Selective retinoids and rexinoids in cancer therapy and chemoprevention (Q35053227)

6 August 2017

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title

Selective retinoids and rexinoids in cancer therapy and chemoprevention (English)

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6 August 2017

F Christopher Zusi

1

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PubMed ID

12547017

6 August 2017

Matthew V Lorenzi

series ordinal

2

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PubMed ID

12547017

6 August 2017

Valerie Vivat-Hannah

series ordinal

3

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6 August 2017

1 December 2002

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6 August 2017

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6 August 2017

7

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6 August 2017

23

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6 August 2017

1165-1174

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Retinoic acid biosynthesis and metabolism

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Metabolic conversion of retinol to retinoic acid mediates the biological responsiveness of human mammary epithelial cells to retinol

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Embryonic retinoic acid synthesis is essential for early mouse post-implantation development

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Selective ablation of retinoid X receptor alpha in hepatocytes impairs their lifespan and regenerative capacity

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Vitamin A, differentiation and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Transcriptional repression by nuclear hormone receptors

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Co-regulator recruitment and the mechanism of retinoic acid receptor synergy

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

The promise of retinoids to fight against cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Mediator complexes and transcription.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

RAR-independent RXR signaling induces t(15;17) leukemia cell maturation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Analysis of homo- and heterodimerization of retinoid receptors in solution

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Ligand- and DNA-induced dissociation of RXR tetramers 1 1Edited by M. Yaniv

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Selective agonists of retinoic acid receptors: comparative toxicokinetics and embryonic exposure.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

A new class of RAR subtype selective retinoids: correlation of pharmacological effects with receptor activity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Retinoid-induced hypertriglyceridemia in rats is mediated by retinoic acid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Retinoids and their receptors in cancer development and chemoprevention

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Methylation and silencing of the retinoic acid receptor-beta2 gene in breast cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

The targeted disruption of both alleles of RARbeta(2) in F9 cells results in the loss of retinoic acid-associated growth arrest.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Evidence that retinoic acid receptor beta induction by retinoids is important for tumor cell growth inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Tumor-suppressive effect of the retinoic acid receptor beta in human epidermoid lung cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Discovery and design of retinoic acid receptor and retinoid X receptor class- and subtype-selective synthetic analogs of all-trans-retinoic acid and 9-cis-retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Novel synthetic retinoids and separation of the pleiotropic retinoidal activities

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Recent developments in receptor-selective retinoids

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Structural basis for isotype selectivity of the human retinoic acid nuclear receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Serine 232 and methionine 272 define the ligand binding pocket in retinoic acid receptor subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

The N-terminal portion of domain E of retinoic acid receptors alpha and beta is essential for the recognition of retinoic acid and various analogs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Syntheses and structure-activity relationships of 5,6,7, 8-tetrahydro-5,5,8,8-tetramethyl-2-quinoxaline derivatives with retinoic acid receptor alpha agonistic activity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Identification of a retinoic acid receptor alpha subtype specific agonist

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Retinobenzoic acids. 1. Structure-activity relationships of aromatic amides with retinoidal activity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor gamma

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Identification of retinoic acid receptor beta subtype specific agonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Identification of highly potent retinoic acid receptor alpha-selective antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Identification of a novel class of retinoic acid receptor beta-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Activation of specific RXR heterodimers by an antagonist of RXR homodimers

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Novel retinoid X receptor antagonists: specific inhibition of retinoid synergism in RXR-RAR heterodimer actions

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Successful treatment of relapse of acute promyelocytic leukemia with a new synthetic retinoid, Am80

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Relapsed acute promyelocytic leukemia previously treated with all-trans retinoic acid: clinical experience with a new synthetic retinoid, Am-80.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Bioactivities of N-(4-hydroxyphenyl) retinamide and retinoyl beta-glucuronide.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Effect of the retinoid X receptor-selective ligand LGD1069 on mammary carcinoma after tamoxifen failure

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Bexarotene is effective and safe for treatment of refractory advanced-stage cutaneous T-cell lymphoma: multinational phase II-III trial results

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

Initial clinical trial of a selective retinoid X receptor ligand, LGD1069

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902526-6

7 January 2021

10.1016/S1359-6446(02)02526-6

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12547017