Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome (Q35025096)

5 August 2017

Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome (English)

1 reference

5 August 2017

Marina V Rodnina

3

0 references

Andreas Savelsbergh

series ordinal

2

object named as

Andreas Savelsbergh

1 reference

5 August 2017

4

Wolfgang Wintermeyer

1 reference

5 August 2017

Berthold Wilden

1

1 reference

PubMed ID

16940356

5 August 2017

language of work or name

English

0 references

publication date

29 August 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

1 reference

5 August 2017

103

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5 August 2017

37

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5 August 2017

13670-13675

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The hybrid state of tRNA binding is an authentic translation elongation intermediate

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Control of phosphate release from elongation factor G by ribosomal protein L7/12.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Guanine-nucleotide exchange on ribosome-bound elongation factor G initiates the translocation of tRNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Locking and unlocking of ribosomal motions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

A ratchet-like inter-subunit reorganization of the ribosome during translocation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Arginines 29 and 59 of elongation factor G are important for GTP hydrolysis or translocation on the ribosome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Large-scale movement of elongation factor G and extensive conformational change of the ribosome during translocation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Thiostrepton inhibits the turnover but not the GTPase of elongation factor G on the ribosome.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Complete kinetic mechanism of elongation factor Tu-dependent binding of aminoacyl-tRNA to the A site of the E. coli ribosome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Visualization of elongation factor G on the Escherichia coli 70S ribosome: the mechanism of translocation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

The structure of elongation factor G in complex with GDP: conformational flexibility and nucleotide exchange

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

GTP consumption of elongation factor Tu during translation of heteropolymeric mRNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Ribosomal translocation: facts and models

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

Studies on Polypeptide-Chain-Elongation Factors from an Extreme Thermophile, Thermus thermophilus HB8. 2. Catalytic Properties

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

The role of guanosine 5′-triphosphate in polypeptide chain elongation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1564220

EF-G-dependent GTPase on the ribosome. conformational change and fusidic acid inhibition.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606099103

An elongation factor G-induced ribosome rearrangement precedes tRNA-mRNA translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606099103

Coupling of GTP hydrolysis by elongation factor G to translocation and factor recycling on the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606099103

Conformational changes of the small ribosomal subunit during elongation factor G-dependent tRNA-mRNA translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606099103

Kinetics and thermodynamics of RRF, EF-G, and thiostrepton interaction on the Escherichia coli ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606099103

Rapid kinetic analysis of EF-G-dependent mRNA translocation in the ribosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606099103

Crystal structure of a mutant elongation factor G trapped with a GTP analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606099103

Structural insights into fusidic acid resistance and sensitivity in EF-G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606099103

Transient conformational states of aminoacyl-tRNA during ribosome binding catalyzed by elongation factor Tu.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606099103

Equilibrium measurements of the interactions of guanine nucleotides with Escherichia coli elongation factor G and the ribosome

21 January 2018

1 reference

12 December 2020

The conformational properties of elongation factor G and the mechanism of translocation

1 reference

12 December 2020

Conformationally Restricted Elongation Factor G Retains GTPase Activity but Is Inactive in Translocation on the Ribosome

1 reference

12 December 2020

Further studies on the interaction of the polypeptide chain elongation factor G with guanine nucleotides

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0606099103

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference

PubMed ID

16940356