Role of the active site guanine in the glmS ribozyme self-cleavage mechanism: quantum mechanical/molecular mechanical free energy simulations (Q35020704)

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English	Role of the active site guanine in the glmS ribozyme self-cleavage mechanism: quantum mechanical/molecular mechanical free energy simulations	scientific article

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scholarly article

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Europe PubMed Central

5 August 2017

Role of the active site guanine in the glmS ribozyme self-cleavage mechanism: quantum mechanical/molecular mechanical free energy simulations (English)

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Europe PubMed Central

5 August 2017

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Sharon Hammes-Schiffer

6

object named as

Sharon Hammes-Schiffer

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Europe PubMed Central

5 August 2017

Jamie L Bingaman

4

object named as

Jamie L Bingaman

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Europe PubMed Central

5 August 2017

author name string

Sixue Zhang

1

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Europe PubMed Central

5 August 2017

Abir Ganguly

2

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Europe PubMed Central

5 August 2017

Puja Goyal

3

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Europe PubMed Central

5 August 2017

Philip C Bevilacqua

5

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Europe PubMed Central

5 August 2017

language of work or name

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publication date

12 January 2015

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Europe PubMed Central

5 August 2017

Journal of the American Chemical Society

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Europe PubMed Central

5 August 2017

137

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Europe PubMed Central

5 August 2017

2

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Europe PubMed Central

5 August 2017

784-798

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Europe PubMed Central

5 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4308743/fullTextXML

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Crystal structure and mechanistic investigation of the twister ribozyme

1 reference

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1 reference

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1 reference

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Quantum mechanical/molecular mechanical free energy simulations of the self-cleavage reaction in the hepatitis delta virus ribozyme

1 reference

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A widespread self-cleaving ribozyme class is revealed by bioinformatics.

1 reference

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1 reference

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1 reference

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1 reference

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General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.

1 reference

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QM/MM studies of hairpin ribozyme self-cleavage suggest the feasibility of multiple competing reaction mechanisms

1 reference

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An active-site guanine participates in glmS ribozyme catalysis in its protonated state

1 reference

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The glmS ribozyme tunes the catalytically critical pK(a) of its coenzyme glucosamine-6-phosphate

1 reference

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1 reference

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Rapid steps in the glmS ribozyme catalytic pathway: cation and ligand requirements

1 reference

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1 reference

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Analysis of metal ion dependence in glmS ribozyme self-cleavage and coenzyme binding

1 reference

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1 reference

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1 reference

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Essential role of an active-site guanine in glmS ribozyme catalysis

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Requirement of Helix P2.2 and Nucleotide G1 for Positioning the Cleavage Site and Cofactor of the glmS Ribozyme

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1 reference

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1 reference

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1 reference

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Identifiers

10.1021/JA510387Y

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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