Efficient generation of gene-modified pigs via injection of zygote with Cas9/sgRNA. (Q35051026)

6 August 2017

Efficient generation of gene-modified pigs via injection of zygote with Cas9/sgRNA. (English)

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6 August 2017

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Yong Wang

1

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6 August 2017

Yinan Du

2

1 reference

6 August 2017

Bin Shen

3

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6 August 2017

Xiaoyang Zhou

4

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6 August 2017

Jian Li

5

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6 August 2017

Yu Liu

6

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6 August 2017

Jianying Wang

7

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6 August 2017

Jiankui Zhou

8

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6 August 2017

Bian Hu

9

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6 August 2017

Nannan Kang

10

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6 August 2017

Jimin Gao

11

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6 August 2017

Liqing Yu

12

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6 August 2017

Xingxu Huang

13

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6 August 2017

Hong Wei

14

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6 August 2017

language of work or name

English

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publication date

5 February 2015

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6 August 2017

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6 August 2017

5

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6 August 2017

8256

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Creative Commons Attribution 4.0 International

6 August 2017

start time

5 February 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/srep08256

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cites work

The meganuclease I-SceI containing nuclear localization signal (NLS-I-SceI) efficiently mediated mammalian germline transgenesis via embryo cytoplasmic microinjection

1 reference

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Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

A guide to genome engineering with programmable nucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

CRISPR-Cas systems for editing, regulating and targeting genomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Generation of GGTA1 biallelic knockout pigs via zinc-finger nucleases and somatic cell nuclear transfer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Highly efficient generation of GGTA1 biallelic knockout inbred mini-pigs with TALENs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Cas9 as a versatile tool for engineering biology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Efficient nonmeiotic allele introgression in livestock using custom endonucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

DNA targeting specificity of RNA-guided Cas9 nucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Precision editing of large animal genomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Efficient TALEN-mediated gene knockout in livestock

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

TAL effectors: customizable proteins for DNA targeting

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Xenobiotic metabolizing cytochrome P450 in pig, a promising animal model.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Genome editing with engineered zinc finger nucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Precision genetics for complex objectives in animal agriculture

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Bama miniature pigs (Sus scrofa domestica) as a model for drug evaluation for humans: comparison of in vitro metabolism and in vivo pharmacokinetics of lovastatin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

SeqMap: mapping massive amount of oligonucleotides to the genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

A future for transgenic livestock.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Altering the genome by homologous recombination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning

8 July 2018

1 reference

Influence of tissue origins and external microenvironment on porcine foetal fibroblast growth, proliferative life span and genome stability.

21 January 2018

1 reference

Phenotyping of transgenic cloned piglets.

21 January 2018

1 reference

Gene targeting in Drosophila and Caenorhabditis elegans with zinc-finger nucleases.

21 January 2018

1 reference

Generation of gene-modified mice via Cas9/RNA-mediated gene targeting

21 January 2018

1 reference

Generating rats with conditional alleles using CRISPR/Cas9.

21 January 2018

1 reference

Tissue distribution of CYP3A29 mRNA expression in Bama miniature pig by quantitative reverse transcriptase-polymerase chain reaction (RT-PCR).

21 January 2018

1 reference

Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

21 January 2018

1 reference

Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis

21 January 2018

1 reference

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.

21 January 2018

1 reference

Production of cloned pigs from in vitro systems.

21 January 2018

1 reference

Efficient generation of transgenic pigs using equine infectious anaemia virus (EIAV) derived vector.

21 January 2018

1 reference

Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4317696

Live pigs produced from genome edited zygotes

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25653176

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP08256

1 reference

6 August 2017

1 reference

6 August 2017

1 reference