Higher order chromatin degradation: implications for neurodegeneration (Q35039024)

5 August 2017

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title

Higher order chromatin degradation: implications for neurodegeneration (English)

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5 August 2017

Gregory W Konat

1

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5 August 2017

1 November 2002

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5 August 2017

Neurochemical Research

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5 August 2017

27

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5 August 2017

1447-1451

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5 August 2017

11

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https://scigraph.springernature.com/pub.10.1023/a:1021688119574

5 August 2017

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cites work

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Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinase

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DNA fragmentation into 200-250 and/or 30-50 kilobase pair fragments in rat liver nuclei is stimulated by Mg2+ alone and Ca2+/Mg2+ but not by Ca2+ alone.

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Periodicity of DNA folding in higher order chromatin structures

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Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes

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Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation

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Biological significance of unwinding capability of nuclear matrix-associating DNAs

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Involvement of Ca2+ in the formation of high molecular weight DNA fragments in thymocyte apoptosis.

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A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition

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Investigation of the mechanism of higher order chromatin fragmentation observed in drug-induced apoptosis.

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The histone HS gene is flanked by S1 hypersensitive structures

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Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes

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Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease

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Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis

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Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes.

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Mechanisms of induction of apoptotic DNA fragmentation.

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Chromatin condensation is not associated with apoptosis

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Separate pools of endonuclease activity are responsible for internucleosomal and high molecular mass DNA fragmentation during apoptosis.

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The role of free radicals in toxicity and disease

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Endonuclease activities associated with high molecular weight and internucleosomal DNA fragmentation in apoptosis.

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Degradation of lamin B1 precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei.

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DNA conformation at the 5′ end of the chicken adult β-globin gene

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Compartmentalization of interphase chromosomes observed in simulation and experiment

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Torsional stress induces an S1 nuclease-hypersensitive site within the promoter of the Xenopus laevis oocyte-type 5S RNA gene

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A novel signature mutation for oxidative damage resembles a mutational pattern found commonly in human cancers

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Review: chromatin structural features and targets that regulate transcription

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Role of intracellular calcium in hydrogen peroxide-induced renal tubular cell injury

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Higher order structure of chromosomes

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12 December 2020

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Mg(2+)-dependent cleavage of DNA into kilobase pair fragments is responsible for the initial degradation of DNA in apoptosis

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12 December 2020

Large-scale fragmentation of mammalian DNA in the course of apoptosis proceeds via excision of chromosomal DNA loops and their oligomers

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DNA structure equilibria in the human c-myc gene

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Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

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Hydrogen peroxide induces rapid digestion of oligodendrocyte chromatin into high molecular weight fragments

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12 December 2020

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Fas mediates apoptosis in human monocytes by a reactive oxygen intermediate dependent pathway

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12 December 2020

Identifiers

DOI

10.1023/A:1021688119574

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PubMed ID

12512948

Dimensions Publication ID

5 August 2017

0 references

1 reference

PubMed ID

12512948