Activation of Notch signaling is required for cholangiocarcinoma progression and is enhanced by inactivation of p53 in vivo (Q35035238)

5 August 2017

Activation of Notch signaling is required for cholangiocarcinoma progression and is enhanced by inactivation of p53 in vivo (English)

1 reference

5 August 2017

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Mona El Khatib

1

1 reference

5 August 2017

Przemyslaw Bozko

2

1 reference

5 August 2017

Vindhya Palagani

3

1 reference

5 August 2017

Nisar P Malek

4

1 reference

5 August 2017

Ludwig Wilkens

5

1 reference

5 August 2017

Ruben R Plentz

6

1 reference

5 August 2017

language of work or name

English

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publication date

30 October 2013

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5 August 2017

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5 August 2017

8

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5 August 2017

10

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5 August 2017

e77433

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Creative Commons Attribution 4.0 International

5 August 2017

start time

30 October 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

The roles of Notch1 expression in the migration of intrahepatic cholangiocarcinoma

1 reference

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Guidelines for the diagnosis and treatment of cholangiocarcinoma: an update

8 July 2018

1 reference

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Cholangiocarcinomas can originate from hepatocytes in mice

8 July 2018

1 reference

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E/N-cadherin switch mediates cancer progression via TGF-β-induced epithelial-to-mesenchymal transition in extrahepatic cholangiocarcinoma

8 July 2018

1 reference

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Clinicopathological significance of altered Notch signaling in extrahepatic cholangiocarcinoma and gallbladder carcinoma

8 July 2018

1 reference

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Epithelial-Mesenchymal Transition in tumor microenvironment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Risk factors for cholangiocarcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Mutational profiling reveals PIK3CA mutations in gallbladder carcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

New insights on cholangiocarcinoma.

8 July 2018

1 reference

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Notch signaling in solid tumors.

8 July 2018

1 reference

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Genetics of biliary tract cancers and emerging targeted therapies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Impact of classification of hilar cholangiocarcinomas (Klatskin tumors) on the incidence of intra- and extrahepatic cholangiocarcinoma in the United States

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Combination chemotherapy with gemcitabine and cisplatin as first-line treatment for immunohistochemically proven cholangiocarcinoma

8 July 2018

1 reference

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Complex networks orchestrate epithelial-mesenchymal transitions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

8 July 2018

1 reference

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p53 Mutations in human cholangiocarcinoma: a review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Cadherin switching: essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

The epidemiology of cholangiocarcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Notch signaling controls multiple steps of pancreatic differentiation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Notch signaling: cell fate control and signal integration in development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Liver, gallbladder, extrahepatic bile ducts, and pancreas

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3813685

Epidemiological trends in incidence and mortality of hepatobiliary cancers in Germany.

8 July 2018

1 reference

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Photodynamic therapy for non-resectable perihilar cholangiocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0077433

Frequency of p16(INK4A) alterations and K-ras mutations in intrahepatic cholangiocarcinoma of the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0077433

Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0077433

Phase II study of gemcitabine and cisplatin as first-line chemotherapy in inoperable biliary tract carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0077433

Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0077433

Inhibition of Jagged-mediated Notch signaling disrupts zebrafish biliary development and generates multi-organ defects compatible with an Alagille syndrome phenocopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0077433

Notch signaling controls liver development by regulating biliary differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0077433

Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0077433

Constitutive Notch2 signaling induces hepatic tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0077433

A critical role for notch signaling in the formation of cholangiocellular carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0077433

Hepatocyte-specific expression of Cre recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0077433

Eastern cooperative oncology group experience with chemotherapy for inoperable gallbladder and bile duct cancer

21 January 2018

1 reference

12 December 2020

Mutations of p53 tumor suppressor gene, apoptosis, and proliferation in intrahepatic cholangiocellular carcinoma of the liver

1 reference

12 December 2020

Protein expression and genetic alterations of p53 and ras in intrahepatic cholangiocarcinoma

1 reference

12 December 2020

High lifetime risk of cancer in primary sclerosing cholangitis

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0077433

Identifiers

DOI

1 reference

release_teidcp7bhvanvlqnfdh7nvn4ei

5 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/teidcp7bhvanvlqnfdh7nvn4ei

24 November 2022

mapped directly with Wikidata item

PMCID

3813685

1 reference

5 August 2017

1 reference