Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review). (Q35054306)

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English	Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review).	scientific article

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scholarly article

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17 December 2019

Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review) (English)

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Europe PubMed Central

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17 December 2019

Gabriella Leonarduzzi

1

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17 December 2019

author name string

Barbara Sottero

2

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17 December 2019

Giuseppe Poli

3

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17 December 2019

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1 December 2002

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17 December 2019

Journal of Nutritional Biochemistry

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17 December 2019

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17 December 2019

700-710

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17 December 2019

12

1 reference

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17 December 2019

Dietary cholesterol and atherosclerosis

1 reference

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7 January 2021

based on heuristic

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Coronary heart disease: dietary links and pathogenesis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of endothelial denudation and cholesterol feeding on in vivo transport of albumin, glucose, and water across rabbit carotid artery

1 reference

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7 January 2021

based on heuristic

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Functional alteration of endothelium by short-term cholesterol feeding

1 reference

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7 January 2021

based on heuristic

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Diet, plasma cholesterol and coronary heart disease

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The pathogenesis of atherosclerosis--an update

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Angiotoxicity and atherogenicity of cholesterol oxides

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Oxysterols, cholesterol biosynthesis, and vascular endothelial cell monolayer barrier function

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Up-regulation of the fibrogenic cytokine TGF-beta1 by oxysterols: a mechanistic link between cholesterol and atherosclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

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Angiotoxicity of oxygenated sterols and possible precursors

1 reference

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7 January 2021

based on heuristic

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Cholesterol oxidation derivatives and arterial endothelial damage

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Biological activities of oxysterols

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxysterols: biological activities and physicochemical studies

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Review of progress in sterol oxidations: 1987-1995.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Biological effects of oxysterols: current status

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxysterols and atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxysterol biosynthetic enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxysterols: modulators of cholesterol metabolism and other processes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Removal of cholesterol from extrahepatic sources by oxidative mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

7-Ketocholesterol

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cholesterol homeostasis: a role for oxysterols.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a potent oxysterol regulator of lipid metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of the lipophilic factor produced by macrophages that stimulates steroidogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Plasma lipid transfer proteins, high-density lipoproteins, and reverse cholesterol transport

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Cholesterol feeding increases plasma and aortic tissue cholesterol oxide levels in parallel: further evidence for the role of cholesterol oxidation in atherosclerosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Capillary GC quantification of cholesterol oxidation products in plasma lipoproteins of fasted humans

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of cholesterol oxidation products formed by oxidative modification of low density lipoprotein

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Lipids and oxidised lipids in human atherosclerotic lesions at different stages of development

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Lipids and oxidised lipids in human atheroma and normal aorta

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Isolation and quantification of cholesterol oxides in dairy products by selected ion monitoring mass spectrometry.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Cholesterol oxides in processed meats

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Occurrence of lipid oxidation products in foods

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Sterol Oxides in Foodstuffs: A Review

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of acyl-coenzyme A:cholesterol acyltransferase by cholesterol or by oxysterol in a cell-free system

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Cholesterol autoxidation 1981-1986.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Quantification of Cholesterol Oxidation Products in a Variety of Foods

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Absorption of Cholesterol Oxidation Products from Ordinary Foodstuff in Humans

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Intestinal absorption and fecal excretion of 5,6 alpha-epoxy-5 alpha-cholesta-3 beta-ol by the male Wistar rat

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Lymphatic absorption of oxidized cholesterol in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Absorption of dietary cholesterol oxidation products and incorporation into rat lymph chylomicrons

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The effect of oxidizing cholesterol on gastrointestinal absorption, plasma clearance, tissue distribution, and processing by endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Relative contributions of parenchymal and non-parenchymal (sinusoidal) liver cells in the uptake of chylomicron remnants

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Kinetics of biliary secretion of chylomicron remnant cholesterol (esters) in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Probucol reduces plasma and aortic wall oxysterol levels in cholesterol fed rabbits independently of its plasma cholesterol lowering effect

