RNAi: gene-silencing in therapeutic intervention (Q35053153)

6 August 2017

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title

RNAi: gene-silencing in therapeutic intervention (English)

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6 August 2017

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David J Shuey

1

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PubMed ID

12546893

6 August 2017

Daniel E McCallus

series ordinal

2

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PubMed ID

12546893

6 August 2017

Tony Giordano

series ordinal

3

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6 August 2017

1 October 2002

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6 August 2017

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6 August 2017

7

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6 August 2017

1040-1046

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6 August 2017

20

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Functional genomics and target validation approaches using antisense oligonucleotide technology

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNA as a drug target: methods for biophysical characterization and screening

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Gene targeting via triple-helix formation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNAi: nature abhors a double-strand

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNA interference is mediated by 21- and 22-nucleotide RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNA-dependent RNA polymerases, viruses, and RNA silencing

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Chalcone synthase cosuppression phenotypes in petunia flowers: comparison of sense vs. antisense constructs and single-copy vs. complex T-DNA sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Heritable gene silencing in Drosophila using double-stranded RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Double-stranded RNA injection produces null phenotypes in zebrafish.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Post-transcriptional suppression of gene expression in Xenopus embryos by small interfering RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNAi in mouse oocytes and preimplantation embryos: effectiveness of hairpin dsRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Identification of novel genes coding for small expressed RNAs

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

An extensive class of small RNAs in Caenorhabditis elegans

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https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Post-transcriptional gene silencing across kingdoms

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNA-triggered gene silencing

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Post-transcriptional gene silencing by double-stranded RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNA interference--2001.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

How cells respond to interferons

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNA viruses as inducers, suppressors and targets of post-transcriptional gene silencing

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNAi in C. elegans: soaking in the genome sequence

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

RNAi as random degradative PCR: siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Double-stranded RNA induces mRNA degradation in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Stable suppression of gene expression by RNAi in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Gene therapy: optimising DNA delivery to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

Characterization of a new class of DNA delivery complexes formed by the local anesthetic bupivacaine

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902474-1

7 January 2021

10.1016/S1359-6446(02)02474-1

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12546893