Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma (Q35022888)

5 August 2017

Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma (English)

1 reference

5 August 2017

1 reference

Song Han

1

1 reference

5 August 2017

Constance W Lee

2

1 reference

5 August 2017

Jose G Trevino

3

1 reference

5 August 2017

Steven J Hughes

4

1 reference

5 August 2017

George A Sarosi

5

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5 August 2017

language of work or name

English

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publication date

11 October 2013

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5 August 2017

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5 August 2017

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5 August 2017

10

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5 August 2017

e76667

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Creative Commons CC0 License

5 August 2017

start time

11 October 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3795734/fullTextXML

inferred from PubMed Central ID database lookup

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Phase II study of gemcitabine in combination with regional arterial infusion of nafamostat mesilate for advanced pancreatic cancer.

8 July 2018

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PRSS3 promotes tumour growth and metastasis of human pancreatic cancer

8 July 2018

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Proteinase-activated receptor-2 in the pathogenesis of gastroesophageal reflux disease

8 July 2018

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Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109

8 July 2018

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Combination chemotherapy of nafamostat mesilate with gemcitabine for pancreatic cancer targeting NF-kappaB activation.

8 July 2018

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Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration

8 July 2018

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8 July 2018

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Protease-activated receptor 2, dipeptidyl peptidase I, and proteases mediate Clostridium difficile toxin A enteritis.

8 July 2018

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Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death

8 July 2018

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Bile salt exposure increases proliferation through p38 and ERK MAPK pathways in a non-neoplastic Barrett's cell line

8 July 2018

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Roles of platelets and proteinase-activated receptors in gastric ulcer healing.

8 July 2018

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Proinflammatory role of trypsin and protease-activated receptor-2 in a rat model of acute pancreatitis

8 July 2018

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Physiology and pathophysiology of proteinase-activated receptors (PARs): PAR-2-mediated proliferation of colon cancer cell.

8 July 2018

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Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation

8 July 2018

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Human Mesotrypsin Is a Unique Digestive Protease Specialized for the Degradation of Trypsin Inhibitors

8 July 2018

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Trypsin is produced by and activates protease-activated receptor-2 in human cancer colon cells: evidence for new autocrine loop

8 July 2018

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Enhanced invasiveness of pancreatic adenocarcinoma cells stably transfected with cationic trypsinogen cDNA.

8 July 2018

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Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2

8 July 2018

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8 July 2018

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Thrombin signalling and protease-activated receptors

8 July 2018

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Stimulation of cellular growth and adhesion to fibronectin and vitronectin in culture and tumorigenicity in nude mice by overexpression of trypsinogen in human gastric cancer cells

8 July 2018

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Molecular cloning of a potential proteinase activated receptor

8 July 2018

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Characterization of human exocrine pancreatic proteins by two-dimensional isoelectric focusing/sodium dodecyl sulfate gel electrophoresis.

8 July 2018

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Expression of protease-activated-receptor 2 (PAR-2) in human esophageal mucosa.

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0076667

Tumor-derived trypsin enhances proliferation of intrahepatic cholangiocarcinoma cells by activating protease-activated receptor-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0076667

Trypsin IV, a novel agonist of protease-activated receptors 2 and 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0076667

Protection against acute pancreatitis by activation of protease-activated receptor-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0076667

A phase I study of full-dose gemcitabine and regional arterial infusion of nafamostat mesilate for advanced pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0076667

A role for protease-activated receptor-2 in pancreatic cancer cell proliferation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795734

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795734

Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24146905

12 December 2020

inferred from PubMed ID database lookup

Trypsin stimulates integrin alpha(5)beta(1)-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24146905

12 December 2020

inferred from PubMed ID database lookup

Expression of pancreatic trypsinogen/trypsin and cathepsin B in human cholangiocarcinomas and hepatocellular carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24146905

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0076667

1 reference

5 August 2017

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1 reference

5 August 2017

1 reference