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Antioxidant treatment inhibits the development of intimal thickening after balloon injury of the aorta in hypercholesterolemic rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo oxidised cholesterol in atherosclerosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Plasma levels of lipid and cholesterol oxidation products and cytokines in diabetes mellitus and cigarette smoking: effects of vitamin E treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Bile acid biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Demonstration of 26-hydroxylation of C27-steroids in human skin fibroblasts, and a deficiency of this activity in cerebrotendinous xanthomatosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Formation of 7 alpha- and 7 beta-hydroxylated bile acid precursors from 27-hydroxycholesterol in human liver microsomes and mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Cholesterol 7 alpha-hydroxylase is up-regulated by the competitive inhibitor 7-oxocholesterol in rat liver.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Metabolism of an oxysterol, 7-ketocholesterol, by sterol 27-hydroxylase in HepG2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

7-Ketocholesterol delivered to mice in chylomicron remnant-like particles is rapidly metabolised, excreted and does not accumulate in aorta

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Apolipoprotein A-I-mediated efflux of sterols from oxidized LDL-loaded macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidized monocyte-derived macrophages in aortic atherosclerotic lesion from apolipoprotein E-deficient mice and from human carotid artery contain lipid peroxides and oxysterols

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Macrophage uptake of oxidized LDL inhibits lysosomal sphingomyelinase, thus causing the accumulation of unesterified cholesterol-sphingomyelin-rich particles in the lysosomes. A possible role for 7-Ketocholesterol

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Down-regulation of hormone-sensitive lipase in sterol ester-laden J774.2 macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Lysosomal destabilization during macrophage damage induced by cholesterol oxidation products

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Pathogenesis of liver fibrosis: role of oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

4-Hydroxynonenal in the pathomechanisms of oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Reactivity of taurine with aldehydes and its physiological role

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Serum 4-hydroxy-2-nonenal-modified albumin is elevated in patients with type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Serum level of 7 alpha-hydroxycholesterol in hypercholesterolemic patients treated with cholestyramine.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of a more electronegatively charged LDL subfraction by ion exchange HPLC

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of the activity of the low density lipoprotein receptor in human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of apoB-100 secondary structure and conformation in hydroperoxide rich, electronegative LDL(-).

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Oleate potentiates oxysterol inhibition of transcription from sterol regulatory element-1-regulated promoters and maturation of sterol regulatory element-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxysterol-induced apoptosis in human monocytic cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxysterols induced apoptosis in cultured smooth muscle cells through CPP32 protease activation and bcl-2 protein downregulation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7beta-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Different patterns of IL-1beta secretion, adhesion molecule expression and apoptosis induction in human endothelial cells treated with 7alpha-, 7beta-hydroxycholesterol, or 7-ketocholesterol

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxysterol-induced cell death in U937 and HepG2 cells at reduced and normal serum concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of apoptosis and of interleukin-1beta secretion by 7beta-hydroxycholesterol and 7-ketocholesterol: partial inhibition by Bcl-2 overexpression.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Glutathione is implied in the control of 7-ketocholesterol-induced apoptosis, which is associated with radical oxygen species production

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

7beta-hydroxycholesterol induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas/Fas ligand-mediated death pathway is involved in oxLDL-induced apoptosis in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of oxysterol-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The pathogenesis of atherosclerosis: a perspective for the 1990s

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidized LDL induces monocytic cell expression of interleukin-8, a chemokine with T-lymphocyte chemotactic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Human monocytes/macrophages release TNF-alpha in response to Ox-LDL

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

The expression of the adhesion molecules ICAM-1, VCAM-1, PECAM, and E-selectin in human atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Macrophages isolated from human atherosclerotic plaques produce IL-8, and oxysterols may have a regulatory function for IL-8 production

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxysterol activators of liver X receptor and 9-cis-retinoic acid promote sequential steps in the synthesis and secretion of tumor necrosis factor-alpha from human monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

Lipoprotein trafficking in vascular cells. Molecular Trojan horses and cellular saboteurs

1 reference

https://api.crossref.org/works/10.1016%2FS0955-2863%2802%2900222-X

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1016/S0955-2863(02)00222-X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12550054%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12550054%20AND%20SRC:MED&resulttype=core&format=json

17 December 2019

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