesis

6 August 2017

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6 August 2017

41

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6 August 2017

1

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6 August 2017

1-6

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ENU-induced mutagenesis at a single A: T base pair in transgenic mice containing phi X174.

6 August 2017

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Response of the phiX174 am3, cs70 transgene to acute and chronic ENU exposure: implications for protocol design

21 January 2018

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Mutation induction by N-propyl-N-nitrosourea in eight MutaMouse organs.

21 January 2018

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Extent of CpG methylation is not proportional to the in vivo spontaneous mutation frequency at transgenic loci in Big Blue rodents

21 January 2018

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Methylation of CpG dinucleotides in the lacI gene of the Big Blue transgenic mouse

21 January 2018

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Differential mutation of transgenic and endogenous loci in vivo

21 January 2018

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Mutagenicity of 4-nitroquinoline 1-oxide in the MutaMouse

21 January 2018

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Somatic mutation in the mammary gland: influence of time and estrus

21 January 2018

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Proliferation is necessary for both repair and mutation in transgenic mouse cells

21 January 2018

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7 January 2021

Treatment of lacZ plasmid-based transgenic mice with benzo[a]pyrene: measurement of DNA adduct levels, mutant frequencies, and mutant spectra

1 reference

7 January 2021

Mutation selection and the natural history of cancer

1 reference

7 January 2021

A test for neutrality of mutations of the lacZ transgene

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7 January 2021

Effects of extended chronic exposures on endogenous and transgenic loci: implications for low-dose extrapolations

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7 January 2021

Temporal and molecular characteristics of lacZ mutations in somatic tissues of transgenic mice

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7 January 2021

Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo

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7 January 2021

Treatment protocols for transgenic mutation assays in vivo

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7 January 2021

Why do stem cells exist?

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7 January 2021

In vivo transgenic mutation assays

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7 January 2021

Distribution of spontaneous CpG-associated G:C --> A:T mutations in the lacZ gene of Muta mice: effects of CpG methylation, the sequence context of CpG sites, and severity of mutations on the activity of the lacZ gene product

1 reference

7 January 2021

Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage lambda transgene target

1 reference

7 January 2021

Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice

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7 January 2021

Transgenic models for detection of mutations in tumors and normal tissues of rodents

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7 January 2021

Enhanced somatic mutation rates induced in stem cells of mice by low chronic exposure to ethylnitrosourea

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7 January 2021

Relative sensitivity of the endogenous hprt gene and lacI transgene in ENU-treated Big Blue B6C3F1 mice.

1 reference

7 January 2021

Further characterization and validation of gpt delta transgenic mice for quantifying somatic mutations in vivo.

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7 January 2021

Comparison of somatic mutation in a transgenic versus host locus

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7 January 2021

The accumulation and persistence of somatic mutations in vivo

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7 January 2021

Identifiers

DOI

10.1002/EM.10131

1 reference

6 August 2017

1 reference

PubMed ID

12552586