Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene (Q35045775)

6 August 2017

title

Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene (English)

1 reference

6 August 2017

S Cory

4

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Andreas Strasser

object named as

A Strasser

series ordinal

1

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author name string

A W Harris

series ordinal

2

1 reference

6 August 2017

H von Boehmer

series ordinal

3

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6 August 2017

publication date

1 February 1994

1 reference

Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

language of work or name

English

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published in

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6 August 2017

volume

91

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6 August 2017

issue

4

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6 August 2017

page(s)

1376-1380

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A severe combined immunodeficiency mutation in the mouse

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Deletion of autospecific T cells in T cell receptor (TCR) transgenic mice spares cells with normal TCR levels and low levels of CD8 molecules

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Developmental biology of T cells in T cell-receptor transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4, and CD8 acquisition in vivo and in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Kinetics of mature T-cell development in the thymus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

The role of the T cell receptor in positive and negative selection of developing T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Peripheral selection of the T cell repertoire

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

An unusual lineage of alpha/beta T cells that contains autoreactive cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

In vivo administration of monoclonal antibodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

The level of CD8 expression can determine the outcome of thymic selection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

CD8 surface levels alter the fate of alpha/beta T cell receptor-expressing thymocytes in transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Exclusion and inclusion of α and β T cell receptor alleles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43161

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

9 December 2018

1 reference

12 December 2020

Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

1 reference

12 December 2020

Self-nonself discrimination by T cells

1 reference

12 December 2020

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1 reference

12 December 2020

In vivo calcium elevations in thymocytes with T cell receptors that are specific for self ligands

1 reference

12 December 2020

A self-reactive T cell population that is not subject to negative selection

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.91.4.1376

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6 August 2017

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6 August 2017

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