Of mice and models: improved animal models for biomedical research (Q35016224)

5 August 2017

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title

Of mice and models: improved animal models for biomedical research (English)

1 reference

5 August 2017

Ernesto Bockamp

1

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5 August 2017

Marko Maringer

2

1 reference

5 August 2017

Christian Spangenberg

3

1 reference

5 August 2017

Stephan Fees

4

1 reference

5 August 2017

Stuart Fraser

5

1 reference

5 August 2017

Leonid Eshkind

6

1 reference

5 August 2017

Franz Oesch

7

1 reference

5 August 2017

Bernhard Zabel

8

1 reference

5 August 2017

3 December 2002

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5 August 2017

Physiological Genomics

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5 August 2017

11

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5 August 2017

3

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5 August 2017

115-132

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A novel tetracycline-dependent transactivator with E2F4 transcriptional activation domain

5 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Co-regulation of two gene activities by tetracycline via a bidirectional promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

A transgenic model of transactivation by the Tax protein of HTLV-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Targeting of an inducible toxic phenotype in animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Decreased ethanol sensitivity and tolerance development in gamma-protein kinase C null mutant mice is dependent on genetic background.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Spatio-temporally controlled site-specific somatic mutagenesis in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Single-copy transgenic mice with chosen-site integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Improved properties of FLP recombinase evolved by cycling mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Alteration of Cre recombinase site specificity by substrate-linked protein evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Genetic ablation of parietal cells in transgenic mice: a new model for analyzing cell lineage relationships in the gastric mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Steroid receptor family: structure and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

A new positive/negative selectable marker, puDeltatk, for use in embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Essential role for oncogenic Ras in tumour maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

The lac operator-repressor system is functional in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Efficient generation of transgenic BALB/c mice using BALB/c embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Variegated gene expression in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Thy-1 tk transgenic mice with a conditional lymphocyte deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Antisense transgenics in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Gene trapping and functional genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Establishment in culture of pluripotential cells from mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

The steroid and thyroid hormone receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Targeting the Hprt locus in mice reveals differential regulation of Tie2 gene expression in the endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Locus control regions and epigenetic chromatin modifiers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Tetracycline-inducible expression systems with reduced basal activity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

A tetracycline controlled activation/repression system with increased potential for gene transfer into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Spatial and temporal regulation of a lacZ reporter transgene in a binary transgenic mouse system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Genetic transformation of mouse embryos by microinjection of purified DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Transcriptional activation by tetracyclines in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Mouse models for human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Long-term, noninvasive imaging of regulated gene expression in living mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

P1 site-specific recombination: nucleotide sequence of the recombining sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Adenovirus-mediated inducible gene expression in vivo by a hybrid ecdysone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Reversibility of acute B-cell leukaemia induced by BCR-ABL1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

The protooncogene c-jun contains an unusual estrogen-inducible enhancer within the coding sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

21 January 2018

Modeling cancer in mice

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Genetic regulatory mechanisms in the synthesis of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Conditional mouse models of sporadic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Identification of gene function and functional pathways by systemic plasmid-based ribozyme targeting in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Inducible site-specific recombination in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Tetracycline-controlled expression but not toxicity of an attenuated diphtheria toxin mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Gene transactivation mediated by the TAT gene of human immunodeficiency virus in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Site-specific recombinases: tools for genome engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Locus control regions: overcoming heterochromatin-induced gene inactivation in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Targeted disruption of the MHC class II Aa gene in C57BL/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

A GFP-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Inducible gene targeting in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Conditional alleles in mice: practical considerations for tissue-specific knockouts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Targeted oncogene activation by site-specific recombination in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Reduced beta 2-microglobulin mRNA levels in transgenic mice expressing a designed hammerhead ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Conditional Gene Knockout Using Cre Recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Establishment of a germ-line competent C57BL/6 embryonic stem cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Conditional lineage ablation to model human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Conditional control of gene expression in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Timing the doxycycline yields different patterns of genomic recombination in brain neurons with a new inducible Cre transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Synthetic hammerhead ribozymes as tools in gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Tetracycline-regulated gene expression in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Site- and time-specific gene targeting in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Inducible gene targeting in postnatal myocardium by cardiac-specific expression of a hormone-activated Cre fusion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Cre recombinase: The universal reagent for genome tailoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Concise review of the cytochrome P450s and their roles in toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Tissue- and site-specific DNA recombination in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

beta-YAC transgenic mice for studying LCR function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Complications associated with genetic background effects in research using knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Regulation of protein function through expression of chimaeric proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Regulable Expression of Inhibin A in Wild-Type and Inhibin Null Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Steroid receptor interactions with heat shock protein and immunophilin chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Insertional mutagenesis in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Seven-transmembrane-spanning receptors and heart function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Chimeras and mosaics in mouse mutant analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Conditional transgenic technologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Inducible gene knockouts in the small intestinal and colonic epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Identification of ligands and coligands for the ecdysone-regulated gene switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Influence of genetic background on knockout mouse phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Directed evolution of the site specificity of Cre recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Efficient control of gene expression by single step integration of the tetracycline system in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Temporally and spatially regulated somatic mutagenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Targeted ablation of gonadotrophs in transgenic mice affects embryonic development of lactotrophs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Codon-improved Cre recombinase (iCre) expression in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

The temporal requirement for endothelin receptor-B signalling during neural crest development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Viewpoint: are studies in genetically altered mice out of control?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Distinct 5' SCL enhancers direct transcription to developing brain, spinal cord, and endothelium: neural expression is mediated by GATA factor binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Capturing genes encoding membrane and secreted proteins important for mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Nature's universal oxygenases: the cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Insertion of DNA sequences into the human chromosomal beta-globin locus by homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

The p65 domain from NF-kappaB is an efficient human activator in the tetracycline-regulatable gene expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Codon optimization markedly improves doxycycline regulated gene expression in the mouse heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Cancer modeling in the modern era: progress and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Conditional ablation of the osteoblast lineage in Col2.3deltatk transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Cloning of male mice from adult tail-tip cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

A regulatory system for use in gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Transgenic animals in integrative biology: approaches and interpretations of outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Position effects on eukaryotic gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Genetic mosaic analysis based on Cre recombinase and navigated laser capture microdissection

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

New variants of inducible Cre recombinase: a novel mutant of Cre-PR fusion protein exhibits enhanced sensitivity and an expanded range of inducibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

The ons and offs of inducible transgenic technology: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Functional ecdysone receptor is the product of EcR and Ultraspiracle genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Engineering chromosomal rearrangements in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Identification of selective estrogen receptor modulators by their gene expression fingerprints

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Use of the tetracycline-controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

Targetted correction of a mutant HPRT gene in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOLGENOMICS.00067.2002

10.1152/PHYSIOLGENOMICS.00067.2002

21 January 2018

Identifiers

DOI

1 reference

5 August 2017

1 reference