Identification of the IGF1/PI3K/NF κB/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer (Q35044404)

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English	Identification of the IGF1/PI3K/NF κB/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer	scientific article

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Identification of the IGF1/PI3K/NF κB/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer (English)

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Europe PubMed Central

6 August 2017

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Jeremy A. Squire

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Jeremy A Squire

13

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Madhuri Koti

1

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Europe PubMed Central

6 August 2017

Robert J Gooding

2

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Europe PubMed Central

6 August 2017

Paulo Nuin

3

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Europe PubMed Central

6 August 2017

Alexandria Haslehurst

4

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Europe PubMed Central

6 August 2017

Colleen Crane

5

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Europe PubMed Central

6 August 2017

Johanne Weberpals

6

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Europe PubMed Central

6 August 2017

Timothy Childs

7

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Europe PubMed Central

6 August 2017

Peter Bryson

8

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Europe PubMed Central

6 August 2017

Moyez Dharsee

9

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Europe PubMed Central

6 August 2017

Kenneth Evans

10

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Europe PubMed Central

6 August 2017

Harriet E Feilotter

11

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Europe PubMed Central

6 August 2017

Paul C Park

12

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Europe PubMed Central

6 August 2017

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16 November 2013

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Europe PubMed Central

6 August 2017

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Europe PubMed Central

6 August 2017

13

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Europe PubMed Central

6 August 2017

549

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Europe PubMed Central

6 August 2017

https://scigraph.springernature.com/pub.10.1186/1471-2407-13-549

0 references

Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling

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Assessing the range of kinase autoinhibition mechanisms in the insulin receptor family

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Effect of insulin analogues on insulin/IGF1 hybrid receptors: increased activation by glargine but not by its metabolites M1 and M2

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The changing view of high-grade serous ovarian cancer

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The insulin and insulin-like growth factor receptor family in neoplasia: an update

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Efficacy of anti-insulin-like growth factor I receptor monoclonal antibody cixutumumab in mesothelioma is highly correlated with insulin growth factor-I receptor sites/cell

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Epithelial-mesenchymal transition predicts sensitivity to the dual IGF-1R/IR inhibitor OSI-906 in hepatocellular carcinoma cell lines

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Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II.

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Rethinking ovarian cancer: recommendations for improving outcomes

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Serum IGF1, IGF2 and IGFBP3 and risk of advanced colorectal adenoma.

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Meta-analysis of gene expression profiles associated with histological classification and survival in 829 ovarian cancer samples.

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Targeted treatment of recurrent platinum-resistant ovarian cancer: current and emerging therapies

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The insulin-like growth factor 1 pathway is a potential therapeutic target for low-grade serous ovarian carcinoma

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FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

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An integrative approach to identifying cancer chemoresistance-associated pathways

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Compensatory insulin receptor (IR) activation on inhibition of insulin-like growth factor-1 receptor (IGF-1R): rationale for cotargeting IGF-1R and IR in cancer

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Pathway analysis of gene lists associated with platinum-based chemotherapy resistance in ovarian cancer: the big picture.

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Targeted therapies in epithelial ovarian cancer

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Identification of genes with differential expression in chemoresistant epithelial ovarian cancer using high-density oligonucleotide microarrays

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Treatment for recurrent ovarian cancer-at first relapse

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Potential predictive markers of chemotherapy resistance in stage III ovarian serous carcinomas

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Ovarian cancer pathogenesis: a model in evolution

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Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions

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beta-catenin small interfering RNA successfully suppressed progression of multiple myeloma in a mouse model

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Hyperactivation of the insulin-like growth factor receptor I signaling pathway is an essential event for cisplatin resistance of ovarian cancer cells

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Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas

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Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo.

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How to decide? Different methods of calculating gene expression from short oligonucleotide array data will give different results

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Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers

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High-resolution mapping of genomic imbalance and identification of gene expression profiles associated with differential chemotherapy response in serous epithelial ovarian cancer

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Serum insulin-like growth factor (IGF)-I, IGF binding protein (IGFBP)-3, leptin concentrations and insulin resistance in benign and malignant epithelial ovarian tumors in postmenopausal women

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12 December 2020

based on heuristic

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Serum insulin-like growth factors and mortality in localised and advanced clinically detected prostate cancer

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12 December 2020

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10.1186/1471-2407-13-549

1 reference

Europe PubMed Central

6 August 2017

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Europe PubMed Central

6 August 2017

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Europe PubMed Central

6 August 2017

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