High-throughput methods for the development of new catalytic asymmetric reactions (Q35053178)

6 August 2017

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title

High-throughput methods for the development of new catalytic asymmetric reactions (English)

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6 August 2017

John F Traverse

1

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PubMed ID

12546918

6 August 2017

Marc L Snapper

series ordinal

2

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6 August 2017

1 October 2002

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6 August 2017

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6 August 2017

7

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6 August 2017

1002-1012

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6 August 2017

19

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Target-oriented and diversity-oriented organic synthesis in drug discovery

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New methods for the high-throughput screening of enantioselective catalysts and biocatalysts

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Emerging methods for the rapid determination of enantiomeric excess

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Discovery of exceptionally efficient catalysts for solvent-free enantioselective hetero-Diels-Alder reaction.

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Discovery of a catalytic asymmetric phosphorylation through selection of a minimal kinase mimic: a concise total synthesis of D-myo-inositol-1-phosphate

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Schiff Base Catalysts for the Asymmetric Strecker Reaction Identified and Optimized from Parallel Synthetic Libraries

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Combinatorial Chemistry for Ligand Development in Catalysis: Synthesis and Catalysis Screening of Peptidosulfonamide Tweezers on the Solid Phase

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Three-component catalytic asymmetric synthesis of aliphatic amines

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Aluminum-catalyzed asymmetric addition of TMSCN to aromatic and aliphatic ketones promoted by an easily accessible and recyclable peptide ligand

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Modular Pyridinyl Peptide Ligands in Asymmetric Catalysis: Enantioselective Synthesis of Quaternary Carbon Atoms Through Copper-Catalyzed Allylic Substitutions

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Modular peptide-based phosphine ligands in asymmetric catalysis: efficient and enantioselective Cu-catalyzed conjugate additions to five-, six-, and seven-membered cyclic enones.

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Cu-catalyzed asymmetric conjugate additions of alkylzinc reagents to acyclic aliphatic enones

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Tuning the activity of an enzyme for unusual environments: sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide

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Directed evolution of an enantioselective lipase

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Fluorogenic polypropionate fragments for detecting stereoselective aldolases

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EMDee: an enzymatic method for determining enantiomeric excess

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In situ enzymatic screening (ISES): a tool for catalyst discovery and reaction development

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Reaction microarrays: a method for rapidly determining the enantiomeric excess of thousands of samples.

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Amino acids and peptides as asymmetric organocatalysts

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A Chemosensor-Based Approach to Catalyst Discovery in Solution and on Solid Support

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Selection of enantioselective acyl transfer catalysts from a pooled peptide library through a fluorescence-based activity assay: an approach to kinetic resolution of secondary alcohols of broad structural scope

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Fluorescence-based screening of asymmetric acylation catalysts through parallel enantiomer analysis. Identification of a catalyst for tertiary alcohol resolution

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Screening of homogeneous catalysts by fluorescence resonance energy transfer. Identification of catalysts for room-temperature Heck reactions.

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Thermographic selection of effective catalysts from an encoded polymer-bound library

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IR-Thermographic Screening of Thermoneutral or Endothermic Transformations: The Ring-Closing Olefin Metathesis Reaction

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Complex synthetic chemical libraries indexed with molecular tags

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Time-Resolved IR-Thermographic Detection and Screening of Enantioselectivity in Catalytic Reactions.

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Electrokinetic separation of chiral compounds

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Super-High-Throughput Screening of Enantioselective Catalysts by Using Capillary Array Electrophoresis

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Color Indicators of Molecular Chirality Based on Doped Liquid Crystals

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Super High Throughput Screening (SHTS) of Chiral Ligands and Activators: Asymmetric Activation of Chiral Diol-Zinc Catalysts by Chiral Nitrogen Activators for the Enantioselective Addition of Diethylzinc to Aldehydes

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Asymmetric activation of chiral alkoxyzinc catalysts by chiral nitrogen activators for dialkylzinc addition to aldehydes: super high-throughput screening of combinatorial libraries of chiral ligands and activators by HPLC-CD/UV and HPLC-OR/RIU syste

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Circular dichroism as a detection method in the screening of enantioselective catalysts

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Optical rotation per refractive index unit, or enantiomeric (e) factor, for screening enantioselective catalysts through asymmetric activation or carbohydrates

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A Method for High-Throughput Screening of Enantioselective Catalysts

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Measurement of Enantiomeric Excess by Kinetic Resolution and Mass Spectrometry

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7 January 2021

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Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12546918